| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Hancock | $1,321,557 | +11.1% | 123 | +30 | $10,744 | $3,019,391 | 2 | Walt Disney Pictures | false | false |
| 2 | 2 | Kung Fu Panda | $938,995 | +56% | 103 | +29 | $9,116 | $1,969,594 | 2 | Universal Pictures International (UPI) | false | false |
| 3 | 6 | Welcome to the Sticks | $227,368 | +64.3% | 17 | -1 | $13,374 | $5,669,243 | 20 | Pathé | false | false |
| 4 | 4 | Indiana Jones and the Kingdom of the Crystal Skull | $147,063 | +1% | 35 | -6 | $4,201 | $5,626,527 | 8 | Universal Pictures International (UPI) | false | false |
| 5 | 3 | The Chronicles of Narnia: Prince Caspian | $129,294 | -42.3% | 31 | - | $4,170 | $673,130 | 3 | Walt Disney Pictures | false | false |
| 6 | 5 | Sex and the City | $128,818 | -7.2% | 37 | -5 | $3,481 | $3,478,111 | 7 | Warner Bros. | false | false |
| 7 | - | Nim's Island | $110,438 | - | 27 | - | $4,090 | $397,111 | 14 | Ascot Elite Entertainment Group | false | false |
| 8 | 8 | 21 | $92,822 | +20.5% | 15 | -107 | $6,188 | $816,238 | 6 | Walt Disney Pictures | false | false |
| 9 | 11 | Forgetting Sarah Marshall | $59,478 | +15.5% | 17 | -3 | $3,498 | $418,674 | 5 | Universal Pictures International (UPI) | false | false |
| 10 | 7 | The Incredible Hulk | $45,598 | -57.6% | 24 | -2 | $1,899 | $222,261 | 4 | Universal Pictures International (UPI) | false | false |
| 11 | - | Miss Pettigrew Lives for a Day | $41,339 | - | 6 | - | $6,889 | $41,339 | 1 | Ascot Elite Entertainment Group | true | false |
| 12 | 14 | What Happens in Vegas | $37,769 | +36.1% | 9 | -1 | $4,196 | $2,250,590 | 10 | 20th Century Fox International | false | false |
| 13 | 10 | Made of Honor | $32,211 | -41.7% | 10 | -6 | $3,221 | $946,218 | 9 | Walt Disney Pictures | false | false |
| 14 | 20 | I Always Wanted to Be a Gangster | $29,202 | +115.7% | 4 | - | $7,300 | $150,920 | 13 | Frenetic Films | false | false |
| 15 | 9 | The Happening | $27,183 | -54.5% | 13 | -14 | $2,091 | $577,063 | 5 | 20th Century Fox International | false | false |
| 16 | 15 | Waltz with Bashir | $25,360 | +13.8% | 6 | +1 | $4,226 | $75,704 | 3 | Frenetic Films | false | false |
| 17 | - | Married Life | $22,750 | - | 4 | - | $5,687 | $22,750 | 1 | Rialto Distribution | true | false |
| 18 | 17 | The Wave | $21,309 | +31.9% | 8 | -2 | $2,663 | $907,999 | 11 | Rialto Distribution | false | false |
| 19 | - | Hotel Very Welcome | $17,798 | - | 4 | - | $4,449 | $38,774 | 2 | Rialto Distribution | false | false |
| 20 | 19 | The Game Plan | $16,610 | +5.5% | 15 | -3 | $1,107 | $413,001 | 11 | Walt Disney Pictures | false | false |
| 21 | 18 | The Nanny Diaries | $11,265 | -30% | 7 | -1 | $1,609 | $111,926 | 5 | Ascot Elite Entertainment Group | false | false |
