| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Mamma Mia! | $63,630 | +34.7% | 36 | +12 | $1,767 | $220,137 | 3 | United International Pictures | false | false |
| 2 | 2 | El Regalo | $61,301 | +45.7% | 34 | +11 | $1,802 | $340,190 | 5 | - | false | false |
| 3 | 3 | The Nightmare Before Christmas 2009 3D Release | $56,497 | +69.1% | 3 | - | $18,832 | $94,502 | 2 | Walt Disney Pictures | false | false |
| 4 | 5 | Mirrors | $53,877 | +74% | 26 | +10 | $2,072 | $364,080 | 5 | 20th Century Fox International | false | false |
| 5 | - | REC | $37,890 | - | 17 | - | $2,228 | $37,890 | 1 | CDI Films | true | false |
| 6 | - | The Other Boleyn Girl | $31,736 | - | 12 | - | $2,644 | $31,736 | 1 | Bazuca Films | true | false |
| 7 | 6 | Blindness | $27,167 | +29.7% | 26 | +9 | $1,044 | $54,994 | 2 | 20th Century Fox International | false | false |
| 8 | 7 | Space Chimps | $26,614 | +39.6% | 20 | +11 | $1,330 | $175,249 | 5 | Bazuca Films | false | false |
| 9 | - | Nim's Island | $26,387 | - | 12 | - | $2,198 | $26,387 | 1 | United International Pictures | true | false |
| 10 | 8 | Tropic Thunder | $25,687 | +45.8% | 20 | +8 | $1,284 | $162,234 | 4 | United International Pictures | false | false |
| 11 | 10 | Journey to the Center of the Earth | $24,615 | +70.2% | 29 | +7 | $848 | $1,403,810 | 13 | Warner Bros. | false | false |
| 12 | 9 | 88 Minutes | $19,816 | +22.9% | 17 | +6 | $1,165 | $41,454 | 2 | Bazuca Films | false | false |
| 13 | 13 | Nights in Rodanthe | $12,551 | +45.4% | 13 | +8 | $965 | $121,684 | 5 | Warner Bros. | false | false |
| 14 | 11 | Before the Devil Knows You're Dead | $12,469 | +14.6% | 8 | +4 | $1,558 | $73,048 | 4 | Bazuca Films | false | false |
| 15 | 12 | Awake | $10,444 | +8.3% | 12 | +7 | $870 | $48,192 | 3 | Bazuca Films | false | false |
| 16 | - | The Diving Bell and the Butterfly | $7,170 | - | 5 | - | $1,434 | $7,170 | 1 | Transeuropa | true | false |
| 17 | 16 | The Mist | $4,421 | -2% | 12 | +4 | $368 | $197,103 | 8 | Bazuca Films | false | false |
| 18 | 17 | Death at a Funeral | $4,325 | +25% | 2 | - | $2,162 | $158,700 | 11 | Impacto Cine | false | false |
| 19 | 15 | Taken | $4,030 | -27.9% | 5 | -1 | $806 | $261,800 | 9 | 20th Century Fox International | false | false |
| 20 | 14 | You Don't Mess with the Zohan | $3,619 | -38.1% | 9 | -5 | $402 | $503,856 | 8 | Sony Pictures Releasing | false | false |
| 21 | - | Vitus | $3,109 | - | 4 | - | $777 | $3,109 | 1 | - | true | false |
| 22 | 19 | Babylon A.D. | $2,769 | +13.6% | 8 | - | $346 | $95,363 | 7 | 20th Century Fox International | false | false |
| 23 | 22 | Meet Dave | $2,083 | +61.6% | 4 | -2 | $520 | $217,869 | 11 | 20th Century Fox International | false | false |
| 24 | 20 | Eagle Eye | $1,802 | -10.1% | 8 | +1 | $225 | $75,019 | 6 | United International Pictures | false | false |
| 25 | 25 | We Own the Night | $1,026 | +18.8% | 2 | -3 | $513 | $52,644 | 6 | CDI Films | false | false |
| 26 | 18 | Conversations with My Gardener | $610 | -80.3% | 2 | - | $305 | $11,811 | 3 | Transeuropa | false | false |
| 27 | 21 | Captivity | $576 | -55.6% | 3 | -2 | $192 | $169,465 | 12 | Bazuca Films | false | false |
