| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Mamma Mia! | $2,593,254 | - | 400 | - | $6,483 | $2,593,254 | 1 | United International Pictures | true | false |
| 2 | 1 | The Mummy: Tomb of the Dragon Emperor | $1,739,549 | -45% | 463 | -3 | $3,757 | $5,733,252 | 2 | Universal Pictures International (UPI) | false | false |
| 3 | - | You Don't Mess with the Zohan | $1,374,671 | - | 220 | - | $6,248 | $1,374,671 | 1 | Sony Pictures Releasing | true | false |
| 4 | 2 | Righteous Kill | $1,064,755 | -32.2% | 343 | -19 | $3,104 | $3,251,059 | 2 | 01 Distribution | false | false |
| 5 | 3 | Burn After Reading | $925,414 | -41% | 285 | -136 | $3,247 | $6,847,449 | 3 | Medusa Distribuzione | false | false |
| 6 | 4 | Hancock | $621,347 | -56.3% | 262 | -328 | $2,371 | $17,282,647 | 4 | Sony Pictures Releasing | false | false |
| 7 | - | Miracle at St. Anna | $596,624 | - | 263 | - | $2,268 | $596,624 | 1 | 01 Distribution | true | false |
| 8 | - | Noah's Ark | $536,014 | - | 233 | - | $2,300 | $536,778 | 1 | Eagle Pictures | true | false |
| 9 | 5 | Kung Fu Panda | $363,972 | -52.6% | 179 | -116 | $2,033 | $23,512,935 | 6 | Universal Pictures International (UPI) | false | false |
| 10 | - | Mirrors | $309,642 | - | 178 | - | $1,739 | $309,642 | 1 | 20th Century Fox International | true | false |
| 11 | 8 | Mid-August Lunch | $241,337 | -26% | 96 | -20 | $2,513 | $2,055,267 | 5 | Fandango | false | false |
| 12 | 6 | Giovanna's Father | $228,843 | -57.2% | 115 | -145 | $1,989 | $4,347,210 | 4 | Medusa Distribuzione | false | false |
| 13 | 7 | Fireflies in the Garden 2008 Re-release | $202,880 | -53.4% | 143 | -31 | $1,418 | $797,548 | 2 | Medusa Distribuzione | false | false |
| 14 | 10 | Paris | $140,971 | -22.8% | 65 | - | $2,168 | $403,350 | 2 | BIM Distribuzione | false | false |
| 15 | 11 | Lorna's Silence | $73,634 | -19.6% | 35 | -4 | $2,103 | $365,960 | 3 | Lucky Red | false | false |
| 16 | 9 | A Perfect Day | $51,575 | -73.8% | 41 | -87 | $1,257 | $4,245,677 | 5 | 01 Distribution | false | false |
| 17 | 12 | Il seme della discordia | $30,259 | -62.7% | 22 | -29 | $1,375 | $1,416,158 | 5 | Medusa Distribuzione | false | false |
| 18 | 16 | Pa-ra-da | $23,137 | -36.4% | 20 | -16 | $1,156 | $187,438 | 3 | 01 Distribution | false | false |
| 19 | 22 | Three Monkeys | $12,030 | -10% | 8 | -3 | $1,503 | $165,457 | 4 | BIM Distribuzione | false | false |
| 20 | 20 | Birdwatchers | $10,741 | -37.5% | 13 | -10 | $826 | $422,762 | 5 | 01 Distribution | false | false |
| 21 | 14 | The Chronicles of Narnia: Prince Caspian | $10,185 | -83.8% | 15 | -49 | $679 | $11,778,030 | 8 | Walt Disney Pictures | false | false |
| 22 | 21 | Gomorrah | $9,026 | -37.9% | 5 | -1 | $1,805 | $17,615,390 | 21 | 01 Distribution | false | false |
| 23 | 13 | Star Wars: The Clone Wars | $8,676 | -88.9% | 22 | -132 | $394 | $449,109 | 3 | Warner Bros. | false | false |
