| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | 10,000 BC | $278,448 | -43.5% | 56 | +5 | $4,972 | $906,019 | 2 | Warner Bros. | false | false |
| 2 | - | Horton Hears a Who! | $241,831 | - | 92 | - | $2,628 | $241,831 | 1 | 20th Century Fox International | true | false |
| 3 | 2 | No Country for Old Men | $125,233 | -44.9% | 40 | - | $3,130 | $408,389 | 2 | Walt Disney Pictures | false | false |
| 4 | - | The Orphanage | $103,901 | - | 33 | - | $3,148 | $103,901 | 1 | CDI Films | true | false |
| 5 | 3 | The Bucket List | $90,229 | -26.5% | 58 | +2 | $1,555 | $1,518,339 | 6 | Warner Bros. | false | false |
| 6 | 6 | Death at a Funeral | $73,180 | +15.4% | 16 | +2 | $4,573 | $158,727 | 2 | - | false | false |
| 7 | 4 | The Game Plan | $52,881 | -52.6% | 45 | -3 | $1,175 | $1,160,700 | 5 | Walt Disney Pictures | false | false |
| 8 | 5 | Vantage Point | $34,492 | -49.8% | 38 | -8 | $907 | $315,879 | 3 | Sony Pictures Releasing | false | false |
| 9 | 7 | P.S. I Love You | $34,205 | -38.8% | 29 | +1 | $1,179 | $233,453 | 3 | Alfa Films | false | false |
| 10 | - | Elizabeth: The Golden Age | $26,059 | - | 10 | - | $2,605 | $26,059 | 1 | United International Pictures | true | false |
| 11 | 10 | The Eye | $25,128 | -34.3% | 24 | +3 | $1,047 | $172,344 | 3 | United International Pictures | false | false |
| 12 | 8 | There Will Be Blood | $24,376 | -51.5% | 35 | - | $696 | $436,785 | 4 | Walt Disney Pictures | false | false |
| 13 | 9 | Juno | $22,378 | -52.4% | 22 | -13 | $1,017 | $412,456 | 5 | Alfa Films | false | false |
| 14 | 18 | Fool's Gold | $16,682 | -2.8% | 22 | +3 | $758 | $92,434 | 3 | Warner Bros. | false | false |
| 15 | 20 | Atonement | $15,692 | +4.6% | 18 | +2 | $871 | $462,694 | 6 | United International Pictures | false | false |
| 16 | 12 | Sweeney Todd: The Demon Barber of Fleet Street | $14,996 | -57.1% | 35 | -8 | $428 | $632,284 | 5 | Warner Bros. | false | false |
| 17 | 11 | 3:10 to Yuma | $13,543 | -63.8% | 20 | -12 | $677 | $190,630 | 3 | Distribution Company | false | false |
| 18 | - | Angel-A | $12,082 | - | 10 | - | $1,208 | $12,082 | 1 | Distribution Company | true | false |
| 19 | 13 | The Water Horse | $11,815 | -64% | 29 | - | $407 | $541,706 | 6 | Sony Pictures Releasing | false | false |
| 20 | 15 | Love in the Time of Cholera | $10,987 | -42.1% | 23 | -4 | $477 | $564,886 | 9 | 20th Century Fox International | false | false |
| 21 | 24 | Away from Her | $10,644 | -1.7% | 17 | +2 | $626 | $151,483 | 4 | Distribution Company | false | false |
| 22 | 14 | Eastern Promises | $10,103 | -63.5% | 20 | -15 | $505 | $409,292 | 5 | Distribution Company | false | false |
| 23 | 16 | Cloverfield | $7,283 | -60.5% | 16 | -12 | $455 | $623,418 | 6 | United International Pictures | false | false |
| 24 | 22 | An American Haunting | $7,159 | -45% | 14 | -14 | $511 | $514,820 | 7 | Distribution Company | false | false |
| 25 | 23 | Charlie Wilson's War | $6,242 | -44.4% | 16 | -3 | $390 | $842,421 | 8 | United International Pictures | false | false |
| 26 | 21 | Explosive Brigade: Pirate Mission | $5,731 | -60.7% | 22 | -10 | $260 | $754,054 | 7 | Argentina Sono Film S.A.C.I. | false | false |
| 27 | 19 | Rambo | $5,711 | -66.2% | 17 | -8 | $335 | $295,962 | 4 | CDI Films | false | false |
| 28 | 17 | Martian Child | $2,776 | -84.2% | 7 | -13 | $396 | $26,015 | 2 | Distribution Company | false | false |
| 29 | 37 | 1408 | $2,199 | +57.9% | 5 | +1 | $439 | $234,535 | 8 | United International Pictures | false | false |
