| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | A Boyfriend for My Wife | $290,682 | -19.4% | 76 | +4 | $3,824 | $5,143,716 | 7 | Walt Disney Pictures | false | false |
| 2 | 2 | You Don't Mess with the Zohan | $124,241 | -36.4% | 30 | - | $4,141 | $360,110 | 2 | Sony Pictures Releasing | false | false |
| 3 | 4 | Tropic Thunder | $115,674 | -21.3% | 48 | +1 | $2,409 | $1,052,462 | 4 | United International Pictures | false | false |
| 4 | 3 | Tinker Bell | $108,098 | -30.3% | 58 | +4 | $1,863 | $590,609 | 3 | Walt Disney Pictures | false | false |
| 5 | 6 | Mamma Mia! | $92,937 | -18.4% | 49 | -1 | $1,896 | $1,351,321 | 6 | United International Pictures | false | false |
| 6 | - | Dan in Real Life | $85,313 | - | 31 | - | $2,752 | $85,313 | 1 | Distribution Company | true | false |
| 7 | - | Eagle Eye | $82,109 | - | 40 | - | $2,052 | $82,109 | 1 | United International Pictures | true | false |
| 8 | 5 | Taken | $81,289 | -34% | 30 | - | $2,709 | $236,296 | 2 | 20th Century Fox International | false | false |
| 9 | 10 | The Strangers | $51,432 | -17.4% | 32 | +1 | $1,607 | $272,035 | 3 | Distribution Company | false | false |
| 10 | 8 | Reasons for Not Falling in Love | $46,271 | -43% | 44 | +1 | $1,051 | $525,804 | 4 | Distribution Company | false | false |
| 11 | 9 | My Brother is an Only Child | $45,998 | -27.7% | 13 | +1 | $3,538 | $125,796 | 2 | Alfa Films | false | false |
| 12 | 7 | Superhero Movie | $40,305 | -50.8% | 39 | -1 | $1,033 | $288,514 | 3 | Pachamama Cine | false | false |
| 13 | - | Manual of Love 2008 Re-release | $28,698 | - | 9 | - | $3,188 | $28,698 | 1 | Notro Films | true | false |
| 14 | 11 | REC | $25,945 | -45.5% | 20 | +1 | $1,297 | $166,926 | 3 | CDI Films | false | false |
| 15 | 14 | Babylon A.D. | $21,149 | -6.1% | 30 | - | $704 | $200,336 | 4 | 20th Century Fox International | false | false |
| 16 | - | Irina Palm | $20,131 | - | 11 | - | $1,830 | $20,131 | 1 | Alfa Films | true | false |
| 17 | 12 | Wanted | $19,626 | -44% | 46 | +2 | $426 | $552,699 | 5 | United International Pictures | false | false |
| 18 | 16 | La próxima estación | $16,505 | +7.1% | 12 | +5 | $1,375 | $90,008 | 4 | Primer Plano Film Group | false | false |
| 19 | 13 | Hannah Montana and Miley Cyrus: Best of Both Worlds Concert | $16,304 | -27.7% | 2 | - | $8,152 | $123,825 | 4 | Walt Disney Pictures | false | false |
| 20 | 15 | The Bottle | $13,784 | -18.9% | 18 | -6 | $765 | $80,326 | 3 | Primer Plano Film Group | false | false |
| 21 | 21 | Francesca | $8,276 | -10.5% | 6 | - | $1,379 | $170,771 | 11 | IFA | false | false |
| 22 | 23 | L'invité | $7,806 | -5% | 8 | -4 | $975 | $129,277 | 5 | Pachamama Cine | false | false |
| 23 | 20 | Run Fatboy Run | $5,644 | -39.3% | 12 | -4 | $470 | $78,196 | 5 | Distribution Company | false | false |
| 24 | 24 | Journey to the Center of the Earth | $5,248 | -20.8% | 10 | -3 | $524 | $933,648 | 11 | Distribution Company | false | false |
| 25 | 17 | Four Minutes | $5,038 | -65.4% | 9 | -5 | $559 | $161,383 | 5 | Alfa Films | false | false |
| 26 | 19 | The X Files: I Want to Believe | $4,128 | -59.6% | 31 | -10 | $133 | $700,837 | 7 | 20th Century Fox International | false | false |
| 27 | 22 | Black Sheep | $3,956 | -52% | 13 | -3 | $304 | $149,006 | 6 | Pachamama Cine | false | false |
| 28 | 25 | Meet Dave | $3,918 | -39.1% | 16 | -10 | $244 | $290,526 | 8 | 20th Century Fox International | false | false |
| 29 | 33 | Nim's Island | $3,722 | +82.7% | 17 | +5 | $218 | $157,037 | 8 | United International Pictures | false | false |
| 30 | 26 | Chaos | $3,368 | -45.2% | 16 | +1 | $210 | $95,058 | 7 | - | false | false |
| 31 | - | Aaltra | $2,913 | - | 2 | - | $1,456 | $2,913 | 1 | Vera Films | true | false |
| 32 | 29 | The Mummy: Tomb of the Dragon Emperor | $2,773 | -41.4% | 13 | -6 | $213 | $2,885,725 | 9 | United International Pictures | false | false |
| 33 | 18 | The Dark Knight | $2,742 | -73.5% | 9 | -9 | $304 | $5,476,600 | 11 | Warner Bros. | false | false |
| 34 | 40 | You, the Living | $2,480 | +108.6% | 7 | +4 | $354 | $20,489 | 4 | Zeta Films | false | false |
