| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Sex and the City | $807,134 | - | 108 | - | $7,473 | $1,223,467 | 1 | Paradiso Entertainment | true | false |
| 2 | 1 | Indiana Jones and the Kingdom of the Crystal Skull | $522,329 | -17.9% | 127 | -5 | $4,112 | $4,674,121 | 4 | Universal Pictures International (UPI) | false | false |
| 3 | - | The Happening | $407,588 | - | 78 | - | $5,225 | $407,588 | 1 | Warner Bros. | true | false |
| 4 | 2 | What Happens in Vegas | $195,418 | -34.7% | 93 | - | $2,101 | $3,310,918 | 6 | Warner Bros. | false | false |
| 5 | 3 | Made of Honor | $124,110 | -36.2% | 60 | - | $2,068 | $414,053 | 2 | Sony Pictures Releasing | false | false |
| 6 | 6 | I've Loved You So Long | $59,141 | +3.8% | 22 | - | $2,688 | $159,994 | 2 | Benelux Film Distributors | false | false |
| 7 | 4 | Taken | $47,334 | -25.2% | 30 | -5 | $1,577 | $866,036 | 7 | Independent Films | false | false |
| 8 | 14 | Morrison krijgt een zusje | $45,738 | +153.3% | 85 | - | $538 | $598,831 | 8 | Warner Bros. | false | false |
| 9 | 8 | Into the Wild | $44,623 | +1.5% | 23 | - | $1,940 | $790,500 | 8 | A-Film Distribution | false | false |
| 10 | 16 | Horton Hears a Who! | $37,545 | +186.4% | 62 | -6 | $605 | $1,966,740 | 13 | Warner Bros. | false | false |
| 11 | 5 | Iron Man | $36,836 | -40.6% | 28 | -47 | $1,315 | $1,992,726 | 7 | Universal Pictures International (UPI) | false | false |
| 12 | 7 | Dunya & Desie | $33,083 | -37.5% | 65 | -12 | $508 | $2,068,046 | 9 | Independent Films | false | false |
| 13 | 10 | Happy-Go-Lucky | $24,603 | -13.9% | 20 | -1 | $1,230 | $290,045 | 5 | RCV Film Distribution | false | false |
| 14 | 15 | Winx Club: The Secret of the Lost Kingdom | $23,592 | +65.6% | 87 | -11 | $271 | $663,590 | 9 | Independent Films | false | false |
| 15 | 19 | Dragon Hunters | $19,725 | +91.3% | 50 | -4 | $394 | $240,098 | 8 | Independent Films | false | false |
| 16 | 9 | Over Her Dead Body | $14,222 | -61% | 14 | -6 | $1,015 | $274,559 | 4 | RCV Film Distribution | false | false |
| 17 | - | Alvin and the Chipmunks | $14,050 | - | 16 | - | $878 | $4,229,705 | 19 | 20th Century Fox International | false | false |
| 18 | 11 | How She Move | $12,249 | -53.8% | 5 | - | $2,449 | $62,823 | 2 | Universal Pictures International (UPI) | false | false |
| 19 | 13 | All the Boys Love Mandy Lane | $10,391 | -53.5% | 13 | -2 | $799 | $131,538 | 3 | Moonlight Films | false | false |
| 20 | 18 | Be Kind Rewind | $8,106 | -24.2% | 12 | -1 | $675 | $188,848 | 5 | A-Film Distribution | false | false |
| 21 | - | Free Rainer | $2,745 | - | 7 | - | $392 | $2,745 | 1 | Cinemien | true | false |
| 22 | - | Closing the Ring | $966 | - | 3 | - | $322 | $966 | 1 | A-Film Distribution | true | false |
