| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Quantum of Solace | $386,335 | - | 124 | - | $3,115 | $386,335 | 1 | Sony Pictures Releasing | true | false |
| 2 | 1 | Saw V | $192,454 | -38.7% | 60 | +1 | $3,207 | $582,454 | 2 | Walt Disney Pictures | false | false |
| 3 | 2 | Burn After Reading | $103,739 | -34.5% | 51 | +2 | $2,034 | $623,868 | 3 | United International Pictures | false | false |
| 4 | 3 | Beverly Hills Chihuahua | $91,062 | -16.9% | 61 | +4 | $1,492 | $1,285,422 | 5 | Walt Disney Pictures | false | false |
| 5 | - | Flawless | $64,723 | - | 21 | - | $3,082 | $64,723 | 1 | Distribution Company | true | false |
| 6 | 4 | The Bank Job | $44,642 | -41.8% | 34 | +1 | $1,313 | $432,427 | 4 | Alfa Films | false | false |
| 7 | 8 | The Nightmare Before Christmas 2009 3D Release | $43,628 | +0.1% | 3 | - | $14,542 | $110,255 | 2 | Walt Disney Pictures | false | false |
| 8 | 7 | Nights in Rodanthe | $30,721 | -34.9% | 48 | -1 | $640 | $831,710 | 6 | Warner Bros. | false | false |
| 9 | 5 | The Women | $29,307 | -48.9% | 36 | -5 | $814 | $101,485 | 2 | CDI Films | false | false |
| 10 | 6 | Blindness | $28,307 | -48.5% | 31 | +1 | $913 | $98,011 | 2 | 20th Century Fox International | false | false |
| 11 | 9 | Mirrors | $23,388 | -27.2% | 33 | -2 | $708 | $571,154 | 6 | 20th Century Fox International | false | false |
| 12 | 13 | Taken | $11,593 | -31.2% | 27 | -1 | $429 | $499,785 | 8 | 20th Century Fox International | false | false |
| 13 | - | Disco | $11,246 | - | 10 | - | $1,124 | $11,246 | 1 | Pachamama Cine | true | false |
| 14 | 12 | You Don't Mess with the Zohan | $9,096 | -46% | 26 | -4 | $349 | $712,064 | 8 | Sony Pictures Releasing | false | false |
| 15 | 14 | Shara | $8,193 | -48.1% | 7 | - | $1,170 | $27,110 | 2 | Zeta Films | false | false |
| 16 | 11 | Appaloosa | $7,906 | -54.6% | 27 | -1 | $292 | $306,617 | 5 | Distribution Company | false | false |
| 17 | 16 | Mamma Mia! | $5,642 | -57.1% | 19 | -19 | $296 | $1,453,423 | 12 | United International Pictures | false | false |
| 18 | 22 | In Bruges | $5,636 | -27.3% | 15 | -4 | $375 | $247,071 | 6 | Distribution Company | false | false |
| 19 | 15 | Hellboy II: The Golden Army | $5,489 | -61.2% | 30 | -9 | $182 | $277,874 | 5 | United International Pictures | false | false |
| 20 | 23 | Fast Food Nation | $5,440 | -19.9% | 13 | - | $418 | $38,483 | 3 | Impacto Cine | false | false |
| 21 | 10 | A Boyfriend for My Wife | $5,229 | -70.5% | 26 | -23 | $201 | $5,651,030 | 13 | Walt Disney Pictures | false | false |
| 22 | 25 | Incómodos | $3,835 | -27.9% | 5 | - | $767 | $11,073 | 2 | Primer Plano Film Group | false | false |
| 23 | 21 | The Camera Obscura 2008 Re-release | $3,607 | -54.7% | 6 | -3 | $601 | $57,921 | 4 | Distribution Company | false | false |
| 24 | 20 | Tinker Bell | $3,591 | -55.5% | 35 | -12 | $102 | $783,734 | 9 | Walt Disney Pictures | false | false |
