| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Enchanted | $401,159 | -20.9% | 89 | +5 | $4,507 | $1,214,721 | 2 | Walt Disney Pictures | false | false |
| 2 | 2 | I Am Legend | $319,827 | -32% | 75 | +1 | $4,264 | $1,148,057 | 3 | Warner Bros. | false | false |
| 3 | - | Aliens vs. Predator: Requiem | $162,775 | - | 41 | - | $3,970 | $162,775 | 1 | 20th Century Fox International | true | false |
| 4 | 3 | American Gangster | $131,217 | -25.9% | 51 | -2 | $2,572 | $384,074 | 2 | United International Pictures | false | false |
| 5 | 5 | Alvin and the Chipmunks | $98,604 | -13.6% | 63 | -6 | $1,565 | $291,458 | 2 | 20th Century Fox International | false | false |
| 6 | 4 | The Golden Compass | $92,004 | -21.5% | 84 | +7 | $1,095 | $1,185,910 | 5 | Distribution Company | false | false |
| 7 | 6 | I Could Never Be Your Woman | $57,576 | -21.4% | 34 | +2 | $1,693 | $167,506 | 2 | CDI Films | false | false |
| 8 | - | Sleuth | $47,377 | - | 11 | - | $4,307 | $47,377 | 1 | Sony Pictures Releasing | true | false |
| 9 | - | Bridge to Terabithia | $42,437 | - | 36 | - | $1,178 | $42,437 | 1 | United International Pictures | true | false |
| 10 | - | August Rush | $37,368 | - | 42 | - | $889 | $37,368 | 1 | Distribution Company | true | false |
| 11 | 9 | The Heartbreak Kid | $35,639 | +41% | 33 | +11 | $1,079 | $745,541 | 10 | United International Pictures | false | false |
| 12 | 7 | Bee Movie | $31,931 | -46.7% | 77 | -23 | $414 | $1,408,317 | 6 | United International Pictures | false | false |
| 13 | 8 | My Best Friend | $20,787 | -43% | 15 | -1 | $1,385 | $70,082 | 2 | Alfa Films | false | false |
| 14 | 12 | Gone Baby Gone | $12,790 | +30.8% | 18 | +6 | $710 | $331,050 | 8 | Walt Disney Pictures | false | false |
| 15 | 10 | Beowulf | $10,032 | -40.7% | 39 | -3 | $257 | $688,382 | 8 | Warner Bros. | false | false |
| 16 | 21 | The Flock | $9,463 | +201.2% | 23 | +12 | $411 | $173,977 | 6 | CDI Films | false | false |
| 17 | 14 | 4 Months, 3 Weeks and 2 Days | $6,051 | -25.7% | 11 | +3 | $550 | $168,708 | 6 | Pachamama Cine | false | false |
| 18 | 13 | Lions for Lambs | $4,373 | -46.8% | 25 | -7 | $174 | $497,470 | 9 | 20th Century Fox International | false | false |
| 19 | 16 | Days of Glory | $4,183 | -42.9% | 5 | - | $836 | $14,082 | 2 | Alfa Films | false | false |
| 20 | 15 | The Assassination of Jesse James by the Coward Robert Ford | $3,440 | -53.3% | 9 | -5 | $382 | $142,573 | 7 | Warner Bros. | false | false |
| 21 | 20 | Café Lumière 2007 Re-release | $3,297 | +0.3% | 2 | - | $1,648 | $36,790 | 5 | 791 Cine | false | false |
| 22 | 23 | After the Wedding | $3,294 | +32.7% | 7 | +2 | $470 | $100,638 | 8 | Alfa Films | false | false |
| 23 | - | Suspiros del corazón | $2,764 | - | 4 | - | $691 | $2,764 | 1 | Primer Plano Film Group | true | false |
| 24 | 18 | The Hitcher | $2,760 | -37.8% | 9 | +1 | $306 | $129,779 | 6 | Distribution Company | false | false |
| 25 | - | The Black Dahlia | $2,633 | - | 2 | - | $1,316 | $59,922 | 8 | United International Pictures | false | false |
| 26 | 26 | Lonely Hearts | $2,479 | +171.2% | 7 | +4 | $354 | $98,830 | 7 | Distribution Company | false | false |
| 27 | 19 | Saw IV | $2,271 | -38.9% | 15 | -9 | $151 | $1,006,489 | 11 | Walt Disney Pictures | false | false |
