| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Quantum of Solace | $25,309,345 | - | 540 | - | $46,869 | $25,309,345 | 1 | Sony Pictures Releasing | true | false |
| 2 | 1 | High School Musical 3: Senior Year | $4,406,623 | -67.1% | 474 | -19 | $9,296 | $28,570,731 | 2 | Walt Disney Pictures | false | false |
| 3 | 2 | Saw V | $1,531,808 | -60.5% | 367 | - | $4,173 | $7,441,587 | 2 | Lionsgate Films | false | false |
| 4 | 4 | Ghost Town | $1,263,962 | -41.1% | 345 | +2 | $3,663 | $5,516,576 | 2 | Paramount Pictures International | false | false |
| 5 | 3 | Burn After Reading | $882,514 | -61.3% | 350 | -45 | $2,521 | $9,747,971 | 3 | Universal Pictures International (UPI) | false | false |
| 6 | 6 | Igor | $558,573 | -22.3% | 416 | -30 | $1,342 | $5,216,327 | 4 | Momentum Pictures | false | false |
| 7 | - | Golmaal Returns | $309,836 | - | 42 | - | $7,377 | $309,836 | 1 | Studio 18 | true | false |
| 8 | 5 | Eagle Eye | $261,925 | -76.3% | 287 | -75 | $912 | $4,937,993 | 3 | Paramount Pictures International | false | false |
| 9 | 9 | Mamma Mia! | $229,216 | -44.1% | 189 | -95 | $1,212 | $108,258,001 | 17 | Universal Pictures International (UPI) | false | false |
| 10 | - | Hunger | $219,173 | - | 68 | - | $3,223 | $219,173 | 1 | Pathé | true | false |
| 11 | 7 | The House Bunny | $111,073 | -77.1% | 196 | -126 | $566 | $4,709,335 | 4 | Sony Pictures Releasing | false | false |
| 12 | - | Of Time and the City | $91,894 | - | 25 | - | $3,675 | $91,894 | 1 | British Film Institute (BFI) | true | false |
| 13 | 8 | Taken | $87,563 | -78.9% | 112 | -117 | $781 | $9,715,400 | 6 | 20th Century Fox International | false | false |
| 14 | 10 | Mirrors | $78,099 | -78.3% | 121 | -128 | $645 | $4,209,552 | 4 | 20th Century Fox International | false | false |
| 15 | 12 | The Boy in the Striped Pajamas | $76,645 | -56.5% | 83 | -49 | $923 | $6,810,003 | 8 | Walt Disney Pictures | false | false |
| 16 | 15 | Gomorrah | $74,529 | -48.7% | 29 | -8 | $2,569 | $1,166,049 | 4 | Optimum Releasing | false | false |
| 17 | 26 | Space Chimps | $64,341 | +98.5% | 132 | +49 | $487 | $6,645,010 | 14 | Entertainment Film Distributors | false | false |
| 18 | 18 | Fly Me to the Moon 3D | $58,523 | -27.5% | 31 | -33 | $1,887 | $1,445,786 | 5 | Momentum Pictures | false | false |
| 19 | 14 | City of Ember | $49,332 | -69.7% | 137 | -202 | $360 | $2,204,103 | 4 | Entertainment Film Distributors | false | false |
| 20 | 13 | Heroes | $49,214 | -71.1% | 22 | -2 | $2,237 | $317,224 | 2 | Eros Worldwide | false | false |
| 21 | 17 | I've Loved You So Long | $47,815 | -50.9% | 18 | -12 | $2,656 | $1,524,568 | 6 | Lionsgate Films | false | false |
| 22 | - | Fashion | $33,715 | - | 14 | - | $2,408 | $33,715 | 1 | UTV Motion Pictures | true | false |
| 23 | - | The Midnight Meat Train | $32,847 | - | 48 | - | $684 | $32,847 | 1 | Lionsgate Films | true | false |
| 24 | 11 | How to Lose Friends & Alienate People | $23,316 | -91% | 41 | -139 | $568 | $6,515,577 | 5 | Paramount Pictures International | false | false |
