| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | You Don't Mess with the Zohan | $2,007,900 | - | 400 | - | $5,019 | $2,007,900 | 1 | Sony Pictures Releasing | true | false |
| 2 | 3 | The Chronicles of Narnia: Prince Caspian | $1,300,781 | -36% | 720 | -119 | $1,806 | $16,902,055 | 4 | Walt Disney Pictures | false | false |
| 3 | 2 | What Happens in Vegas | $1,273,431 | -37.5% | 474 | +48 | $2,686 | $4,619,736 | 2 | 20th Century Fox International | false | false |
| 4 | 1 | Indiana Jones and the Kingdom of the Crystal Skull | $1,199,338 | -42.2% | 413 | -437 | $2,903 | $10,038,234 | 3 | Paramount Pictures International | false | false |
| 5 | - | Sex and the City | $1,198,351 | - | 420 | - | $2,853 | $1,198,351 | 1 | Gussi Films | true | false |
| 6 | 4 | Superhero Movie | $505,438 | -35.1% | 295 | -3 | $1,713 | $1,702,812 | 2 | Gussi Films | false | false |
| 7 | 6 | Speed Racer | $170,846 | -45.9% | 188 | -109 | $908 | $5,641,608 | 5 | Warner Bros. | false | false |
| 8 | 5 | Iron Man | $120,464 | -66% | 319 | -34 | $377 | $20,839,093 | 6 | Paramount Pictures International | false | false |
| 9 | 10 | Awake | $118,972 | +11.7% | 106 | +11 | $1,122 | $1,631,845 | 7 | Videocine | false | false |
| 10 | 8 | Déficit | $89,830 | -34.3% | 60 | - | $1,497 | $331,764 | 2 | Videocine | false | false |
| 11 | 7 | Made of Honor | $55,909 | -65.5% | 65 | -96 | $860 | $5,702,016 | 6 | Sony Pictures Releasing | false | false |
| 12 | 17 | Ladrón que roba a ladrón | $41,791 | +152.8% | 33 | +14 | $1,266 | $1,692,366 | 8 | Warner Bros. | false | false |
| 13 | 9 | 88 Minutes | $39,692 | -66.3% | 38 | -43 | $1,044 | $2,179,587 | 5 | Gussi Films | false | false |
| 14 | 11 | Bella | $31,487 | +11.5% | 73 | +19 | $431 | $652,612 | 6 | Videocine | false | false |
| 15 | 28 | The Nanny Diaries | $29,286 | +11,521.4% | 41 | +40 | $714 | $692,134 | 11 | Zima Entertainment | false | false |
| 16 | 12 | A Guide to Recognizing Your Saints | $25,105 | +6.8% | 48 | -11 | $523 | $200,215 | 3 | Videocine | false | false |
| 17 | - | Adrift in Manhattan | $19,055 | - | 23 | - | $828 | $19,055 | 1 | N/A | true | false |
| 18 | 14 | Chaos | $18,879 | +8.6% | 19 | -1 | $993 | $245,998 | 8 | Azteca Films | false | false |
| 19 | - | Irina Palm | $17,949 | - | 10 | - | $1,794 | $58,000 | 2 | Zima Entertainment | false | false |
| 20 | - | Priceless | $17,917 | - | 16 | - | $1,119 | $192,814 | 7 | Quality Films | false | false |
| 21 | - | I Could Never Be Your Woman | $17,731 | - | 28 | - | $633 | $1,578,645 | 11 | Videocine | false | false |
| 22 | - | Delta Farce | $16,735 | - | 30 | - | $557 | $16,735 | 1 | Corazón Films | true | false |
| 23 | - | Elizabeth: The Golden Age | $16,416 | - | 23 | - | $713 | $714,035 | 14 | Universal Pictures International (UPI) | false | false |
| 24 | 13 | Shutter | $15,481 | -31.9% | 15 | -8 | $1,032 | $3,714,722 | 9 | 20th Century Fox International | false | false |
| 25 | - | The Counterfeiters | $15,421 | - | 19 | - | $811 | $578,607 | 12 | Zima Entertainment | false | false |
| 26 | - | Persepolis | $13,608 | - | 5 | - | $2,721 | $13,608 | 1 | Film House | true | false |
| 27 | - | Hasta la muerte | $11,568 | - | 29 | - | $398 | $61,451 | 4 | Azteca Films | false | false |
| 28 | 23 | Street Kings | $10,273 | +90.6% | 14 | +6 | $733 | $2,731,178 | 8 | 20th Century Fox International | false | false |
| 29 | - | The Victim | $9,806 | - | 15 | - | $653 | $343,064 | 10 | - | false | false |
| 30 | - | One Night with the King | $9,457 | - | 11 | - | $859 | $143,091 | 10 | Quality Films | false | false |
