| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Chronicles of Narnia: Prince Caspian | $539,888 | - | 71 | - | $7,604 | $569,250 | 1 | Walt Disney Pictures | true | false |
| 2 | 1 | Iron Man | $141,439 | -23.7% | 38 | -1 | $3,722 | $1,121,428 | 3 | United International Pictures | false | false |
| 3 | 2 | Speed Racer | $140,303 | -7.9% | 40 | +1 | $3,507 | $354,839 | 2 | Warner Bros. | false | false |
| 4 | 3 | The Orphanage | $78,209 | +5.6% | 16 | - | $4,888 | $297,373 | 3 | CDI Films | false | false |
| 5 | 4 | Charlie Wilson's War | $40,476 | -19.5% | 20 | -1 | $2,023 | $115,363 | 2 | United International Pictures | false | false |
| 6 | 5 | An American Haunting | $35,034 | -4.4% | 15 | -1 | $2,335 | $311,972 | 5 | Bazuca Films | false | false |
| 7 | - | Elizabeth: The Golden Age | $17,503 | - | 4 | - | $4,375 | $17,503 | 1 | United International Pictures | true | false |
| 8 | - | Bordertown | $14,640 | - | 12 | - | $1,220 | $14,640 | 1 | Bazuca Films | true | false |
| 9 | 8 | Eastern Promises | $13,491 | -5.3% | 10 | -4 | $1,349 | $228,714 | 6 | Bazuca Films | false | false |
| 10 | 10 | Shutter | $9,871 | -27.6% | 7 | -12 | $1,410 | $195,869 | 5 | 20th Century Fox International | false | false |
| 11 | 6 | 31 Minutos: La Película | $8,640 | -61.9% | 12 | -26 | $720 | $1,093,409 | 8 | MC Film | false | false |
| 12 | 7 | Lokas | $8,341 | -61.2% | 7 | -8 | $1,191 | $636,938 | 7 | Andes Films | false | false |
| 13 | 18 | U2 3D | $7,264 | +76.3% | 1 | - | $7,264 | $30,758 | 3 | N/A | false | false |
| 14 | 9 | Vantage Point | $7,071 | -48.7% | 4 | -8 | $1,767 | $263,147 | 6 | Sony Pictures Releasing | false | false |
| 15 | 11 | The Spiderwick Chronicles | $7,035 | -46.3% | 6 | -15 | $1,172 | $439,982 | 9 | United International Pictures | false | false |
| 16 | 16 | The Page Turner | $6,239 | +17.1% | 2 | - | $3,119 | $12,963 | 2 | Four Films | false | false |
| 17 | 14 | Horton Hears a Who! | $5,896 | -23.6% | 9 | -13 | $655 | $609,140 | 10 | 20th Century Fox International | false | false |
| 18 | 12 | Meet the Spartans | $5,734 | -43.9% | 7 | -17 | $819 | $137,598 | 4 | 20th Century Fox International | false | false |
| 19 | 13 | August Rush | $2,423 | -69.4% | 3 | -15 | $807 | $53,751 | 3 | Bazuca Films | false | false |
| 20 | 17 | The Eye | $2,309 | -46.7% | 3 | -6 | $769 | $102,278 | 6 | United International Pictures | false | false |
| 21 | 20 | After the Wedding | $1,527 | -37.1% | 1 | -1 | $1,527 | $68,454 | 8 | Transeuropa | false | false |
| 22 | 31 | Mansacue | $1,322 | +932.8% | 4 | -11 | $330 | $42,811 | 4 | N/A | false | false |
| 23 | 15 | Lassie | $682 | -90.1% | 1 | -12 | $682 | $40,359 | 3 | Bazuca Films | false | false |
| 24 | 21 | Fool's Gold | $636 | -71.2% | 1 | -2 | $636 | $86,500 | 6 | Warner Bros. | false | false |
| 25 | - | Whisper | $508 | - | 1 | - | $508 | $21,594 | 4 | Transeuropa | false | false |
| 26 | 26 | Atonement | $470 | -27.6% | 1 | -2 | $470 | $271,072 | 14 | United International Pictures | false | false |
| 27 | 25 | The Game Plan | $448 | -32.6% | 2 | -1 | $224 | $986,937 | 18 | Walt Disney Pictures | false | false |
| 28 | - | The Flock | $111 | - | 1 | - | $111 | $25,066 | 6 | CDI Films | false | false |