| 25 | 23 | The Duchess | $21,215 | -43.5% | 13 | -7 | $1,631 | $11,745,010 | 9 | Pathé | false | false |
| 26 | 30 | Kung Fu Panda | $20,300 | -16.8% | 86 | - | $236 | $32,185,848 | 18 | Paramount Pictures International | false | false |
| 27 | 19 | Brideshead Revisited | $19,422 | -65.5% | 17 | -28 | $1,142 | $2,074,677 | 5 | Walt Disney Pictures | false | false |
| 28 | 21 | Roadside Romeo | $16,305 | -67.6% | 15 | -8 | $1,087 | $106,718 | 2 | Yash Raj Films | false | false |
| 29 | 29 | The Dark Knight | $15,182 | -42.3% | 9 | -3 | $1,686 | $88,648,001 | 15 | Warner Bros. | false | false |
| 30 | 22 | WALL·E | $14,328 | -67.3% | 42 | -64 | $341 | $41,115,901 | 16 | Walt Disney Pictures | false | false |
| 31 | 16 | Tropic Thunder | $14,250 | -85.7% | 20 | -78 | $712 | $13,800,970 | 7 | Paramount Pictures International | false | false |
| 32 | 24 | Quiet Chaos | $13,393 | -62.6% | 9 | -3 | $1,488 | $73,957 | 2 | New Wave Films | false | false |
| 33 | 32 | Journey to the Center of the Earth | $12,604 | -15% | 71 | -11 | $177 | $6,054,786 | 17 | Entertainment Film Distributors | false | false |
| 34 | 31 | The Fox and the Child | $9,136 | -57.8% | 68 | -26 | $134 | $1,117,883 | 13 | Pathé | false | false |
| 35 | 27 | A Film with Me in It | $8,710 | -72.9% | 10 | -15 | $871 | $134,062 | 3 | N/A | false | false |
| 36 | 25 | Aegan | $8,631 | -75.5% | 5 | -8 | $1,726 | $69,624 | 2 | Ayngaran International | false | false |
| 37 | 46 | The Fall | $3,724 | +35.1% | 3 | +1 | $1,241 | $112,114 | 5 | Momentum Pictures | false | false |
| 38 | 60 | Miss Pettigrew Lives for a Day | $3,544 | +236.6% | 3 | +1 | $1,181 | $780,511 | 12 | Momentum Pictures | false | false |
| 39 | 59 | Man on Wire | $3,522 | +233.5% | 4 | +1 | $880 | $1,564,100 | 14 | Icon Film Distribution | false | false |
| 40 | 20 | The Rocker | $3,445 | -93.7% | 19 | -168 | $181 | $640,283 | 3 | 20th Century Fox International | false | false |
| 41 | - | Stone of Destiny | $3,360 | - | 4 | - | $840 | $240,104 | - | - | - | false |
| 42 | 34 | Righteous Kill | $3,331 | -76.7% | 4 | -12 | $832 | $3,625,001 | 6 | Lionsgate Films | false | false |
| 43 | 36 | Nights in Rodanthe | $2,484 | -79.8% | 7 | -13 | $354 | $799,960 | 4 | Warner Bros. | false | false |
| 44 | 35 | The Zone | $2,322 | -81.9% | 1 | -6 | $2,322 | $45,885 | 3 | Soda Pictures | false | false |
| 45 | 44 | Disaster Movie | $2,103 | -43.3% | 8 | -11 | $262 | $5,398,001 | 9 | Momentum Pictures | false | false |
| 46 | 48 | Somers Town | $1,947 | -26.5% | 3 | +1 | $649 | $979,000 | 11 | Optimum Releasing | false | false |
| 47 | 43 | Unrelated | $1,756 | -60.6% | 3 | -3 | $585 | $146,618 | 7 | New Wave Films | false | false |
| 48 | 76 | Female Agents | $1,742 | +5,343.8% | 1 | - | $1,742 | $501,678 | 19 | Revolver Entertainment | false | false |
| 49 | 54 | Times and Winds | $1,737 | -5.4% | 1 | -2 | $1,737 | $122,042 | 10 | Artificial Eye | false | false |
| 50 | 39 | Linha de Passe | $1,324 | -81.6% | 1 | -8 | $1,324 | $234,712 | 7 | Pathé | false | false |
