| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Iron Man | $185,405 | -64.8% | 39 | -2 | $4,753 | $892,135 | 2 | United International Pictures | false | false |
| 2 | - | Speed Racer | $152,297 | - | 39 | - | $3,905 | $152,297 | 1 | Warner Bros. | true | false |
| 3 | 2 | The Orphanage | $74,063 | -25.8% | 16 | - | $4,628 | $204,291 | 2 | CDI Films | false | false |
| 4 | - | Charlie Wilson's War | $50,311 | - | 21 | - | $2,395 | $50,311 | 1 | United International Pictures | true | false |
| 5 | 4 | An American Haunting | $36,657 | -48.5% | 16 | -2 | $2,291 | $259,171 | 4 | Bazuca Films | false | false |
| 6 | 3 | 31 Minutos: La Película | $22,653 | -73.5% | 38 | +1 | $596 | $1,075,900 | 7 | MC Film | false | false |
| 7 | 5 | Lokas | $21,472 | -62.1% | 15 | -21 | $1,431 | $618,795 | 6 | Andes Films | false | false |
| 8 | 10 | Eastern Promises | $14,249 | -56.2% | 14 | - | $1,017 | $208,303 | 5 | Bazuca Films | false | false |
| 9 | 9 | Vantage Point | $13,793 | -59.9% | 12 | - | $1,149 | $251,024 | 5 | Sony Pictures Releasing | false | false |
| 10 | 8 | Shutter | $13,628 | -60.4% | 19 | -2 | $717 | $176,021 | 4 | 20th Century Fox International | false | false |
| 11 | 7 | The Spiderwick Chronicles | $13,097 | -66.8% | 21 | +2 | $623 | $419,842 | 8 | United International Pictures | false | false |
| 12 | 6 | Meet the Spartans | $10,224 | -75.3% | 24 | +1 | $426 | $124,579 | 3 | 20th Century Fox International | false | false |
| 13 | 13 | August Rush | $7,926 | -70.1% | 18 | +6 | $440 | $46,939 | 2 | Bazuca Films | false | false |
| 14 | 11 | Horton Hears a Who! | $7,718 | -75.3% | 22 | -9 | $350 | $596,871 | 9 | 20th Century Fox International | false | false |
| 15 | 12 | Lassie | $6,855 | -74.2% | 13 | +1 | $527 | $37,717 | 2 | Bazuca Films | false | false |
| 16 | - | The Page Turner | $5,326 | - | 2 | - | $2,663 | $5,326 | 1 | Four Films | true | false |
| 17 | 16 | The Eye | $4,330 | -50.8% | 9 | -3 | $481 | $97,408 | 5 | United International Pictures | false | false |
| 18 | 14 | U2 3D | $4,120 | -59.6% | 1 | - | $4,120 | $18,864 | 2 | N/A | false | false |
| 19 | 20 | The Darjeeling Limited | $3,211 | -57.7% | 3 | -1 | $1,070 | $74,146 | 6 | 20th Century Fox International | false | false |
| 20 | 19 | After the Wedding | $2,429 | -71% | 2 | -2 | $1,214 | $66,012 | 7 | Transeuropa | false | false |
| 21 | 21 | Fool's Gold | $2,207 | -69.5% | 3 | -3 | $735 | $85,487 | 5 | Warner Bros. | false | false |
| 22 | 18 | Mirageman | $1,534 | -82.5% | 3 | -6 | $511 | $390,003 | 8 | Bazuca Films | false | false |
| 23 | 24 | In the Valley of Elah | $1,188 | -56.5% | 3 | -2 | $396 | $179,931 | 9 | Bazuca Films | false | false |
| 24 | 22 | 10,000 BC | $889 | -73.3% | 4 | -3 | $222 | $1,222,724 | 10 | Warner Bros. | false | false |
| 25 | 25 | The Game Plan | $665 | -74.5% | 3 | - | $221 | $986,402 | 17 | Walt Disney Pictures | false | false |
| 26 | 27 | Atonement | $649 | -70% | 3 | - | $216 | $270,144 | 13 | United International Pictures | false | false |
| 27 | 17 | Jumper | $550 | -93.7% | 3 | -6 | $183 | $394,341 | 7 | 20th Century Fox International | false | false |
| 28 | 23 | Rambo | $255 | -91.3% | 6 | -6 | $42 | $154,770 | 6 | N/A | false | false |
| 29 | 31 | The Water Horse | $148 | -75.4% | 1 | - | $148 | $600,376 | 14 | Sony Pictures Releasing | false | false |
| 30 | 29 | The Bucket List | $147 | -80.6% | 1 | - | $147 | $518,715 | 15 | Warner Bros. | false | false |
| 31 | 15 | Mansacue | $128 | -98.6% | 15 | -3 | $8 | $41,091 | 3 | N/A | false | false |
