| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | What Happens in Vegas | $23,086 | +4.6% | 3 | - | $7,695 | $63,061 | 2 | N/A | false | false |
| 2 | 2 | Iron Man | $8,207 | -22.4% | 3 | - | $2,735 | $63,161 | 3 | N/A | false | false |
| 3 | - | Speed Racer | $4,988 | - | 3 | - | $1,662 | $4,988 | 1 | N/A | true | false |
| 4 | - | Baby Mama | $4,132 | - | 1 | - | $4,132 | $4,132 | 1 | N/A | true | false |
| 5 | 3 | Made of Honor | $3,601 | -8.5% | 2 | - | $1,800 | $30,308 | 3 | N/A | false | false |
| 6 | 4 | Forgetting Sarah Marshall | $3,334 | +19.7% | 2 | - | $1,667 | $46,220 | 4 | N/A | false | false |
| 7 | 7 | The Bucket List | $3,266 | +64.2% | 1 | - | $3,266 | $39,691 | 5 | N/A | false | false |
| 8 | 6 | Deception | $2,584 | +27.9% | 1 | -1 | $2,584 | $6,771 | 2 | N/A | false | false |
| 9 | 8 | The Ruins | $2,273 | +20.1% | 1 | - | $2,273 | $30,274 | 5 | N/A | false | false |
| 10 | 5 | 21 | $1,491 | -39.9% | 1 | - | $1,491 | $40,689 | 5 | N/A | false | false |
| 11 | 10 | Shutter | $1,125 | -19.7% | 1 | - | $1,125 | $20,032 | 4 | N/A | false | false |