| 31 | - | El brindis | $7,086 | - | 31 | - | $228 | $130,542 | 7 | David Distribucion | false | false |
| 32 | 15 | Elite Squad | $7,008 | -59.5% | 14 | -5 | $500 | $36,578 | 2 | Universal Pictures International (UPI) | false | false |
| 33 | 19 | Definitely, Maybe | $6,998 | -46.5% | 11 | -17 | $636 | $925,223 | 8 | Universal Pictures International (UPI) | false | false |
| 34 | - | Frontier(s) | $6,612 | - | 12 | - | $551 | $149,905 | 5 | Zima Entertainment | false | false |
| 35 | - | My Blueberry Nights | $6,425 | - | 12 | - | $535 | $255,515 | 10 | Corazón Films | false | false |
| 36 | - | The Unseeable 2008 Re-release | $5,677 | - | 9 | - | $630 | $337,162 | 19 | Zima Entertainment | false | false |
| 37 | - | Ira & Abby | $4,981 | - | 11 | - | $452 | $106,003 | 5 | Corazón Films | false | false |
| 38 | - | Eastern Promises | $4,900 | - | 14 | - | $350 | $715,138 | 14 | Gussi Films | false | false |
| 39 | - | Cassandra's Dream | $4,234 | - | 6 | - | $705 | $284,023 | 13 | Quality Films | false | false |
| 40 | - | Paranoid Park | $4,213 | - | 8 | - | $526 | $84,708 | 9 | Alphaville | false | false |
| 41 | - | Away from Her | $4,021 | - | 7 | - | $574 | $182,545 | 10 | Film House | false | false |
| 42 | 20 | Death Proof | $4,008 | -42.3% | 3 | -3 | $1,336 | $47,470 | 3 | Zima Entertainment | false | false |
| 43 | 18 | Captivity | $3,934 | -74.4% | 7 | -13 | $562 | $457,085 | 10 | Gussi Films | false | false |
| 44 | - | Equinoccio y la pirámide mágica | $3,789 | - | 14 | - | $270 | $39,603 | 50 | David Distribucion | false | false |
| 45 | - | La Vie En Rose | $3,557 | - | 6 | - | $592 | $760,093 | 16 | Quality Films | false | false |
| 46 | - | Control | $2,870 | - | 1 | - | $2,870 | $77,451 | 10 | MV Films | false | false |
| 47 | - | The Valet | $2,598 | - | 5 | - | $519 | $12,459 | 9 | Quality Films | false | false |
| 48 | - | Sweeney Todd: The Demon Barber of Fleet Street | $2,576 | - | 1 | - | $2,576 | $2,442,047 | 18 | Warner Bros. | false | false |
| 49 | - | Las vidas de Celia | $2,515 | - | 8 | - | $314 | $23,662 | 6 | Alphaville | false | false |
| 50 | - | Cashback | $2,308 | - | 8 | - | $288 | $41,535 | 8 | Quality Films | false | false |
| 51 | - | Conversations with Other Women | $2,043 | - | 4 | - | $510 | $65,911 | 11 | Alphaville | false | false |
| 52 | - | Más que a nada en el mundo | $1,924 | - | 10 | - | $192 | $149,810 | 16 | DCN | false | false |
| 53 | - | The 11th Hour | $1,895 | - | 12 | - | $157 | $28,226 | 14 | Warner Bros. | false | false |
| 54 | 21 | Death Sentence | $1,894 | -69.7% | 4 | -5 | $473 | $505,410 | 7 | Gussi Films | false | false |
| 55 | - | Drillbit Taylor | $1,831 | - | 2 | - | $915 | $3,950,502 | 12 | Paramount Pictures International | false | false |
| 56 | - | El custodio 2007 Re-release | $1,665 | - | 6 | - | $277 | $35,601 | 19 | David Distribucion | false | false |
| 57 | - | Half Moon | $1,618 | - | 3 | - | $539 | $30,654 | 6 | Quality Films | false | false |
| 58 | - | Unrest | $1,490 | - | 2 | - | $745 | $418,929 | 11 | - | false | false |
| 59 | 25 | Casi divas | $1,393 | -44% | 3 | -5 | $464 | $3,698,890 | 9 | Sony Pictures Releasing | false | false |
| 60 | - | Raising Flagg 2008 Re-release | $1,384 | - | 6 | - | $230 | $19,019 | 7 | N/A | false | false |
| 61 | - | My Best Friend | $1,352 | - | 5 | - | $270 | $71,599 | 21 | Quality Films | false | false |
| 62 | - | Before the Devil Knows You're Dead | $1,294 | - | 3 | - | $431 | $716,607 | 11 | - | false | false |