| 28 | 11 | Superbad | $2,271 | -82% | 14 | -13 | $162 | $391,648 | 8 | Sony Pictures Releasing | false | false |
| 29 | 17 | Retribution | $1,345 | -79.5% | 5 | -7 | $269 | $108,933 | 5 | Pachamama Cine | false | false |
| 30 | 22 | Shattered | $613 | -75.6% | 6 | -11 | $102 | $324,958 | 10 | Distribution Company | false | false |
| 31 | 34 | Whisper | $551 | +102.6% | 2 | -3 | $275 | $110,393 | 7 | Alfa Films | false | false |
| 32 | - | Hechos, No Palabras | $505 | - | 1 | - | $505 | $505 | 1 | Primer Plano Film Group | true | false |
| 33 | 30 | Next | $502 | +8.7% | 1 | -2 | $502 | $319,515 | 16 | United International Pictures | false | false |
| 34 | 24 | Underdog | $441 | -71.4% | 12 | -12 | $36 | $849,602 | 15 | Walt Disney Pictures | false | false |
| 35 | 28 | Resident Evil: Extinction | $419 | -21.4% | 3 | -3 | $139 | $550,303 | 14 | Sony Pictures Releasing | false | false |
| 36 | 25 | The Last Kiss | $410 | -72.1% | 1 | -2 | $410 | $48,271 | 6 | United International Pictures | false | false |
| 37 | 27 | The Painted Veil | $407 | -26.1% | 3 | - | $135 | $364,422 | 15 | Distribution Company | false | false |
| 38 | 33 | Rendition | $379 | +32.1% | 3 | - | $126 | $421,777 | 11 | Distribution Company | false | false |
| 39 | 39 | Halloween | $320 | +89.3% | 4 | +2 | $80 | $206,325 | 10 | Alfa Films | false | false |
| 40 | 32 | Estrellas | $312 | -15.7% | 1 | - | $312 | $13,741 | 5 | Primer Plano Film Group | false | false |
| 41 | 37 | Sicko | $279 | +30.4% | 1 | - | $279 | $66,941 | 17 | Alfa Films | false | false |
| 42 | 40 | Encarnacion | $250 | +50.6% | 1 | - | $250 | $39,892 | 14 | Distribution Company | false | false |
| 43 | 42 | Quiéreme | $246 | +59.7% | 3 | -2 | $82 | $62,230 | 9 | Alfa Films | false | false |
| 44 | 38 | Shortbus | $234 | +10.9% | 1 | - | $234 | $28,542 | 11 | Distribution Company | false | false |
| 45 | 43 | El resultado del amor | $219 | +56.4% | 1 | - | $219 | $61,927 | 22 | Primer Plano Film Group | false | false |
| 46 | 31 | The 11th Hour | $210 | -53.9% | 1 | -1 | $210 | $14,124 | 6 | Warner Bros. | false | false |
| 47 | - | Knocked Up | $170 | - | 1 | - | $170 | $186,229 | 13 | United International Pictures | false | false |
| 48 | - | Black Book | $99 | - | 1 | - | $99 | $468,623 | 21 | Pachamama Cine | false | false |
| 49 | 29 | Vitus | $70 | -86.1% | 1 | -1 | $70 | $48,169 | 9 | CDI Films | false | false |
| 50 | - | The Invasion | $67 | - | 1 | - | $67 | $321,586 | 15 | Warner Bros. | false | false |
| 51 | 44 | The Seeker: The Dark Is Rising | $61 | -47.9% | 2 | -6 | $30 | $150,262 | 11 | 20th Century Fox International | false | false |
| 52 | - | Música nocturna | $45 | - | 1 | - | $45 | $25,572 | 9 | Primer Plano Film Group | false | false |
| 53 | 49 | Fierro | $42 | +82.6% | 1 | - | $42 | $153,987 | 10 | Primer Plano Film Group | false | false |
| 54 | 41 | Lights in the Dusk | $40 | -74.8% | 1 | - | $40 | $50,752 | 16 | Alfa Films | false | false |
| 55 | 48 | Michael Clayton | $39 | -18.8% | 3 | -6 | $13 | $558,899 | 14 | Alfa Films | false | false |
| 56 | - | The Simpsons Movie | $29 | - | 3 | - | $9 | $7,310,433 | 25 | 20th Century Fox International | false | false |
