| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Burn After Reading | $272,088 | - | 50 | - | $5,441 | $272,088 | 1 | United International Pictures | true | false |
| 2 | 1 | Beverly Hills Chihuahua | $197,885 | +16.4% | 52 | +1 | $3,805 | $1,097,745 | 3 | Walt Disney Pictures | false | false |
| 3 | 2 | The Bank Job | $121,936 | +0.2% | 33 | +1 | $3,695 | $291,967 | 2 | Alfa Films | false | false |
| 4 | 3 | Nights in Rodanthe | $75,023 | -13.1% | 49 | +1 | $1,531 | $773,774 | 4 | Warner Bros. | false | false |
| 5 | 5 | Mirrors | $60,178 | -1.5% | 35 | - | $1,719 | $534,614 | 4 | 20th Century Fox International | false | false |
| 6 | 4 | A Boyfriend for My Wife | $45,155 | -27% | 72 | -11 | $627 | $5,637,721 | 11 | Walt Disney Pictures | false | false |
| 7 | 6 | Appaloosa | $36,282 | -18.8% | 30 | - | $1,209 | $289,152 | 3 | Distribution Company | false | false |
| 8 | 7 | You Don't Mess with the Zohan | $33,550 | -22.3% | 29 | -1 | $1,156 | $676,663 | 6 | Sony Pictures Releasing | false | false |
| 9 | 8 | Hellboy II: The Golden Army | $32,412 | -21.1% | 40 | - | $810 | $266,683 | 3 | United International Pictures | false | false |
| 10 | 10 | Taken | $32,159 | -7% | 29 | -1 | $1,108 | $495,753 | 6 | 20th Century Fox International | false | false |
| 11 | 12 | Mamma Mia! | $23,572 | -10.2% | 42 | -6 | $561 | $1,537,186 | 10 | United International Pictures | false | false |
| 12 | 9 | Lakeview Terrace | $23,285 | -39.4% | 30 | - | $776 | $75,742 | 2 | Sony Pictures Releasing | false | false |
| 13 | - | Fast Food Nation | $22,111 | - | 14 | - | $1,579 | $22,111 | 1 | Impacto Cine | true | false |
| 14 | 11 | Tropic Thunder | $20,777 | -26.2% | 43 | -4 | $483 | $1,304,022 | 8 | United International Pictures | false | false |
| 15 | - | The Paranoids | $17,840 | - | 20 | - | $892 | $20,270 | 1 | Primer Plano Film Group | true | false |
| 16 | 13 | In Bruges | $17,417 | -30.9% | 19 | - | $916 | $245,385 | 4 | Distribution Company | false | false |
| 17 | 15 | Tinker Bell | $15,520 | +19.2% | 49 | -2 | $316 | $825,586 | 7 | Walt Disney Pictures | false | false |
| 18 | 14 | The Camera Obscura 2008 Re-release | $14,824 | -29% | 10 | - | $1,482 | $43,961 | 2 | Distribution Company | false | false |
| 19 | - | The Magic Flute | $14,201 | - | 10 | - | $1,420 | $14,201 | 1 | Distribution Company | true | false |
| 20 | - | Harold & Kumar Escape from Guantanamo Bay | $12,401 | - | 10 | - | $1,240 | $12,401 | 1 | Distribution Company | true | false |
| 21 | 21 | Journey to the Center of the Earth | $11,566 | +74.7% | 3 | - | $3,855 | $1,270,122 | 15 | Distribution Company | false | false |
| 22 | 17 | Manual of Love 2008 Re-release | $8,482 | -4.8% | 9 | - | $942 | $111,344 | 5 | Notro Films | false | false |
| 23 | 16 | My Brother is an Only Child | $7,539 | -36.7% | 11 | -2 | $685 | $232,907 | 6 | Alfa Films | false | false |
| 24 | 20 | REC | $6,730 | -18% | 14 | +1 | $480 | $237,453 | 7 | CDI Films | false | false |
| 25 | 18 | Dan in Real Life | $6,622 | -25% | 20 | -8 | $331 | $206,658 | 5 | Distribution Company | false | false |
| 26 | 19 | The Strangers | $6,146 | -28.1% | 15 | -12 | $409 | $354,767 | 7 | Distribution Company | false | false |
| 27 | 24 | Reasons for Not Falling in Love | $5,926 | +29.2% | 24 | +3 | $246 | $579,070 | 8 | Distribution Company | false | false |
| 28 | 23 | Still Life | $4,699 | -12.3% | 3 | +1 | $1,566 | $12,145 | 2 | 791 Cine | false | false |
| 29 | 22 | Days of Darkness | $3,563 | -44.3% | 4 | - | $890 | $12,810 | 2 | Alfa Films | false | false |