| 51 | 49 | Wild Child | $1,303 | -50% | 8 | -8 | $162 | $8,235,794 | 12 | Universal Pictures International (UPI) | false | false |
| 52 | 78 | The Edge of Love | $1,139 | +3,459.4% | 1 | - | $1,139 | $2,423,788 | 20 | Lionsgate Films | false | false |
| 53 | 51 | Fear(s) of the Dark | $964 | -58.1% | 2 | -2 | $482 | $8,647 | 2 | - | false | false |
| 54 | - | Hellboy II: The Golden Army | $950 | - | 2 | - | $475 | $13,921,451 | 11 | Universal Pictures International (UPI) | false | false |
| 55 | 63 | Jar City | $905 | +8.5% | 3 | +1 | $301 | $216,918 | 8 | The Works UK Distribution | false | false |
| 56 | 68 | Meet Dave | $900 | +109.3% | 7 | +3 | $128 | $2,719,659 | 16 | 20th Century Fox International | false | false |
| 57 | 47 | The Pope's Toilet | $664 | -75.1% | 2 | -1 | $332 | $168,380 | 14 | Soda Pictures | false | false |
| 58 | 41 | Seval | $646 | -90% | 2 | -1 | $323 | $17,600 | 2 | Ayngaran International | false | false |
| 59 | 50 | Outlander | $530 | -78% | 1 | - | $530 | $3,313 | 2 | - | false | false |
| 60 | 75 | Mongol: The Rise of Genghis Khan | $498 | +1,456.2% | 1 | - | $498 | $1,523,089 | 22 | The Works UK Distribution | false | false |
| 61 | 33 | The Wave | $466 | -96.7% | 2 | -7 | $233 | $164,900 | 7 | Momentum Pictures | false | false |
| 62 | 77 | Then She Found Me | $426 | +1,231.2% | 2 | +1 | $213 | $204,112 | 7 | Chelsea Films | false | false |
| 63 | 55 | Badlands | $370 | -78.2% | 1 | - | $370 | $54,248 | 10 | British Film Institute (BFI) | false | false |
| 64 | 40 | Death Race | $357 | -94.7% | 4 | -18 | $89 | $3,330,784 | 6 | Universal Pictures International (UPI) | false | false |
| 65 | 73 | The Wackness | $299 | +160% | 2 | +1 | $149 | $421,300 | 10 | Revolver Entertainment | false | false |
| 66 | 28 | Incendiary | $267 | -99.1% | 5 | -11 | $53 | $45,482 | 2 | Optimum Releasing | false | false |
| 67 | 67 | Paris | $228 | -62.1% | 1 | - | $228 | $243,455 | 15 | Optimum Releasing | false | false |
| 68 | 71 | Grease 2008 Re-release | $227 | -18.1% | 1 | -2 | $227 | $169,089 | 7 | Park Circus | false | false |
| 69 | 58 | Young@Heart | $206 | -84.1% | 1 | -3 | $206 | $7,360 | 3 | - | false | false |
| 70 | 57 | Alexandra | $186 | -87.1% | 1 | -2 | $186 | $26,353 | 6 | Artificial Eye | false | false |
| 71 | 42 | Pineapple Express | $181 | -96.5% | 2 | -8 | $90 | $6,979,618 | 8 | Sony Pictures Releasing | false | false |
| 72 | - | The Mummy: Tomb of the Dragon Emperor | $161 | - | 1 | - | $161 | $21,633,063 | 13 | Universal Pictures International (UPI) | false | false |
| 73 | 72 | Saviours | $159 | +5.3% | 2 | +1 | $79 | $20,451 | 5 | Eclipse Pictures | false | false |
| 74 | 66 | Ashes of Time | $82 | -86.9% | 1 | -1 | $82 | $13,728 | 8 | Artificial Eye | false | false |
| 75 | - | The Banishment | $32 | - | 1 | - | $32 | $53,832 | 12 | Artificial Eye | false | false |
| 76 | 56 | Import Export | $32 | -97.9% | 1 | -2 | $32 | $42,384 | 5 | Trinity Filmed Entertainment | false | false |
