| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | National Treasure: Book of Secrets | $414,359 | -23.3% | 77 | +2 | $5,381 | $2,206,768 | 3 | Walt Disney Pictures | false | false |
| 2 | - | Aliens vs. Predator: Requiem | $314,142 | - | 40 | - | $7,853 | $381,034 | 1 | 20th Century Fox International | true | false |
| 3 | - | Charlie Wilson's War | $216,703 | - | 32 | - | $6,771 | $223,738 | 1 | Universal Pictures International (UPI) | true | false |
| 4 | 2 | I Am Legend | $215,864 | -31.8% | 66 | - | $3,270 | $4,256,856 | 5 | Warner Bros. | false | false |
| 5 | 4 | Alvin and the Chipmunks | $187,179 | -1.2% | 71 | - | $2,636 | $1,695,234 | 5 | 20th Century Fox International | false | false |
| 6 | 3 | Atonement | $176,236 | -10% | 20 | - | $8,811 | $485,054 | 2 | Universal Pictures International (UPI) | false | false |
| 7 | 6 | Into the Wild | $120,440 | -21.6% | 13 | - | $9,264 | $301,975 | 2 | Alternative Films | false | false |
| 8 | 5 | Enchanted | $114,799 | -26.5% | 72 | -11 | $1,594 | $2,313,255 | 5 | Walt Disney Pictures | false | false |
| 9 | 8 | Bee Movie | $107,631 | -11.2% | 80 | -11 | $1,345 | $2,949,881 | 6 | Universal Pictures International (UPI) | false | false |
| 10 | 7 | The Golden Compass | $101,288 | -28.3% | 84 | -6 | $1,205 | $3,171,541 | 7 | Kinepolis Film Distribution (KFD) | false | false |
| 11 | - | The Masked Gang: Cyprus | $101,042 | - | 5 | - | $20,208 | $101,042 | 1 | Maxximum Film und Kunst GmbH | true | false |
| 12 | - | The Merry Widow | $100,023 | - | 17 | - | $5,883 | $100,023 | 1 | Victory Productions | true | false |
| 13 | 9 | 30 Days of Night | $69,274 | -40.1% | 30 | - | $2,309 | $199,768 | 2 | Benelux Film Distributors | false | false |
| 14 | 10 | Rendition | $66,141 | -38.5% | 24 | - | $2,755 | $199,423 | 2 | Kinepolis Film Distribution (KFD) | false | false |
| 15 | - | Before the Devil Knows You're Dead | $63,642 | - | 15 | - | $4,242 | $64,217 | 1 | Cinéart | true | false |
| 16 | 12 | K3 en de kattenprins | $57,726 | -22% | 31 | -5 | $1,862 | $876,874 | 5 | Kinepolis Film Distribution (KFD) | false | false |
| 17 | 11 | Saw IV | $51,476 | -48.6% | 32 | -2 | $1,608 | $1,050,536 | 4 | Les Films de l'Elysée | false | false |
| 18 | - | It's a Free World... | $50,797 | - | 14 | - | $3,628 | $65,244 | 1 | Cinéart | true | false |
| 19 | 13 | Gone Baby Gone | $47,184 | -29.6% | 31 | -7 | $1,522 | $550,151 | 4 | Walt Disney Pictures | false | false |
| 20 | 15 | Good Luck Chuck | $39,219 | -23.7% | 11 | - | $3,565 | $474,507 | 5 | Sony Pictures Releasing | false | false |
| 21 | 14 | Elizabeth: The Golden Age | $33,433 | -36.7% | 30 | -6 | $1,114 | $945,505 | 6 | Universal Pictures International (UPI) | false | false |
| 22 | 16 | American Gangster | $22,682 | -26.9% | 20 | +2 | $1,134 | $2,150,588 | 10 | Universal Pictures International (UPI) | false | false |
| 23 | - | The Unknown Woman | $16,543 | - | 9 | - | $1,838 | $18,177 | 1 | ABC Distribution | true | false |
| 24 | 21 | Mr. Magorium's Wonder Emporium | $14,791 | -12.7% | 18 | -4 | $821 | $213,598 | 4 | Benelux Film Distributors | false | false |
| 25 | 22 | Two Worlds | $14,778 | -10% | 5 | -3 | $2,955 | $854,327 | 9 | Benelux Film Distributors | false | false |
| 26 | 17 | Eastern Promises | $14,189 | -48.9% | 23 | +6 | $616 | $761,911 | 8 | Kinepolis Film Distribution (KFD) | false | false |
