| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Kung Fu Panda | $537,602 | - | 106 | - | $5,071 | $537,602 | 1 | United International Pictures | true | false |
| 2 | - | Harold & Kumar Escape from Guantanamo Bay | $93,489 | - | 30 | - | $3,116 | $93,489 | 1 | NuMetro Distribution | true | false |
| 3 | 1 | The Incredible Hulk | $93,377 | -33.9% | 71 | +1 | $1,315 | $674,421 | 3 | United International Pictures | false | false |
| 4 | 2 | College Road Trip | $92,876 | -15.1% | 40 | - | $2,321 | $271,235 | 2 | Ster-Kinekor Pictures | false | false |
| 5 | 3 | The Chronicles of Narnia: Prince Caspian | $67,929 | -28.8% | 77 | -10 | $882 | $846,226 | 4 | Ster-Kinekor Pictures | false | false |
| 6 | 6 | What Happens in Vegas | $58,004 | -1.3% | 53 | -2 | $1,094 | $1,245,006 | 7 | NuMetro Distribution | false | false |
| 7 | 4 | Forgetting Sarah Marshall | $54,146 | -33.1% | 50 | +1 | $1,082 | $181,507 | 2 | United International Pictures | false | false |
| 8 | 7 | Sex and the City | $46,152 | -20.3% | 44 | -3 | $1,048 | $794,995 | 5 | NuMetro Distribution | false | false |
| 9 | 5 | The Happening | $44,199 | -28.4% | 50 | -10 | $883 | $317,931 | 3 | NuMetro Distribution | false | false |
| 10 | 9 | Indiana Jones and the Kingdom of the Crystal Skull | $26,124 | -19.9% | 31 | -13 | $842 | $1,087,653 | 6 | United International Pictures | false | false |
| 11 | 10 | Definitely, Maybe | $25,088 | -22.7% | 28 | -4 | $896 | $313,731 | 4 | United International Pictures | false | false |
| 12 | 8 | Speed Racer | $22,124 | -40.5% | 62 | - | $356 | $83,868 | 2 | NuMetro Distribution | false | false |
| 13 | - | Thoda Pyaar Thoda Magic | $22,090 | - | 8 | - | $2,761 | $22,090 | 1 | NuMetro Distribution | true | false |
| 14 | 14 | Iron Man | $11,010 | +18.8% | 15 | -3 | $734 | $1,387,598 | 9 | United International Pictures | false | false |
| 15 | 13 | Married Life | $8,422 | -23.1% | 8 | -2 | $1,052 | $44,345 | 3 | NuMetro Distribution | false | false |
| 16 | 11 | Mama's Boy | $7,221 | -64.5% | 15 | -14 | $481 | $108,206 | 3 | Ster-Kinekor Pictures | false | false |
| 17 | - | Goya's Ghosts | $6,944 | - | 5 | - | $1,388 | $6,944 | 1 | Ster-Kinekor Pictures | true | false |
| 18 | 15 | Made of Honor | $4,361 | -16% | 6 | -8 | $726 | $792,939 | 9 | United International Pictures | false | false |
| 19 | 12 | Never Back Down | $4,139 | -73.5% | 12 | -19 | $344 | $64,872 | 3 | NuMetro Distribution | false | false |
| 20 | 20 | Rogue | $3,414 | +28.3% | 6 | +1 | $569 | $71,165 | 5 | Ster-Kinekor Pictures | false | false |
| 21 | 19 | Brick Lane | $3,108 | -21.2% | 6 | - | $518 | $50,725 | 7 | Ster-Kinekor Pictures | false | false |
| 22 | 22 | First Sunday | $2,045 | +34.9% | 3 | - | $681 | $168,942 | 10 | United International Pictures | false | false |