| 35 | 28 | Star Wars: The Clone Wars | $2,458 | -57.5% | 12 | -17 | $204 | $241,554 | 7 | Warner Bros. | false | false |
| 36 | 41 | Comedy of Innocence | $2,410 | +108.3% | 4 | +1 | $602 | $19,908 | 362 | Primer Plano Film Group | false | false |
| 37 | 27 | The Headless Woman | $1,955 | -67.3% | 7 | -7 | $279 | $135,336 | 6 | Distribution Company | false | false |
| 38 | 32 | Before the Devil Knows You're Dead | $1,903 | -32.9% | 3 | -13 | $634 | $595,095 | 12 | Distribution Company | false | false |
| 39 | 56 | The Other Boleyn Girl | $1,658 | +490% | 5 | +3 | $331 | $338,048 | 8 | Distribution Company | false | false |
| 40 | 31 | WALL·E | $1,353 | -60.3% | 12 | -4 | $112 | $4,819,697 | 12 | Walt Disney Pictures | false | false |
| 41 | - | Saint Ralph 2008 Re-release | $1,229 | - | 5 | - | $245 | $1,229 | 1 | Distribution Company | true | false |
| 42 | 30 | Golden Door | $1,156 | -75.2% | 1 | -2 | $1,156 | $7,327 | 2 | Primer Plano Film Group | false | false |
| 43 | 36 | The Diving Bell and the Butterfly | $1,155 | -23.1% | 3 | -1 | $385 | $105,289 | 7 | Alfa Films | false | false |
| 44 | 42 | Lars and the Real Girl | $676 | -39.8% | 6 | +2 | $112 | $76,541 | 6 | Impacto Cine | false | false |
| 45 | 50 | Hunting and Gathering | $617 | +8.1% | 4 | - | $154 | $22,344 | 5 | Notro Films | false | false |
| 46 | 49 | The Counterfeiters | $585 | -7.1% | 3 | +1 | $195 | $398,205 | 20 | Alfa Films | false | false |
| 47 | 45 | The Price to Pay | $579 | -30.1% | 4 | -1 | $144 | $131,936 | 9 | Impacto Cine | false | false |
| 48 | 46 | 100% lucha, la película | $516 | -37.3% | 5 | -4 | $103 | $949,611 | 12 | Primer Plano Film Group | false | false |
| 49 | 38 | Cassandra's Dream | $475 | -60.4% | 3 | - | $158 | $582,389 | 17 | Alfa Films | false | false |
| 50 | 37 | Los superagentes, nueva generación | $439 | -67.4% | 5 | -3 | $87 | $893,155 | 11 | Argentina Sono Film S.A.C.I. | false | false |
| 51 | 44 | A Secret | $382 | -57.8% | 1 | -2 | $382 | $207,016 | 15 | Alfa Films | false | false |
| 52 | 57 | Under the Same Moon | $371 | +51.4% | 4 | +2 | $92 | $27,572 | 6 | 20th Century Fox International | false | false |
| 53 | - | Café de los maestros | $357 | - | 1 | - | $357 | $102,636 | 14 | Alfa Films | false | false |
| 54 | 43 | Valentina: The Movie | $320 | -66.6% | 3 | -5 | $106 | $377,476 | 12 | Pachamama Cine | false | false |
| 55 | 48 | Kung Fu Panda | $299 | -60.4% | 3 | -1 | $99 | $5,798,938 | 13 | United International Pictures | false | false |
| 56 | 35 | A Girl Cut in Two | $288 | -82.2% | 2 | -2 | $144 | $294,588 | 10 | Alfa Films | false | false |
| 57 | 47 | A Guide to Recognizing Your Saints | $276 | -64.1% | 3 | - | $92 | $14,087 | 5 | CDI Films | false | false |
| 58 | 55 | Paranoid Park | $268 | -27.8% | 2 | - | $134 | $9,471 | 6 | Alfa Films | false | false |
| 59 | 60 | Conversations with My Gardener | $208 | +26.1% | 1 | - | $208 | $246,509 | 23 | Alfa Films | false | false |
| 60 | - | The Mist | $197 | - | 1 | - | $197 | $428,010 | 17 | Distribution Company | false | false |
| 61 | 39 | My Blueberry Nights | $188 | -84.2% | 1 | -4 | $188 | $226,167 | 14 | Distribution Company | false | false |
| 62 | 64 | The Chronicles of Narnia: Prince Caspian | $140 | +3.7% | 2 | +1 | $70 | $3,701,588 | 16 | Walt Disney Pictures | false | false |
| 63 | - | Made of Honor | $111 | - | 2 | - | $55 | $355,379 | 17 | Sony Pictures Releasing | false | false |
| 64 | 67 | Get Smart | $107 | +69.8% | 1 | - | $107 | $2,329,049 | 14 | Warner Bros. | false | false |
| 65 | 58 | Viva High School Musical | $59 | -73.2% | 1 | -2 | $59 | $1,827,051 | 11 | Walt Disney Pictures | false | false |
| 66 | 65 | Hancock | $58 | -54.3% | 1 | -1 | $58 | $2,309,663 | 13 | Sony Pictures Releasing | false | false |
| 67 | 63 | The Band's Visit | $54 | -60% | 1 | -1 | $54 | $136,627 | 12 | Alfa Films | false | false |
| 68 | - | The Nest | $51 | - | 1 | - | $51 | $1,003,891 | 23 | Distribution Company | false | false |
| 69 | 62 | Leonera | $50 | -63.2% | 1 | - | $50 | $500,324 | 18 | Walt Disney Pictures | false | false |
| 70 | 66 | I Served the King of England | $35 | -54.5% | 1 | -2 | $35 | $69,163 | 9 | Distribution Company | false | false |
