| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Mamma Mia! | $92,675 | - | 37 | - | $2,504 | $97,894 | 1 | United International Pictures | true | false |
| 2 | 1 | Mirrors | $72,063 | +12% | 26 | - | $2,771 | $305,674 | 3 | 20th Century Fox International | false | false |
| 3 | 2 | El Regalo | $50,170 | +4.9% | 37 | -1 | $1,355 | $208,750 | 3 | - | false | false |
| 4 | 3 | Tropic Thunder | $44,971 | +3.5% | 22 | +2 | $2,044 | $127,430 | 2 | United International Pictures | false | false |
| 5 | 4 | Journey to the Center of the Earth | $43,019 | +9.6% | 36 | - | $1,194 | $1,630,748 | 11 | Warner Bros. | false | false |
| 6 | 5 | Space Chimps | $37,488 | +16.7% | 22 | - | $1,704 | $148,812 | 3 | Bazuca Films | false | false |
| 7 | - | Awake | $22,459 | - | 13 | - | $1,727 | $22,459 | 1 | Bazuca Films | true | false |
| 8 | 6 | Nights in Rodanthe | $21,618 | -21.8% | 13 | - | $1,662 | $101,517 | 3 | Warner Bros. | false | false |
| 9 | 8 | Before the Devil Knows You're Dead | $19,246 | -1% | 9 | - | $2,138 | $46,629 | 2 | Bazuca Films | false | false |
| 10 | 7 | You Don't Mess with the Zohan | $18,826 | -31.3% | 27 | -3 | $697 | $487,806 | 6 | Sony Pictures Releasing | false | false |
| 11 | 9 | Taken | $14,658 | -0.7% | 16 | - | $916 | $245,298 | 7 | 20th Century Fox International | false | false |
| 12 | 10 | The Mist | $12,580 | +12.1% | 14 | +2 | $898 | $183,588 | 6 | Bazuca Films | false | false |
| 13 | 12 | Eagle Eye | $7,167 | -5.3% | 13 | -9 | $551 | $82,242 | 4 | United International Pictures | false | false |
| 14 | - | Conversations with My Gardener | $6,950 | - | 4 | - | $1,737 | $6,950 | 1 | Transeuropa | true | false |
| 15 | 13 | Death at a Funeral | $5,729 | -17.5% | 4 | -2 | $1,432 | $147,941 | 9 | Impacto Cine | false | false |
| 16 | 11 | Babylon A.D. | $5,370 | -34.9% | 11 | -1 | $488 | $105,340 | 5 | 20th Century Fox International | false | false |
| 17 | 16 | Meet Dave | $4,495 | -0.2% | 7 | -10 | $642 | $256,642 | 9 | 20th Century Fox International | false | false |
| 18 | 15 | We Own the Night | $4,166 | -18.5% | 6 | - | $694 | $48,896 | 4 | CDI Films | false | false |
| 19 | 18 | The Mummy: Tomb of the Dragon Emperor | $3,338 | -23.9% | 5 | +3 | $667 | $1,233,960 | 12 | United International Pictures | false | false |
| 20 | 19 | Secrets | $3,040 | -29.8% | 5 | -4 | $608 | $13,361 | 2 | - | false | false |
| 21 | 21 | Captivity | $2,828 | -5% | 8 | +1 | $353 | $166,333 | 10 | Bazuca Films | false | false |
| 22 | 14 | Tony Manero | $2,731 | -53.5% | 6 | -4 | $455 | $317,272 | 8 | Bazuca Films | false | false |
| 23 | 24 | Hannah Montana and Miley Cyrus: Best of Both Worlds Concert | $2,274 | -5.7% | 1 | - | $2,274 | $169,878 | 34 | Walt Disney Pictures | false | false |
| 24 | 17 | Caramel | $2,212 | -50% | 2 | -1 | $1,106 | $24,405 | 4 | Transeuropa | false | false |
| 25 | 22 | The Oxford Murders | $2,075 | -26.4% | 4 | -3 | $518 | $125,190 | 7 | Bazuca Films | false | false |
| 26 | - | El cielo, la tierra, y la lluvia | $1,892 | - | 3 | - | $630 | $1,892 | 1 | MC Film | true | false |
| 27 | 25 | The Good Life | $1,545 | -14% | 1 | - | $1,545 | $136,977 | 10 | N/A | false | false |
| 28 | 20 | Griffin & Phoenix | $1,438 | -59.1% | 4 | - | $359 | $48,097 | 5 | Bazuca Films | false | false |
| 29 | 28 | Kung Fu Panda | $1,230 | +70.8% | 7 | +4 | $175 | $2,498,069 | 15 | United International Pictures | false | false |
| 30 | 35 | The Orphanage | $600 | +140% | 1 | - | $600 | $622,788 | 25 | CDI Films | false | false |
| 31 | 31 | Cassandra's Dream | $497 | +33.6% | 2 | +1 | $248 | $53,089 | 8 | Transeuropa | false | false |
| 32 | 26 | Star Wars: The Clone Wars | $417 | -69.4% | 6 | +3 | $69 | $240,516 | 10 | Warner Bros. | false | false |
| 33 | 29 | Wanted | $310 | -33.6% | 1 | -1 | $310 | $418,922 | 10 | United International Pictures | false | false |
| 34 | 34 | Hellboy II: The Golden Army | $302 | +6% | 1 | - | $302 | $134,454 | 8 | United International Pictures | false | false |
| 35 | 37 | WALL·E | $236 | +11.8% | 5 | +3 | $47 | $3,311,078 | 17 | Walt Disney Pictures | false | false |
| 36 | 36 | 199 Tips to Be Happy | $143 | -36.4% | 2 | -1 | $71 | $15,915 | 4 | MC Film | false | false |
| 37 | 33 | 31 Minutos: La Película | $120 | -62.7% | 1 | - | $120 | $1,063,171 | 30 | MC Film | false | false |
| 38 | - | The Eye | $73 | - | 1 | - | $73 | $105,678 | 28 | United International Pictures | false | false |
| 39 | - | What Happens in Vegas | $67 | - | 1 | - | $67 | $291,906 | 21 | 20th Century Fox International | false | false |
| 40 | 23 | The Unknown Woman | $62 | -97.8% | 1 | -4 | $62 | $11,314 | 3 | Impacto Cine | false | false |
