| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Spiderwick Chronicles | $919,790 | -28.1% | 269 | +2 | $3,419 | $3,632,312 | 2 | Paramount Pictures International | false | false |
| 2 | - | Superhero Movie | $918,205 | - | 188 | - | $4,884 | $918,586 | 1 | Roadshow Films | true | false |
| 3 | - | Prom Night | $854,514 | - | 123 | - | $6,947 | $854,514 | 1 | Sony Pictures Releasing | true | false |
| 4 | 6 | Nim's Island | $779,860 | +37.8% | 196 | +101 | $3,978 | $1,690,569 | 2 | Universal Pictures International (UPI) | false | false |
| 5 | 2 | Semi-Pro | $672,079 | -47.4% | 202 | - | $3,327 | $2,443,561 | 2 | Roadshow Films | false | false |
| 6 | 3 | Horton Hears a Who! | $669,302 | -29.4% | 303 | -54 | $2,208 | $7,817,201 | 4 | 20th Century Fox International | false | false |
| 7 | 4 | Step Up 2: The Streets | $468,457 | -42.1% | 183 | -5 | $2,559 | $7,062,415 | 4 | Universal Pictures International (UPI) | false | false |
| 8 | 5 | Never Back Down | $332,356 | -46% | 146 | -5 | $2,276 | $2,409,171 | 3 | Roadshow Films | false | false |
| 9 | - | U2 3D | $274,260 | - | 23 | - | $11,924 | $274,260 | 1 | Roadshow Films | true | false |
| 10 | 7 | St. Trinian's | $273,008 | -45.1% | 207 | -2 | $1,318 | $1,921,986 | 3 | Sony Pictures Releasing | false | false |
| 11 | 10 | The Other Boleyn Girl | $207,049 | -30.4% | 105 | -27 | $1,971 | $3,293,486 | 5 | Universal Pictures International (UPI) | false | false |
| 12 | 9 | Vantage Point | $180,060 | -41.6% | 83 | -77 | $2,169 | $3,895,335 | 5 | Sony Pictures Releasing | false | false |
| 13 | 13 | Before the Devil Knows You're Dead | $170,154 | +3.4% | 35 | +13 | $4,861 | $934,227 | 4 | Hopscotch Films | false | false |
| 14 | 8 | Drillbit Taylor | $163,368 | -57.6% | 174 | -20 | $938 | $3,503,804 | 4 | Paramount Pictures International | false | false |
| 15 | - | How She Move | $153,209 | - | 100 | - | $1,532 | $153,209 | 1 | Paramount Pictures International | true | false |
| 16 | 15 | Lars and the Real Girl | $142,963 | +17.3% | 17 | - | $8,409 | $314,664 | 2 | Rialto Distribution | false | false |
| 17 | 11 | The Bucket List | $131,575 | -26.8% | 107 | -21 | $1,229 | $7,000,794 | 8 | Warner Bros. | false | false |
| 18 | 14 | The Black Balloon | $122,534 | -11.8% | 74 | -2 | $1,655 | $1,500,299 | 6 | Icon Film Distribution | false | false |
| 19 | - | Paris | $97,082 | - | 29 | - | $3,347 | $97,082 | 1 | Icon Film Distribution | true | false |
| 20 | 12 | 10,000 BC | $65,386 | -61.8% | 62 | -78 | $1,054 | $5,948,655 | 6 | Warner Bros. | false | false |
| 21 | 16 | Be Kind Rewind | $65,347 | -33.1% | 36 | -5 | $1,815 | $732,224 | 4 | Roadshow Films | false | false |
| 22 | 18 | Brick Lane | $62,159 | -17.1% | 25 | +4 | $2,486 | $437,702 | 4 | Madman Entertainment | false | false |
| 23 | - | U Me Aur Hum | $55,780 | - | 8 | - | $6,972 | $55,780 | 1 | Eros Worldwide | true | false |
| 24 | 21 | No Country for Old Men | $43,434 | -13% | 41 | -7 | $1,059 | $5,753,072 | 16 | Paramount Pictures International | false | false |
| 25 | 22 | The Kite Runner | $36,865 | -16.1% | 30 | -5 | $1,228 | $2,623,386 | 13 | Paramount Pictures International | false | false |
| 26 | - | The Secret of the Grain | $34,476 | - | 14 | - | $2,462 | $289,083 | 4 | Palace Films | false | false |