| 27 | 26 | The Secret of the Grain | $13,967 | -0.8% | 5 | - | $2,793 | $136,841 | 6 | Alternative Films | false | false |
| 28 | 24 | Killer Babes | $13,291 | -12.4% | 3 | - | $4,430 | $101,757 | 5 | N/A | false | false |
| 29 | 28 | The Fox and the Child | $12,775 | -4.6% | 15 | +2 | $851 | $193,232 | 6 | Paradiso Entertainment | false | false |
| 30 | 18 | Cassandra's Dream | $12,626 | -53.7% | 11 | -3 | $1,147 | $225,681 | 4 | Cinéart | false | false |
| 31 | 29 | Surviving with Wolves | $12,147 | -1.2% | 12 | -3 | $1,012 | $559,227 | 9 | Victory Productions | false | false |
| 32 | 27 | Missing Persons Unit | $11,760 | -13.9% | 10 | -5 | $1,176 | $1,940,217 | 12 | Kinepolis Film Distribution (KFD) | false | false |
| 33 | 23 | My Blueberry Nights | $11,701 | -26.4% | 15 | - | $780 | $332,798 | 7 | Cinéart | false | false |
| 34 | 25 | The Edge of Heaven | $11,615 | -18.8% | 8 | -1 | $1,451 | $321,612 | 10 | Cinéart | false | false |
| 35 | 35 | We Own the Night | $7,388 | -13.3% | 7 | +1 | $1,055 | $404,144 | 8 | Paradiso Entertainment | false | false |
| 36 | 33 | Ben X | $6,695 | -25% | 14 | -1 | $478 | $2,295,266 | 17 | Kinepolis Film Distribution (KFD) | false | false |
| 37 | 31 | Beowulf | $6,641 | -35.9% | 3 | -8 | $2,213 | $1,505,872 | 9 | Warner Bros. | false | false |
| 38 | 30 | Cow-Boy | $5,566 | -50.8% | 9 | -6 | $618 | $365,142 | 7 | Belga Films | false | false |
| 39 | 20 | Hitman | $5,379 | -70% | 7 | -20 | $768 | $991,615 | 8 | 20th Century Fox International | false | false |
| 40 | 34 | California Dreamin' | $4,425 | -48.3% | 6 | -1 | $737 | $15,755 | 2 | Benelux Film Distributors | false | false |
| 41 | - | The Killer | $3,972 | - | 3 | - | $1,324 | $5,637 | 1 | Les Films de l'Elysée | true | false |
| 42 | 39 | The Kingdom | $3,587 | -31.7% | 1 | -1 | $3,587 | $894,274 | 12 | Universal Pictures International (UPI) | false | false |
| 43 | 42 | Ratatouille | $3,515 | -12.8% | 2 | -1 | $1,757 | $8,907,128 | 25 | Buena Vista International | false | false |
| 44 | 44 | Underdog | $3,333 | +15.8% | 2 | -9 | $1,666 | $482,284 | 9 | Walt Disney Pictures | false | false |
| 45 | 40 | Mr. Brooks | $2,973 | -39.1% | 1 | - | $2,973 | $607,660 | 14 | Kinepolis Film Distribution (KFD) | false | false |
| 46 | 19 | Room of Death | $2,260 | -88.3% | 9 | -6 | $251 | $75,751 | 2 | Cinéart | false | false |
| 47 | 49 | Plop en de pinguïn | $2,253 | +12.3% | 2 | - | $1,126 | $1,059,110 | 14 | Kinepolis Film Distribution (KFD) | false | false |
| 48 | 51 | Rush Hour 3 | $1,861 | +21.8% | 1 | - | $1,861 | $1,538,289 | 14 | Paradiso Entertainment | false | false |
| 49 | 48 | Surf's Up | $1,767 | -14% | 3 | - | $589 | $859,623 | 13 | Sony Pictures Releasing | false | false |
| 50 | 50 | The Bourne Ultimatum | $1,763 | +3.9% | 2 | - | $881 | $3,099,590 | 19 | Universal Pictures International (UPI) | false | false |
| 51 | 45 | Silent Light | $1,150 | -55.7% | 4 | - | $287 | $21,906 | 7 | Benelux Film Distributors | false | false |
| 52 | 47 | The Grocer's Son | $1,083 | -48.5% | 4 | - | $270 | $65,298 | 8 | Benelux Film Distributors | false | false |
| 53 | 38 | The Return | $995 | -81.5% | 2 | -6 | $497 | $118,241 | 3 | Universal Pictures International (UPI) | false | false |
| 54 | 52 | You, the Living | $620 | -54.7% | 2 | -1 | $310 | $45,864 | 9 | Benelux Film Distributors | false | false |
| 55 | 53 | Control | $486 | -49.2% | 1 | -1 | $486 | $143,538 | 19 | Paradiso Entertainment | false | false |
