| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | WALL·E | $545,035 | - | 57 | - | $9,562 | $545,035 | 1 | Walt Disney Pictures | true | false |
| 2 | 1 | Get Smart | $136,284 | -29.2% | 49 | +1 | $2,781 | $366,071 | 2 | Warner Bros. | false | false |
| 3 | 2 | The Happening | $122,610 | -28.6% | 40 | -3 | $3,065 | $643,871 | 3 | 20th Century Fox International | false | false |
| 4 | 3 | The Chronicles of Narnia: Prince Caspian | $66,360 | -38.3% | 35 | -7 | $1,896 | $2,148,304 | 7 | Walt Disney Pictures | false | false |
| 5 | 4 | The Incredible Hulk | $39,372 | -51.4% | 32 | -13 | $1,230 | $312,808 | 3 | United International Pictures | false | false |
| 6 | 5 | Indiana Jones and the Kingdom of the Crystal Skull | $23,568 | -51.8% | 14 | -20 | $1,683 | $1,336,530 | 6 | United International Pictures | false | false |
| 7 | 7 | 21 | $23,365 | +2.5% | 11 | -3 | $2,124 | $175,217 | 4 | Sony Pictures Releasing | false | false |
| 8 | - | Definitely, Maybe | $22,102 | - | 15 | - | $1,473 | $22,102 | 1 | United International Pictures | true | false |
| 9 | - | Street Kings | $18,876 | - | 8 | - | $2,359 | $19,127 | 1 | 20th Century Fox International | true | false |
| 10 | 6 | What Happens in Vegas | $14,240 | -52.5% | 10 | -7 | $1,424 | $356,854 | 5 | 20th Century Fox International | false | false |
| 11 | 9 | Away from Her | $11,097 | -38.7% | 4 | -2 | $2,774 | $103,201 | 4 | Bazuca Films | false | false |
| 12 | 8 | The Orphanage | $9,540 | -54.2% | 10 | -6 | $954 | $651,821 | 9 | CDI Films | false | false |
| 13 | - | Elite Squad | $7,204 | - | 6 | - | $1,200 | $7,204 | 1 | United International Pictures | true | false |
| 14 | - | Shine a Light | $6,850 | - | 10 | - | $685 | $6,850 | 1 | N/A | true | false |
| 15 | 13 | An American Haunting | $3,162 | -55.5% | 1 | -5 | $3,162 | $446,065 | 11 | Bazuca Films | false | false |
| 16 | 11 | The Ugly Duckling and Me! | $2,249 | -85% | 5 | -3 | $449 | $58,267 | 4 | Andes Films | false | false |
| 17 | 14 | Two Days in Paris | $2,117 | -60.2% | 1 | -2 | $2,117 | $90,695 | 5 | Impacto Cine | false | false |
| 18 | 15 | Speed Racer | $1,506 | -70.5% | 3 | -1 | $502 | $664,921 | 8 | Warner Bros. | false | false |
| 19 | 10 | The Hunting Party | $620 | -95.9% | 3 | -12 | $206 | $18,793 | 2 | Bazuca Films | false | false |
| 20 | 12 | The Nanny Diaries | $339 | -96.7% | 2 | -6 | $169 | $13,076 | 2 | Transeuropa | false | false |
| 21 | - | Shutter | $121 | - | 1 | - | $121 | $209,914 | 11 | 20th Century Fox International | false | false |