| 27 | 17 | The Eye | $26,018 | -68.5% | 28 | -21 | $929 | $1,380,503 | 5 | Paramount Pictures International | false | false |
| 28 | 25 | There Will Be Blood | $24,201 | -34.7% | 34 | -4 | $711 | $2,358,612 | 10 | Walt Disney Pictures | false | false |
| 29 | 39 | In the Valley of Elah | $24,098 | +219.6% | 14 | +3 | $1,721 | $488,667 | 7 | Hoyts Distribution | false | false |
| 30 | 20 | Hannah Montana and Miley Cyrus: Best of Both Worlds Concert | $23,222 | -58.8% | 20 | - | $1,161 | $1,041,448 | 4 | Walt Disney Pictures | false | false |
| 31 | 23 | Run Fatboy Run | $21,129 | -48.3% | 26 | -17 | $812 | $3,058,823 | 6 | Roadshow Films | false | false |
| 32 | - | Krazzy 4 | $20,807 | - | 5 | - | $4,161 | $20,807 | 1 | Eros Worldwide | true | false |
| 33 | 26 | Juno | $20,021 | -33.4% | 36 | -29 | $556 | $10,813,936 | 13 | 20th Century Fox International | false | false |
| 34 | 27 | The Diving Bell and the Butterfly | $18,681 | -24.3% | 26 | -1 | $718 | $954,595 | 9 | Icon Film Distribution | false | false |
| 35 | 28 | In the Shadow of the Moon | $17,220 | -20.3% | 18 | - | $956 | $325,362 | 6 | Madman Entertainment | false | false |
| 36 | 32 | L'invité | $14,443 | -10.3% | 15 | - | $962 | $247,584 | 4 | Dendy Films | false | false |
| 37 | 19 | Hey Hey It's Esther Blueburger | $14,290 | -77% | 53 | -81 | $269 | $755,080 | 4 | Walt Disney Pictures | false | false |
| 38 | 37 | Closing the Ring | $10,209 | +10.7% | 21 | +5 | $486 | $294,353 | 6 | Hopscotch Films | false | false |
| 39 | 40 | Meet the Spartans | $9,878 | +35.7% | 16 | -1 | $617 | $2,771,188 | 7 | 20th Century Fox International | false | false |
| 40 | 38 | Sweeney Todd: The Demon Barber of Fleet Street | $7,958 | -12.4% | 15 | -5 | $530 | $5,089,215 | 12 | Warner Bros. | false | false |
| 41 | 31 | Jumper | $7,542 | -55.3% | 15 | -12 | $502 | $8,301,391 | 9 | 20th Century Fox International | false | false |
| 42 | 45 | Lust, Caution | $7,542 | +53.3% | 6 | -2 | $1,257 | $784,518 | 13 | Park Circus | false | false |
| 43 | 46 | Bella | $6,415 | +40.4% | 9 | +3 | $712 | $183,319 | 8 | Hopscotch Films | false | false |
| 44 | - | Global Haywire | $5,435 | - | 3 | - | $1,811 | $7,742 | 1 | Hopscotch Films | true | false |
| 45 | 30 | Race | $4,596 | -74% | 6 | -8 | $766 | $326,299 | 4 | MG Distribution | false | false |
| 46 | 43 | Grindhouse | $4,505 | -30.4% | 2 | - | $2,252 | $99,896 | 18 | Roadshow Films | false | false |
| 47 | 44 | Fool's Gold | $3,770 | -35.4% | 11 | -5 | $342 | $4,945,729 | 10 | Warner Bros. | false | false |
| 48 | - | Death Defying Acts | $3,391 | - | 7 | - | $484 | $647,983 | 5 | Dendy Films | false | false |
| 49 | 51 | Paranoid Park | $1,973 | -2.5% | 2 | -1 | $986 | $52,980 | 6 | Madman Entertainment | false | false |
| 50 | 52 | Two Days in Paris | $1,413 | -25.4% | 3 | -1 | $471 | $1,678,851 | 16 | Hopscotch Films | false | false |
| 51 | 53 | 3:10 to Yuma | $1,218 | -31.4% | 6 | -4 | $203 | $2,371,873 | 11 | Hoyts Distribution | false | false |
| 52 | - | August Rush | $729 | - | 3 | - | $243 | $630,942 | 8 | Magna Pacific | false | false |
| 53 | - | After Him | $682 | - | 3 | - | $227 | $60,443 | 3 | Palace Films | false | false |
| 54 | 56 | Rendition | $332 | -15.7% | 4 | +1 | $83 | $430,491 | 9 | Roadshow Films | false | false |