| 63 | - | Factory Girl | $1,076 | - | 2 | - | $538 | $86,166 | 6 | Film House | false | false |
| 64 | - | The Eye | $1,002 | - | 2 | - | $501 | $1,975,381 | 16 | Paramount Pictures International | false | false |
| 65 | - | 4 Months, 3 Weeks and 2 Days | $813 | - | 1 | - | $813 | $95,108 | 8 | Zima Entertainment | false | false |
| 66 | - | Silent Light | $791 | - | 1 | - | $791 | $258,289 | 35 | - | false | false |
| 67 | 16 | Bordertown | $785 | -95.3% | 2 | -16 | $392 | $410,980 | 4 | Gussi Films | false | false |
| 68 | - | No Country for Old Men | $760 | - | 2 | - | $380 | $1,776,430 | 18 | Paramount Pictures International | false | false |
| 69 | - | December Boys | $755 | - | 2 | - | $377 | $240,207 | 32 | Warner Bros. | false | false |
| 70 | - | Lust, Caution | $726 | - | 1 | - | $726 | $213,286 | 11 | Gussi Films | false | false |
| 71 | - | Noticias de una guerra | $671 | - | 1 | - | $671 | $3,247 | 3 | N/A | false | false |
| 72 | - | Summer '04 | $659 | - | 3 | - | $219 | $21,693 | 5 | Cinemas Nueva Era | false | false |
| 73 | - | I'm Not There | $618 | - | 3 | - | $206 | $60,101 | 9 | Azteca Films | false | false |
| 74 | - | Berlin-Alexanderplatz: The Story of Franz Biberkopf | $616 | - | 1 | - | $616 | $1,056 | 1 | N/A | true | false |
| 75 | - | Curious George | $485 | - | 1 | - | $485 | $405,513 | 94 | N/A | false | false |
| 76 | 24 | Trade | $473 | -84.6% | 1 | -7 | $473 | $152,776 | 8 | Gussi Films | false | false |
| 77 | - | My Mexican Shivah | $461 | - | 2 | - | $230 | $653,511 | 33 | David Distribucion | false | false |
| 78 | - | Cobrador: In God We Trust | $434 | - | 2 | - | $217 | $114,771 | 20 | - | false | false |
| 79 | - | The Secret | $393 | - | 2 | - | $196 | $368,041 | 20 | Azteca Films | false | false |
| 80 | - | Things We Lost in the Fire | $370 | - | 1 | - | $370 | $748,251 | 24 | Paramount Pictures International | false | false |
| 81 | - | Under the Same Moon | $359 | - | 1 | - | $359 | $9,778,404 | 12 | 20th Century Fox International | false | false |
| 82 | - | Noah's Ark | $337 | - | 4 | - | $84 | $1,327,209 | 19 | Walt Disney Pictures | false | false |
| 83 | - | Used Parts | $317 | - | 2 | - | $158 | $61,906 | 8 | Canana Films | false | false |
| 84 | - | The Kite Runner | $310 | - | 3 | - | $103 | $330,319 | 22 | Paramount Pictures International | false | false |
| 85 | - | Trivial | $278 | - | 1 | - | $278 | $39,543 | 18 | - | false | false |
| 86 | - | The Favor | $236 | - | 1 | - | $236 | $46,617 | 34 | Azteca Films | false | false |
| 87 | - | The Spiderwick Chronicles | $179 | - | 1 | - | $179 | $6,582,946 | 14 | Paramount Pictures International | false | false |
| 88 | - | Bear Cub 2008 Re-release | $122 | - | 1 | - | $122 | $37,322 | 19 | Alphaville | false | false |
| 89 | - | Sharks 3D | $117 | - | 1 | - | $117 | $47,469 | 124 | Distribution Company | false | false |
| 90 | - | One Missed Call | $116 | - | 2 | - | $58 | $3,419,857 | 12 | Warner Bros. | false | false |
| 91 | - | There Will Be Blood | $115 | - | 1 | - | $115 | $624,015 | 16 | Walt Disney Pictures | false | false |
| 92 | - | Black Christmas | $100 | - | 1 | - | $100 | $489,328 | 25 | Gussi Films | false | false |
| 93 | - | The Zone | $90 | - | 1 | - | $90 | $716,447 | 13 | Gussi Films | false | false |
| 94 | - | Fragile | $84 | - | 1 | - | $84 | $1,285,184 | 16 | Videocine | false | false |
| 95 | - | Old Thieves: The Legend of Artegio | $78 | - | 3 | - | $26 | $47,533 | 17 | Film House | false | false |
| 96 | - | Happy Feet | $20 | - | 1 | - | $20 | $6,252,783 | 79 | Warner Bros. | false | false |
