| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Cloverfield | $2,232,948 | - | 235 | - | $9,501 | $2,232,948 | 1 | Paramount Pictures International | true | false |
| 2 | 2 | 27 Dresses | $2,217,953 | -29.5% | 249 | +9 | $8,907 | $7,014,908 | 2 | 20th Century Fox International | false | false |
| 3 | 4 | Alvin and the Chipmunks | $1,695,533 | -28.5% | 253 | -9 | $6,701 | $11,380,700 | 3 | 20th Century Fox International | false | false |
| 4 | 3 | American Gangster | $1,694,901 | -42.6% | 255 | - | $6,646 | $5,744,580 | 2 | Universal Pictures International (UPI) | false | false |
| 5 | - | Juno | $1,632,160 | - | 168 | - | $9,715 | $1,669,173 | 1 | 20th Century Fox International | true | false |
| 6 | 1 | I Am Legend | $1,600,144 | -49.8% | 288 | -50 | $5,556 | $17,189,074 | 3 | Roadshow Films | false | false |
| 7 | 5 | The Water Horse | $939,297 | -9% | 195 | +5 | $4,816 | $2,725,361 | 2 | Sony Pictures Releasing | false | false |
| 8 | 6 | The Golden Compass | $652,404 | -33.2% | 277 | -13 | $2,355 | $11,708,177 | 4 | Roadshow Films | false | false |
| 9 | 7 | Enchanted | $609,003 | -28.5% | 275 | -5 | $2,214 | $9,634,091 | 4 | Walt Disney Pictures | false | false |
| 10 | 8 | Atonement | $565,592 | -21.9% | 150 | -6 | $3,770 | $7,011,112 | 4 | Universal Pictures International (UPI) | false | false |
| 11 | - | The Kite Runner | $340,241 | - | 44 | - | $7,732 | $340,241 | 1 | Paramount Pictures International | true | false |
| 12 | 9 | National Treasure: Book of Secrets | $337,112 | -44% | 188 | -72 | $1,793 | $10,946,241 | 5 | Walt Disney Pictures | false | false |
| 13 | 10 | P.S. I Love You | $278,859 | -38.1% | 140 | -29 | $1,991 | $4,428,060 | 4 | Hoyts Distribution | false | false |
| 14 | 11 | No Country for Old Men | $226,297 | -31.9% | 52 | -2 | $4,351 | $2,755,025 | 4 | Paramount Pictures International | false | false |
| 15 | 12 | Bee Movie | $187,261 | -35.2% | 153 | -50 | $1,223 | $12,789,102 | 7 | Paramount Pictures International | false | false |
| 16 | - | Lust, Caution | $120,004 | - | 11 | - | $10,909 | $159,529 | 1 | Park Circus | true | false |
| 17 | 15 | Two Days in Paris | $118,822 | -23.9% | 11 | -11 | $10,802 | $1,064,151 | 4 | Hopscotch Films | false | false |
| 18 | 16 | Death at a Funeral | $109,879 | -28.1% | 82 | -14 | $1,339 | $13,445,317 | 15 | Icon Film Distribution | false | false |
| 19 | 14 | The Darjeeling Limited | $91,900 | -47.2% | 49 | -5 | $1,875 | $1,595,044 | 4 | 20th Century Fox International | false | false |
| 20 | 13 | Aliens vs. Predator: Requiem | $70,187 | -71.8% | 59 | -105 | $1,189 | $4,893,264 | 4 | 20th Century Fox International | false | false |
| 21 | 17 | Mr. Magorium's Wonder Emporium | $47,983 | -47.3% | 64 | -30 | $749 | $4,850,312 | 6 | Roadshow Films | false | false |
| 22 | 21 | I'm Not There | $46,149 | -19.9% | 23 | +3 | $2,006 | $513,182 | 4 | Icon Film Distribution | false | false |
| 23 | 20 | Beowulf | $41,575 | -30.2% | 21 | -6 | $1,979 | $6,510,332 | 8 | Warner Bros. | false | false |
| 24 | 19 | Into the Wild | $37,163 | -38.7% | 21 | -4 | $1,769 | $1,686,175 | 8 | Paramount Pictures International | false | false |
| 25 | 23 | As It Is in Heaven | $16,995 | +8% | 8 | +1 | $2,124 | $2,779,317 | 77 | Rialto Distribution | false | false |
| 26 | 26 | Conversations with My Gardener | $10,622 | +26.8% | 5 | - | $2,124 | $387,759 | 11 | Rialto Distribution | false | false |
| 27 | - | Grindhouse | $10,615 | - | 1 | - | $10,615 | $20,315 | 6 | Roadshow Films | false | false |
| 28 | 22 | I Served the King of England | $7,452 | -58.5% | 7 | - | $1,064 | $162,538 | 4 | Rialto Distribution | false | false |
| 29 | 29 | Hitman | $6,859 | +63.2% | 6 | - | $1,143 | $3,702,773 | 7 | 20th Century Fox International | false | false |
| 30 | - | Bombay to Bangkok | $5,608 | - | 6 | - | $934 | $5,608 | 1 | Eros Worldwide | true | false |
| 31 | 25 | Elizabeth: The Golden Age | $4,864 | -50% | 9 | -5 | $540 | $4,357,969 | 10 | Universal Pictures International (UPI) | false | false |
| 32 | - | Transylvania | $2,942 | - | 1 | - | $2,942 | $6,809 | 1 | Potential Films | true | false |
| 33 | 27 | The Last Mistress | $2,728 | -40.6% | 2 | - | $1,364 | $91,677 | 10 | Potential Films | false | false |
| 34 | 28 | Private Fears in Public Places | $2,278 | -49.8% | 1 | - | $2,278 | $114,929 | 7 | Sharmill Films | false | false |
| 35 | 30 | 1408 | $2,277 | -16.5% | 12 | +9 | $189 | $2,592,564 | 7 | Roadshow Films | false | false |
| 36 | 32 | Michael Clayton | $567 | +16% | 2 | -4 | $283 | $3,074,682 | 14 | Roadshow Films | false | false |
| 37 | 34 | September | $525 | +15.9% | 2 | +1 | $262 | $56,521 | 8 | Hopscotch Films | false | false |
| 38 | - | Rogue | $414 | - | 3 | - | $138 | $1,572,808 | 11 | Roadshow Films | false | false |
| 39 | 24 | Rescue Dawn | $389 | -96.3% | 2 | -3 | $194 | $491,626 | 9 | Hopscotch Films | false | false |
| 40 | 33 | Fred Claus | $244 | -50.1% | 1 | -5 | $244 | $3,594,743 | 10 | Warner Bros. | false | false |