| 24 | 19 | Machan | $8,242 | -54% | 9 | -8 | $915 | $169,093 | 4 | Mikado Film | false | false |
| 25 | 17 | Everyone's Hero | $6,842 | -81% | 22 | -36 | $311 | $472,343 | 4 | Medusa Distribuzione | false | false |
| 26 | 18 | Virgin Territory | $6,771 | -77.9% | 6 | -28 | $1,128 | $1,567,471 | 5 | Eagle Pictures | false | false |
| 27 | 24 | La rabbia di Pasolini | $4,744 | -30.1% | 4 | -3 | $1,186 | $115,182 | 5 | Istituto Luce | false | false |
| 28 | 28 | Billo - Il Grand Dakhaar | $3,777 | +4.9% | 2 | - | $1,888 | $21,023 | 3 | N/A | false | false |
| 29 | - | Ex Drummer | $3,229 | - | 7 | - | $461 | $3,229 | 1 | L'Altrofilm | true | false |
| 30 | 29 | Il Divo | $2,184 | -38.8% | 5 | +2 | $436 | $8,510,788 | 19 | Lucky Red | false | false |
| 31 | 32 | The Wind Blows Round | $1,765 | +29% | 2 | +1 | $882 | $677,498 | 75 | Aranciafilm | false | false |
| 32 | - | Haïti chérie | $1,614 | - | 1 | - | $1,614 | $5,967 | 2 | N/A | false | false |
| 33 | - | The Nightmare Before Christmas 1994 Re-release | $986 | - | 1 | - | $986 | $1,045,455 | - | Walt Disney Pictures | - | false |
| 34 | 31 | La fabbrica dei tedeschi | $870 | -42.2% | 3 | - | $290 | $15,318 | 4 | Istituto Luce | false | false |
| 35 | 23 | The Dark Knight | $867 | -89.7% | 1 | -10 | $867 | $13,850,130 | 11 | Warner Bros. | false | false |
| 36 | - | La rabbia | $854 | - | 1 | - | $854 | $383,975 | 32 | L'Altrofilm | false | false |
| 37 | 30 | Meet Dave | $838 | -55% | 1 | -3 | $838 | $2,126,212 | 7 | 20th Century Fox International | false | false |
| 38 | - | The Night of the Sunflowers | $650 | - | 1 | - | $650 | $68,270 | 17 | Istituto Luce | false | false |
| 39 | - | Eldorado | $632 | - | 1 | - | $632 | $41,639 | 6 | Archibald | false | false |
| 40 | 15 | The Rocker | $613 | -99% | 1 | -89 | $613 | $397,592 | 3 | 20th Century Fox International | false | false |
| 41 | 33 | Taken | $582 | -53.5% | 2 | -1 | $291 | $2,010,445 | 8 | 20th Century Fox International | false | false |
| 42 | - | Then She Found Me | $562 | - | 1 | - | $562 | $940,111 | 18 | Medusa Distribuzione | false | false |
| 43 | 25 | La canarina assassinata | $527 | -90.2% | 2 | - | $263 | $8,434 | 2 | N/A | false | false |
| 44 | - | The Darjeeling Limited | $475 | - | 1 | - | $475 | $1,015,538 | 23 | 20th Century Fox International | false | false |
| 45 | - | Alexandra | $434 | - | 1 | - | $434 | $70,485 | 19 | N/A | false | false |
| 46 | - | Gravehopping | $376 | - | 1 | - | $376 | $23,367 | 14 | N/A | false | false |
| 47 | - | The Incredible Hulk | $291 | - | 1 | - | $291 | $6,201,003 | 16 | Universal Pictures International (UPI) | false | false |
| 48 | 44 | Invincible 2008 Re-release | $202 | -49.9% | 1 | - | $202 | $31,044 | 11 | Ripley's Film | false | false |
| 49 | - | Woman's Hearts | $182 | - | 1 | - | $182 | $66,253 | 17 | N/A | false | false |
| 50 | - | The Tree of Wooden Clogs | $154 | - | 1 | - | $154 | $7,790 | 1 | Istituto Luce | true | false |
