| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Iron Man | $527,314 | - | 41 | - | $12,861 | $592,630 | 1 | United International Pictures | true | false |
| 2 | - | The Orphanage | $99,799 | - | 16 | - | $6,237 | $99,799 | 1 | CDI Films | true | false |
| 3 | 1 | 31 Minutos: La Película | $85,630 | +17.6% | 37 | - | $2,314 | $1,044,709 | 6 | MC Film | false | false |
| 4 | 4 | An American Haunting | $71,202 | +42.7% | 18 | +2 | $3,955 | $208,885 | 3 | Bazuca Films | false | false |
| 5 | 2 | Lokas | $56,605 | +2.8% | 36 | - | $1,572 | $585,987 | 5 | Andes Films | false | false |
| 6 | 3 | Meet the Spartans | $41,350 | -23% | 23 | +1 | $1,797 | $107,037 | 2 | 20th Century Fox International | false | false |
| 7 | 7 | The Spiderwick Chronicles | $39,427 | +16.9% | 19 | -7 | $2,075 | $403,298 | 7 | United International Pictures | false | false |
| 8 | 5 | Shutter | $34,439 | -16% | 21 | +3 | $1,639 | $154,138 | 3 | 20th Century Fox International | false | false |
| 9 | 6 | Vantage Point | $34,392 | -12.8% | 12 | -15 | $2,866 | $231,530 | 4 | Sony Pictures Releasing | false | false |
| 10 | 8 | Eastern Promises | $32,509 | -0.2% | 14 | -4 | $2,322 | $187,472 | 4 | Bazuca Films | false | false |
| 11 | 9 | Horton Hears a Who! | $31,273 | +14.5% | 31 | -3 | $1,008 | $587,883 | 8 | 20th Century Fox International | false | false |
| 12 | - | Lassie | $26,522 | - | 12 | - | $2,210 | $26,522 | 1 | Bazuca Films | true | false |
| 13 | - | August Rush | $26,522 | - | 12 | - | $2,210 | $26,522 | 1 | Bazuca Films | true | false |
| 14 | - | U2 3D | $10,187 | - | 1 | - | $10,187 | $10,187 | 1 | N/A | true | false |
| 15 | 10 | Mansacue | $8,904 | -61.5% | 18 | -2 | $494 | $38,161 | 2 | N/A | false | false |
| 16 | 18 | The Eye | $8,809 | +16.1% | 12 | -7 | $734 | $90,150 | 4 | United International Pictures | false | false |
| 17 | 11 | Jumper | $8,770 | -55.2% | 9 | -14 | $974 | $378,994 | 6 | 20th Century Fox International | false | false |
| 18 | 13 | Mirageman | $8,761 | -40.6% | 9 | -5 | $973 | $386,909 | 7 | Bazuca Films | false | false |
| 19 | 20 | After the Wedding | $8,370 | +34.1% | 4 | +1 | $2,092 | $63,143 | 6 | Transeuropa | false | false |
| 20 | 16 | The Darjeeling Limited | $7,597 | -19.1% | 4 | - | $1,899 | $65,756 | 5 | 20th Century Fox International | false | false |
| 21 | 14 | Fool's Gold | $7,231 | -38.2% | 6 | -15 | $1,205 | $82,134 | 4 | Warner Bros. | false | false |
| 22 | 15 | 10,000 BC | $3,330 | -68% | 7 | -14 | $475 | $1,220,076 | 9 | Warner Bros. | false | false |
| 23 | 17 | Rambo | $2,936 | -65.1% | 12 | -10 | $244 | $153,729 | 5 | N/A | false | false |
| 24 | 23 | In the Valley of Elah | $2,731 | -3.9% | 5 | -4 | $546 | $178,131 | 8 | Bazuca Films | false | false |
| 25 | 26 | The Game Plan | $2,608 | +58.1% | 3 | - | $869 | $985,551 | 16 | Walt Disney Pictures | false | false |
| 26 | 12 | Whisper | $2,406 | -84.4% | 10 | -2 | $240 | $20,671 | 2 | Transeuropa | false | false |
| 27 | 22 | Atonement | $2,166 | -24.1% | 3 | - | $722 | $268,824 | 12 | United International Pictures | false | false |
| 28 | 27 | P.S. I Love You | $872 | -42.1% | 3 | +1 | $290 | $307,491 | 12 | Bazuca Films | false | false |
| 29 | 29 | The Bucket List | $759 | +39.5% | 1 | -1 | $759 | $518,472 | 14 | Warner Bros. | false | false |
| 30 | 19 | Mr. Woodcock | $718 | -90.1% | 5 | -7 | $143 | $26,703 | 3 | Bazuca Films | false | false |
| 31 | 30 | The Water Horse | $601 | +23.9% | 1 | - | $601 | $600,194 | 13 | Sony Pictures Releasing | false | false |
| 32 | 24 | No Country for Old Men | $431 | -80.3% | 5 | -4 | $86 | $381,610 | 12 | United International Pictures | false | false |
