| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Indiana Jones and the Kingdom of the Crystal Skull | $483,914 | - | 40 | - | $12,097 | $483,914 | 1 | United International Pictures | true | false |
| 2 | 1 | The Chronicles of Narnia: Prince Caspian | $356,701 | -33.9% | 67 | -4 | $5,323 | $1,204,674 | 2 | Walt Disney Pictures | false | false |
| 3 | 3 | Speed Racer | $93,593 | -33.3% | 37 | -3 | $2,529 | $521,523 | 3 | Warner Bros. | false | false |
| 4 | 2 | Iron Man | $84,667 | -40.1% | 39 | +1 | $2,170 | $1,275,960 | 4 | United International Pictures | false | false |
| 5 | 4 | The Orphanage | $71,901 | -8.1% | 16 | - | $4,493 | $440,602 | 4 | CDI Films | false | false |
| 6 | 5 | Charlie Wilson's War | $28,069 | -30.7% | 8 | -12 | $3,508 | $163,555 | 3 | United International Pictures | false | false |
| 7 | 6 | An American Haunting | $28,052 | -19.9% | 11 | -4 | $2,550 | $363,962 | 6 | Bazuca Films | false | false |
| 8 | 7 | Elizabeth: The Golden Age | $13,361 | -23.7% | 4 | - | $3,340 | $39,260 | 2 | United International Pictures | false | false |
| 9 | 9 | Eastern Promises | $6,496 | -51.8% | 4 | -6 | $1,624 | $241,716 | 7 | Bazuca Films | false | false |
| 10 | 18 | Meet the Spartans | $5,498 | -4.1% | 6 | -1 | $916 | $146,093 | 5 | 20th Century Fox International | false | false |
| 11 | 13 | U2 3D | $5,232 | -28% | 1 | - | $5,232 | $39,171 | 4 | N/A | false | false |
| 12 | 11 | 31 Minutos: La Película | $5,195 | -39.9% | 8 | -4 | $649 | $1,103,317 | 9 | MC Film | false | false |
| 13 | 16 | The Page Turner | $4,389 | -29.7% | 2 | - | $2,194 | $20,177 | 3 | Four Films | false | false |
| 14 | 14 | Vantage Point | $3,886 | -45% | 2 | -2 | $1,943 | $273,843 | 7 | Sony Pictures Releasing | false | false |
| 15 | 10 | Shutter | $3,228 | -67.3% | 3 | -4 | $1,076 | $204,551 | 6 | 20th Century Fox International | false | false |
| 16 | 21 | After the Wedding | $2,237 | +46.5% | 2 | +1 | $1,118 | $69,637 | 9 | Transeuropa | false | false |
| 17 | 8 | Bordertown | $2,203 | -85% | 4 | -8 | $550 | $25,065 | 2 | Bazuca Films | false | false |
| 18 | 12 | Lokas | $1,143 | -86.3% | 1 | -6 | $1,143 | $641,538 | 8 | Andes Films | false | false |
| 19 | 27 | The Game Plan | $523 | +16.7% | 1 | -1 | $523 | $987,894 | 19 | Walt Disney Pictures | false | false |
| 20 | 17 | Horton Hears a Who! | $483 | -91.8% | 2 | -7 | $241 | $612,299 | 11 | 20th Century Fox International | false | false |
| 21 | 20 | The Eye | $370 | -84% | 1 | -2 | $370 | $103,661 | 7 | United International Pictures | false | false |
| 22 | 25 | Whisper | $338 | -33.5% | 1 | - | $338 | $21,636 | 5 | Transeuropa | false | false |
| 23 | 22 | Mansacue | $238 | -82% | 2 | -2 | $119 | $43,800 | 5 | N/A | false | false |