| 30 | 32 | Francesca | $2,412 | +17% | 4 | +1 | $603 | $181,452 | 15 | IFA | false | false |
| 31 | 35 | Irina Palm | $2,237 | +118.5% | 7 | +2 | $319 | $43,763 | 5 | Alfa Films | false | false |
| 32 | 25 | Eagle Eye | $2,104 | -51.9% | 14 | -11 | $150 | $178,366 | 5 | United International Pictures | false | false |
| 33 | 33 | Hannah Montana and Miley Cyrus: Best of Both Worlds Concert | $1,850 | +36.7% | 1 | - | $1,850 | $152,322 | 8 | Walt Disney Pictures | false | false |
| 34 | 28 | Four Minutes | $1,605 | -43.4% | 6 | - | $267 | $169,951 | 9 | Alfa Films | false | false |
| 35 | 30 | El cine de Maite | $1,594 | -25.9% | 5 | - | $318 | $4,621 | 2 | Primer Plano Film Group | false | false |
| 36 | 36 | The Headless Woman | $1,360 | +89.4% | 4 | - | $340 | $139,523 | 10 | Distribution Company | false | false |
| 37 | 26 | Superhero Movie | $1,335 | -57.3% | 5 | -11 | $267 | $328,183 | 7 | Pachamama Cine | false | false |
| 38 | 34 | Babylon A.D. | $1,069 | -1.7% | 5 | -5 | $213 | $216,353 | 8 | 20th Century Fox International | false | false |
| 39 | 27 | La próxima estación | $980 | -67.5% | 4 | -4 | $245 | $122,423 | 8 | Primer Plano Film Group | false | false |
| 40 | 29 | The Forbidden Kingdom | $904 | -64.8% | 5 | -13 | $180 | $101,028 | 4 | - | false | false |
| 41 | 37 | Wanted | $850 | +26.3% | 4 | -5 | $212 | $567,142 | 9 | United International Pictures | false | false |
| 42 | 42 | Nim's Island | $421 | +68.4% | 2 | -2 | $210 | $157,674 | 12 | United International Pictures | false | false |
| 43 | 31 | L'invité | $400 | -80.8% | 2 | -7 | $200 | $136,835 | 9 | Pachamama Cine | false | false |
| 44 | 40 | A Girl Cut in Two | $325 | -14.7% | 2 | - | $162 | $286,401 | 14 | Alfa Films | false | false |
| 45 | 49 | The Diving Bell and the Butterfly | $292 | +121.2% | 2 | +1 | $146 | $104,566 | 11 | Alfa Films | false | false |
| 46 | 48 | Conversations with My Gardener | $172 | +22.9% | 1 | - | $172 | $239,010 | 27 | Alfa Films | false | false |
| 47 | 43 | Kung Fu Panda | $170 | -30.6% | 2 | - | $85 | $5,607,395 | 17 | United International Pictures | false | false |
| 48 | 54 | Cassandra's Dream | $166 | +78.5% | 1 | - | $166 | $583,973 | 21 | Alfa Films | false | false |
| 49 | 46 | The Bottle | $126 | -34% | 2 | - | $63 | $85,814 | 7 | Primer Plano Film Group | false | false |
| 50 | 41 | WALL·E | $73 | -79.6% | 2 | -2 | $36 | $4,661,763 | 16 | Walt Disney Pictures | false | false |
| 51 | - | Black Sheep | $64 | - | 1 | - | $64 | $148,517 | 10 | Pachamama Cine | false | false |
| 52 | 58 | Valentina: The Movie | $61 | -3.2% | 1 | - | $61 | $367,315 | 16 | Pachamama Cine | false | false |
| 53 | 65 | The Chronicles of Narnia: Prince Caspian | $42 | +281.8% | 1 | - | $42 | $3,702,105 | 20 | Walt Disney Pictures | false | false |
| 54 | 59 | Comedy of Innocence | $38 | -36.7% | 1 | - | $38 | $20,045 | 366 | Primer Plano Film Group | false | false |
| 55 | 61 | Abrígate | $33 | -8.3% | 1 | - | $33 | $3,124 | 7 | Walt Disney Pictures | false | false |
| 56 | 52 | Viva High School Musical | $31 | -70.2% | 1 | -1 | $31 | $1,766,872 | 15 | Walt Disney Pictures | false | false |
| 57 | 39 | U2 3D | $21 | -95.1% | 1 | - | $21 | $153,890 | 31 | IMAX | false | false |
| 58 | 66 | Los superagentes, nueva generación | $8 | +14.3% | 1 | - | $8 | $864,484 | 15 | Argentina Sono Film S.A.C.I. | false | false |
| 59 | 67 | Meet Dave | $7 | +75% | 1 | -1 | $7 | $286,136 | 12 | 20th Century Fox International | false | false |