| 25 | 19 | Tropic Thunder | $3,550 | -64.5% | 19 | -11 | $186 | $1,227,472 | 10 | United International Pictures | false | false |
| 26 | 28 | Harold & Kumar Escape from Guantanamo Bay | $2,738 | -20.5% | 9 | -1 | $304 | $21,520 | 3 | Distribution Company | false | false |
| 27 | 26 | Manual of Love 2008 Re-release | $2,670 | -45.5% | 7 | -2 | $381 | $114,213 | 7 | Notro Films | false | false |
| 28 | 17 | Lakeview Terrace | $2,592 | -78.1% | 15 | -15 | $172 | $98,085 | 4 | Sony Pictures Releasing | false | false |
| 29 | 24 | The Paranoids | $2,488 | -55.5% | 5 | -3 | $497 | $32,578 | 3 | Primer Plano Film Group | false | false |
| 30 | 29 | My Brother is an Only Child | $1,863 | -36% | 7 | -1 | $266 | $223,418 | 8 | Alfa Films | false | false |
| 31 | - | Snow Cake 2008 Re-release | $1,857 | - | 3 | - | $619 | $1,857 | 1 | Distribution Company | true | false |
| 32 | - | Kill Them All | $1,495 | - | 3 | - | $498 | $1,495 | 1 | Primer Plano Film Group | true | false |
| 33 | 27 | The Magic Flute | $761 | -83.7% | 5 | -3 | $152 | $22,832 | 3 | Distribution Company | false | false |
| 34 | 30 | Still Life | $740 | -69.3% | 2 | -1 | $370 | $16,082 | 4 | 791 Cine | false | false |
| 35 | - | Behind the Sun, More Sky | $653 | - | 1 | - | $653 | $653 | 1 | N/A | true | false |
| 36 | 36 | La próxima estación | $530 | -39.5% | 6 | - | $88 | $116,367 | 10 | Primer Plano Film Group | false | false |
| 37 | 40 | Four Minutes | $492 | +14.2% | 3 | +1 | $164 | $158,679 | 11 | Alfa Films | false | false |
| 38 | 34 | REC | $428 | -71% | 5 | -4 | $85 | $223,496 | 9 | CDI Films | false | false |
| 39 | 18 | Don't Look Down | $221 | -97.9% | 2 | -17 | $110 | $14,001 | 2 | Primer Plano Film Group | false | false |
| 40 | 37 | Eagle Eye | $213 | -75.4% | 3 | -2 | $71 | $170,377 | 7 | United International Pictures | false | false |
| 41 | 42 | Superhero Movie | $176 | -37.1% | 1 | -1 | $176 | $334,873 | 9 | Pachamama Cine | false | false |
| 42 | 51 | Conversations with My Gardener | $157 | +554.2% | 1 | - | $157 | $239,299 | 29 | Alfa Films | false | false |
| 43 | 38 | Days of Darkness | $154 | -77.9% | 1 | -1 | $154 | $13,896 | 4 | Alfa Films | false | false |
| 44 | 43 | The Diving Bell and the Butterfly | $97 | -65.2% | 1 | -1 | $97 | $105,005 | 13 | Alfa Films | false | false |
| 45 | 46 | A Girl Cut in Two | $62 | -44.1% | 1 | - | $62 | $286,698 | 16 | Alfa Films | false | false |
| 46 | 32 | The Strangers | $47 | -97.3% | 1 | -6 | $47 | $355,107 | 9 | Distribution Company | false | false |
| 47 | 41 | The Forbidden Kingdom | $27 | -92.1% | 1 | -2 | $27 | $101,411 | 6 | - | false | false |
| 48 | 31 | Dan in Real Life | $20 | -99.1% | 1 | -9 | $20 | $206,788 | 7 | Distribution Company | false | false |
| 49 | 56 | Meet Dave | $17 | +183.3% | 1 | - | $17 | $264,944 | 14 | 20th Century Fox International | false | false |
| 50 | 33 | Reasons for Not Falling in Love | $5 | -99.7% | 1 | -8 | $5 | $540,326 | 10 | Distribution Company | false | false |
