| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Happening | $223,054 | - | 45 | - | $4,956 | $223,054 | 1 | 20th Century Fox International | true | false |
| 2 | 1 | The Chronicles of Narnia: Prince Caspian | $129,364 | -38.3% | 53 | -11 | $2,440 | $1,919,839 | 5 | Walt Disney Pictures | false | false |
| 3 | - | The Incredible Hulk | $125,119 | - | 56 | - | $2,234 | $125,119 | 1 | United International Pictures | true | false |
| 4 | 2 | Indiana Jones and the Kingdom of the Crystal Skull | $80,361 | -55.7% | 51 | -19 | $1,575 | $1,237,260 | 4 | United International Pictures | false | false |
| 5 | 3 | What Happens in Vegas | $44,206 | -52% | 24 | -1 | $1,841 | $291,953 | 3 | 20th Century Fox International | false | false |
| 6 | 4 | 21 | $31,244 | -50.3% | 20 | +4 | $1,562 | $113,864 | 2 | Sony Pictures Releasing | false | false |
| 7 | 6 | The Orphanage | $25,938 | -48.4% | 15 | -1 | $1,729 | $604,773 | 7 | CDI Films | false | false |
| 8 | 7 | Away from Her | $22,054 | -31% | 7 | -1 | $3,150 | $63,612 | 2 | Bazuca Films | false | false |
| 9 | 5 | Speed Racer | $18,032 | -64.5% | 20 | -10 | $901 | $654,379 | 6 | Warner Bros. | false | false |
| 10 | 10 | The Ugly Duckling and Me! | $14,205 | -25.9% | 10 | +1 | $1,420 | $36,059 | 2 | Andes Films | false | false |
| 11 | 9 | An American Haunting | $10,899 | -58.9% | 7 | -6 | $1,557 | $428,545 | 9 | Bazuca Films | false | false |
| 12 | 11 | Two Days in Paris | $9,948 | -44% | 5 | -1 | $1,989 | $57,442 | 3 | Impacto Cine | false | false |
| 13 | 8 | Iron Man | $3,107 | -90.1% | 9 | -21 | $345 | $1,383,728 | 7 | United International Pictures | false | false |
| 14 | 14 | Eastern Promises | $1,755 | -53% | 1 | -4 | $1,755 | $241,072 | 10 | Bazuca Films | false | false |
| 15 | 13 | Charlie Wilson's War | $1,735 | -81.4% | 3 | -2 | $578 | $191,422 | 6 | United International Pictures | false | false |
| 16 | 15 | About Crying | $754 | -74.9% | 1 | - | $754 | $13,403 | 3 | Quality Films | false | false |
| 17 | 12 | P2 | $310 | -97.3% | 2 | -8 | $155 | $40,633 | 3 | Bazuca Films | false | false |
| 18 | 18 | 31 Minutos: La Película | $243 | -88.4% | 2 | -4 | $121 | $1,060,772 | 12 | MC Film | false | false |
| 19 | 23 | The Eye | $130 | -67.9% | 1 | -1 | $130 | $100,233 | 10 | United International Pictures | false | false |
| 20 | - | Shutter | $110 | - | 1 | - | $110 | $190,955 | 9 | 20th Century Fox International | false | false |