| 30 | 31 | The Wayward Cloud 2007 Re-release | $2,127 | -37.7% | 2 | - | $1,063 | $16,543 | 3 | 791 Cine | false | false |
| 31 | 34 | Possible Lives | $2,090 | -4.5% | 5 | - | $418 | $16,968 | 6 | Primer Plano Film Group | false | false |
| 32 | 25 | 27 Dresses | $1,778 | -76.1% | 6 | -17 | $296 | $283,756 | 6 | 20th Century Fox International | false | false |
| 33 | 36 | Hannibal Rising | $1,705 | +0.7% | 5 | -1 | $341 | $77,650 | 4 | United International Pictures | false | false |
| 34 | 29 | Enchanted | $1,246 | -64.2% | 15 | -10 | $83 | $2,788,220 | 11 | Walt Disney Pictures | false | false |
| 35 | 26 | Sleuth | $1,191 | -76.6% | 3 | -7 | $397 | $165,053 | 10 | Sony Pictures Releasing | false | false |
| 36 | 28 | Aliens vs. Predator: Requiem | $829 | -77.6% | 9 | -7 | $92 | $690,481 | 10 | 20th Century Fox International | false | false |
| 37 | 40 | La Vie En Rose | $765 | -7.2% | 2 | - | $382 | $500,339 | 45 | Alfa Films | false | false |
| 38 | 32 | National Treasure: Book of Secrets | $704 | -75.5% | 11 | -10 | $64 | $1,659,490 | 9 | Walt Disney Pictures | false | false |
| 39 | 33 | Gone Baby Gone | $689 | -74% | 3 | -3 | $229 | $422,342 | 17 | Walt Disney Pictures | false | false |
| 40 | 35 | Hitman | $647 | -61.9% | 2 | -10 | $323 | $182,414 | 8 | 20th Century Fox International | false | false |
| 41 | 27 | Alvin and the Chipmunks | $498 | -87.8% | 8 | -19 | $62 | $793,167 | 11 | 20th Century Fox International | false | false |
| 42 | - | The Assassination of Jesse James by the Coward Robert Ford | $482 | - | 1 | - | $482 | $158,043 | 16 | Warner Bros. | false | false |
| 43 | 39 | Bridge to Terabithia | $438 | -49% | 4 | +1 | $109 | $100,082 | 10 | United International Pictures | false | false |
| 44 | 44 | The Golden Compass | $308 | -40.5% | 4 | - | $77 | $1,386,364 | 14 | Distribution Company | false | false |
| 45 | 45 | Michael Clayton | $257 | -39% | 2 | - | $128 | $578,107 | 23 | Alfa Films | false | false |
| 46 | 59 | Bratz | $250 | +410.2% | 2 | - | $125 | $43,925 | 5 | Pachamama Cine | false | false |
| 47 | 46 | Giants of Valdes | $229 | -24.4% | 2 | - | $114 | $82,570 | 9 | Primer Plano Film Group | false | false |
| 48 | 53 | 4 Months, 3 Weeks and 2 Days | $223 | +68.9% | 2 | +1 | $111 | $203,767 | 15 | Pachamama Cine | false | false |
| 49 | 47 | Bee Movie | $222 | -12.3% | 4 | +1 | $55 | $1,468,617 | 15 | United International Pictures | false | false |
| 50 | 51 | The Heartbreak Kid | $215 | +31.9% | 1 | -1 | $215 | $914,034 | 19 | United International Pictures | false | false |
| 51 | 52 | Tres minutos | $178 | +33.8% | 2 | - | $89 | $6,518 | 4 | Primer Plano Film Group | false | false |
| 52 | - | Open Season | $169 | - | 1 | - | $169 | $556,192 | 76 | Sony Pictures Releasing | false | false |
| 53 | 43 | I Am Legend | $167 | -68.7% | 5 | -1 | $33 | $2,078,611 | 12 | Warner Bros. | false | false |
| 54 | 42 | The Cave of the Yellow Dog 2008 Re-release | $117 | -80.6% | 1 | -1 | $117 | $29,703 | 7 | IFA | false | false |
| 55 | 54 | Encarnacion | $102 | -15.7% | 1 | - | $102 | $41,526 | 23 | Distribution Company | false | false |
| 56 | 55 | Beowulf | $42 | -64.4% | 1 | -1 | $42 | $705,766 | 17 | Warner Bros. | false | false |
| 57 | 60 | Whisper | $31 | -18.4% | 1 | - | $31 | $112,121 | 16 | Alfa Films | false | false |
| 58 | 56 | Underdog | $23 | -68.5% | 1 | -1 | $23 | $849,416 | 24 | Walt Disney Pictures | false | false |
