| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | WALL·E | $96,998 | - | 10 | - | $9,699 | $96,998 | 1 | Universal Pictures International (UPI) | true | false |
| 2 | - | You Don't Mess with the Zohan | $48,811 | - | 6 | - | $8,135 | $48,811 | 1 | ACME | true | false |
| 3 | - | Mamma Mia! | $40,616 | - | 7 | - | $5,802 | $47,321 | 1 | Universal Pictures International (UPI) | true | false |
| 4 | - | Hancock | $25,050 | -32.2% | 8 | - | $3,131 | $292,025 | 3 | ACME | false | false |
| 5 | - | Wanted | $14,795 | -17.1% | 6 | - | $2,465 | $248,195 | 4 | Universal Pictures International (UPI) | false | false |
| 6 | - | Kung Fu Panda | $9,058 | -38% | 9 | - | $1,006 | $493,539 | 7 | Universal Pictures International (UPI) | false | false |
| 7 | - | Virgin Territory | $5,160 | -34.6% | 4 | - | $1,290 | $24,060 | 2 | ACME | false | false |
| 8 | - | The Forbidden Kingdom | $3,808 | -61.3% | 4 | - | $952 | $28,118 | 2 | MEED Films | false | false |
| 9 | - | The Chronicles of Narnia: Prince Caspian | $2,410 | -57.7% | 3 | -3 | $803 | $142,719 | 5 | Universal Pictures International (UPI) | false | false |
| 10 | - | Sex and the City | $2,182 | -51.1% | 4 | -2 | $545 | $282,004 | 7 | Garsu Pasaulio Irasai | false | false |
| 11 | - | Deception | $1,591 | -61% | 3 | - | $530 | $12,063 | 2 | ACME | false | false |
| 12 | - | Forgetting Sarah Marshall | $1,014 | -62% | 4 | -2 | $253 | $107,255 | 5 | Universal Pictures International (UPI) | false | false |
| 13 | - | Funny Games | $972 | -71.8% | 3 | - | $324 | $10,478 | 2 | ACME | false | false |
| 14 | - | Pathology | $893 | -65.3% | 2 | -2 | $446 | $26,391 | 3 | ACME | false | false |
| 15 | - | The Orphanage | $531 | -54.5% | 1 | -2 | $531 | $38,707 | 5 | ACME | false | false |
| 16 | - | Indiana Jones and the Kingdom of the Crystal Skull | $403 | -33.8% | 2 | - | $201 | $268,336 | 9 | Universal Pictures International (UPI) | false | false |
| 17 | - | Lost in Beijing | $382 | +3.2% | 1 | - | $382 | $7,925 | 4 | N/A | false | false |
| 18 | - | Never Back Down | $320 | +119.2% | 3 | - | $106 | $14,087 | 4 | ACME | false | false |
| 19 | - | The Incredible Hulk | $199 | -70.9% | 2 | - | $99 | $52,214 | 6 | Universal Pictures International (UPI) | false | false |
| 20 | - | Horton Hears a Who! | $164 | - | 1 | - | $164 | $405,213 | 18 | Universal Pictures International (UPI) | false | false |
