| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Indiana Jones and the Kingdom of the Crystal Skull | $296,499 | -38.7% | 40 | - | $7,412 | $872,758 | 2 | United International Pictures | false | false |
| 2 | 2 | The Chronicles of Narnia: Prince Caspian | $287,058 | -19.5% | 38 | -29 | $7,554 | $1,545,482 | 3 | Walt Disney Pictures | false | false |
| 3 | - | What Happens in Vegas | $100,664 | - | 25 | - | $4,026 | $100,664 | 1 | 20th Century Fox International | true | false |
| 4 | 3 | Speed Racer | $71,466 | -23.6% | 31 | -6 | $2,305 | $603,380 | 4 | Warner Bros. | false | false |
| 5 | 5 | The Orphanage | $56,733 | -21.1% | 15 | -1 | $3,782 | $515,162 | 5 | CDI Films | false | false |
| 6 | 4 | Iron Man | $49,205 | -41.9% | 33 | -6 | $1,491 | $1,343,759 | 5 | United International Pictures | false | false |
| 7 | 7 | An American Haunting | $27,673 | -1.4% | 12 | +1 | $2,306 | $398,025 | 7 | Bazuca Films | false | false |
| 8 | - | Two Days in Paris | $27,076 | - | 6 | - | $4,512 | $27,076 | 1 | Impacto Cine | true | false |
| 9 | - | P2 | $18,256 | - | 12 | - | $1,521 | $18,256 | 1 | Bazuca Films | true | false |
| 10 | 6 | Charlie Wilson's War | $11,823 | -57.9% | 6 | -2 | $1,970 | $179,420 | 4 | United International Pictures | false | false |
| 11 | 12 | 31 Minutos: La Película | $4,107 | -20.9% | 7 | -1 | $586 | $1,107,842 | 10 | MC Film | false | false |
| 12 | 11 | U2 3D | $3,527 | -32.6% | 1 | - | $3,527 | $43,702 | 5 | N/A | false | false |
| 13 | 9 | Eastern Promises | $3,404 | -47.6% | 4 | - | $851 | $246,617 | 8 | Bazuca Films | false | false |
| 14 | 8 | Elizabeth: The Golden Age | $2,906 | -78.3% | 3 | -1 | $968 | $45,037 | 3 | United International Pictures | false | false |
| 15 | 10 | Meet the Spartans | $2,856 | -48.1% | 5 | -1 | $571 | $150,397 | 6 | 20th Century Fox International | false | false |
| 16 | 19 | The Game Plan | $316 | -39.6% | 2 | +1 | $158 | $988,214 | 20 | Walt Disney Pictures | false | false |
| 17 | 17 | Bordertown | $121 | -94.5% | 2 | -2 | $60 | $25,693 | 3 | Bazuca Films | false | false |
| 18 | 21 | The Eye | $30 | -91.9% | 1 | - | $30 | $103,925 | 8 | United International Pictures | false | false |
