| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | 10,000 BC | $156,789 | -30.3% | 35 | +1 | $4,479 | $868,118 | 3 | Warner Bros. | false | false |
| 2 | 2 | Horton Hears a Who! | $113,102 | -36.2% | 40 | - | $2,827 | $320,496 | 2 | 20th Century Fox International | false | false |
| 3 | - | Mirageman | $106,612 | - | 25 | - | $4,264 | $106,612 | 1 | Bazuca Films | true | false |
| 4 | - | The Spiderwick Chronicles | $82,438 | - | 31 | - | $2,659 | $82,438 | 1 | United International Pictures | true | false |
| 5 | 3 | In the Valley of Elah | $40,342 | -11.6% | 15 | - | $2,689 | $97,140 | 2 | Bazuca Films | false | false |
| 6 | 4 | One Missed Call | $24,626 | -32.5% | 15 | -2 | $1,641 | $230,766 | 4 | Warner Bros. | false | false |
| 7 | 5 | No Country for Old Men | $24,344 | -24.9% | 10 | -1 | $2,434 | $344,391 | 6 | United International Pictures | false | false |
| 8 | 7 | Juno | $18,098 | -17% | 7 | -3 | $2,585 | $211,643 | 5 | Bazuca Films | false | false |
| 9 | 8 | The Bucket List | $17,139 | -19.4% | 8 | -3 | $2,142 | $501,310 | 8 | Warner Bros. | false | false |
| 10 | 11 | P.S. I Love You | $16,760 | -18% | 10 | -2 | $1,676 | $287,352 | 6 | Bazuca Films | false | false |
| 11 | 6 | American Gangster | $16,258 | -41.4% | 17 | -8 | $956 | $230,784 | 4 | United International Pictures | false | false |
| 12 | 10 | Hannah Montana and Miley Cyrus: Best of Both Worlds Concert | $15,938 | -22.4% | 1 | - | $15,938 | $111,118 | 4 | Walt Disney Pictures | false | false |
| 13 | 9 | The Water Horse | $14,319 | -30.7% | 20 | -5 | $715 | $592,017 | 7 | Sony Pictures Releasing | false | false |
| 14 | 12 | The Game Plan | $11,341 | -37.3% | 16 | -3 | $708 | $983,393 | 10 | Walt Disney Pictures | false | false |
| 15 | 13 | Atonement | $10,418 | -40.4% | 6 | -3 | $1,736 | $243,643 | 6 | United International Pictures | false | false |
| 16 | 15 | There Will Be Blood | $8,064 | -36.8% | 7 | -2 | $1,152 | $175,142 | 5 | Walt Disney Pictures | false | false |
| 17 | 16 | Sweeney Todd: The Demon Barber of Fleet Street | $6,314 | -42.3% | 13 | -3 | $485 | $483,489 | 7 | Warner Bros. | false | false |
| 18 | 14 | Halloween | $5,210 | -60% | 9 | -2 | $578 | $22,464 | 2 | Transeuropa | false | false |
| 19 | 18 | Persepolis | $3,453 | +12.5% | 1 | - | $3,453 | $7,654 | 2 | Sony Pictures Releasing | false | false |
| 20 | 17 | The Hitcher | $2,971 | -29.2% | 3 | - | $990 | $55,220 | 4 | Bazuca Films | false | false |
| 21 | 19 | The Education of Fairies | $1,696 | -38.4% | 1 | - | $1,696 | $5,005 | 2 | Walt Disney Pictures | false | false |
| 22 | 21 | Hannibal Rising | $1,664 | -23.6% | 3 | - | $554 | $87,429 | 8 | United International Pictures | false | false |
| 23 | - | Microfilia | $1,650 | - | 8 | - | $206 | $11,422 | 2 | - | false | false |
| 24 | 20 | Cloverfield | $1,089 | -59.9% | 4 | -2 | $272 | $413,456 | 7 | United International Pictures | false | false |
| 25 | 23 | Love in the Time of Cholera | $641 | -43.3% | 1 | -2 | $641 | $369,237 | 10 | 20th Century Fox International | false | false |
| 26 | 26 | Enchanted | $468 | -7.3% | 2 | -2 | $234 | $1,426,461 | 15 | Walt Disney Pictures | false | false |
| 27 | 22 | Noah's Ark | $378 | -82.4% | 1 | -7 | $378 | $92,252 | 5 | Walt Disney Pictures | false | false |
| 28 | - | Casino Royale | $190 | - | 1 | - | $190 | $807,785 | 68 | Sony Pictures Releasing | false | false |
