| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Indiana Jones and the Kingdom of the Crystal Skull | $36,125 | -59.2% | 5 | - | $7,225 | $162,348 | 2 | Universal Pictures International (UPI) | false | false |
| 2 | 2 | What Happens in Vegas | $13,587 | -34.9% | 3 | - | $4,529 | $181,657 | 4 | Universal Pictures International (UPI) | false | false |
| 3 | - | Prom Night | $9,109 | - | 1 | - | $9,109 | $9,109 | 1 | Universal Pictures International (UPI) | true | false |
| 4 | - | Never Back Down | $4,885 | - | 1 | - | $4,885 | $4,885 | 1 | ACME | true | false |
| 5 | 3 | 21 | $4,880 | -8.3% | 3 | - | $1,626 | $184,745 | 7 | Universal Pictures International (UPI) | false | false |
| 6 | 4 | Iron Man | $2,931 | -31.6% | 3 | - | $977 | $110,312 | 5 | Universal Pictures International (UPI) | false | false |
| 7 | 9 | Leatherheads | $2,787 | +10.6% | 1 | - | $2,787 | $53,731 | 6 | Universal Pictures International (UPI) | false | false |
| 8 | 5 | Fool's Gold | $2,740 | -27.2% | 2 | - | $1,370 | $128,330 | 8 | Universal Pictures International (UPI) | false | false |
| 9 | 7 | Deception | $2,377 | -6.6% | 1 | - | $2,377 | $29,422 | 5 | ACME | false | false |
| 10 | 6 | The Orphanage | $2,198 | -27.7% | 1 | - | $2,198 | $37,268 | 6 | ACME | false | false |
| 11 | 8 | Female Agents | $1,599 | -36.8% | 1 | - | $1,599 | $17,519 | 4 | ACME | false | false |
| 12 | 10 | Speed Racer | $1,010 | -59.2% | 3 | - | $336 | $14,145 | 3 | Universal Pictures International (UPI) | false | false |
| 13 | 11 | Balls of Fury | $809 | -66.8% | 1 | - | $809 | $13,908 | 3 | Garsu Pasaulio Irasai | false | false |
| 14 | 12 | Horton Hears a Who! | $702 | -40.8% | 7 | - | $100 | $224,772 | 11 | Universal Pictures International (UPI) | false | false |
