| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 2 | The Chronicles of Narnia: Prince Caspian | $209,544 | -27% | 64 | +26 | $3,274 | $1,742,330 | 4 | Walt Disney Pictures | false | false |
| 2 | 1 | Indiana Jones and the Kingdom of the Crystal Skull | $181,582 | -38.8% | 70 | +30 | $2,594 | $1,121,630 | 3 | United International Pictures | false | false |
| 3 | 3 | What Happens in Vegas | $92,093 | -8.5% | 25 | - | $3,683 | $225,654 | 2 | 20th Century Fox International | false | false |
| 4 | - | 21 | $62,900 | - | 16 | - | $3,931 | $62,900 | 1 | Sony Pictures Releasing | true | false |
| 5 | 4 | Speed Racer | $50,820 | -28.9% | 30 | -1 | $1,694 | $629,392 | 5 | Warner Bros. | false | false |
| 6 | 5 | The Orphanage | $50,312 | -11.3% | 16 | +1 | $3,144 | $563,516 | 6 | CDI Films | false | false |
| 7 | - | Away from Her | $31,973 | - | 8 | - | $3,996 | $31,973 | 1 | Bazuca Films | true | false |
| 8 | 6 | Iron Man | $31,414 | -36.2% | 30 | -3 | $1,047 | $1,314,722 | 6 | United International Pictures | false | false |
| 9 | 7 | An American Haunting | $26,527 | -4.1% | 13 | +1 | $2,040 | $410,351 | 8 | Bazuca Films | false | false |
| 10 | - | The Ugly Duckling and Me! | $19,172 | - | 9 | - | $2,130 | $19,172 | 1 | Andes Films | true | false |
| 11 | 8 | Two Days in Paris | $17,772 | -34.4% | 6 | - | $2,962 | $43,147 | 2 | Impacto Cine | false | false |
| 12 | 9 | P2 | $11,456 | -37.2% | 10 | -2 | $1,145 | $36,616 | 2 | Bazuca Films | false | false |
| 13 | 10 | Charlie Wilson's War | $9,313 | -21.2% | 5 | -1 | $1,862 | $180,765 | 5 | United International Pictures | false | false |
| 14 | 13 | Eastern Promises | $3,731 | +9.6% | 5 | +1 | $746 | $239,316 | 9 | Bazuca Films | false | false |
| 15 | - | About Crying | $3,005 | - | 1 | - | $3,005 | $11,081 | 2 | Quality Films | false | false |
| 16 | 14 | Elizabeth: The Golden Age | $2,622 | -9.8% | 3 | - | $874 | $46,046 | 4 | United International Pictures | false | false |
| 17 | 12 | U2 3D | $2,578 | -26.9% | 1 | - | $2,578 | $46,583 | 6 | N/A | false | false |
| 18 | 11 | 31 Minutos: La Película | $2,101 | -48.8% | 6 | -1 | $350 | $1,060,529 | 11 | MC Film | false | false |
| 19 | - | The Page Turner | $1,528 | - | 1 | - | $1,528 | $24,630 | 5 | Four Films | false | false |
| 20 | 15 | Meet the Spartans | $762 | -73.3% | 3 | -2 | $254 | $153,041 | 7 | 20th Century Fox International | false | false |
| 21 | - | Lassie | $577 | - | 1 | - | $577 | $40,569 | 6 | Bazuca Films | false | false |
| 22 | - | Whisper | $501 | - | 2 | - | $250 | $21,877 | 7 | Transeuropa | false | false |
| 23 | 18 | The Eye | $405 | +1,250% | 2 | +1 | $202 | $99,803 | 9 | United International Pictures | false | false |
| 24 | 16 | The Game Plan | $100 | -68.4% | 1 | -1 | $100 | $943,428 | 21 | Walt Disney Pictures | false | false |
