| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Quantum of Solace | $154,842 | -40.4% | 55 | - | $2,815 | $461,228 | 2 | Sony Pictures Releasing | false | false |
| 2 | 2 | El Regalo | $39,759 | -4.2% | 33 | -2 | $1,204 | $457,457 | 7 | - | false | false |
| 3 | 3 | Mamma Mia! | $25,001 | -24.9% | 28 | -9 | $892 | $300,696 | 5 | United International Pictures | false | false |
| 4 | 5 | The Nightmare Before Christmas 2009 3D Release | $24,222 | -20.7% | 3 | - | $8,074 | $161,385 | 4 | Walt Disney Pictures | false | false |
| 5 | 4 | Mirrors | $23,131 | -25.8% | 25 | - | $925 | $445,532 | 7 | 20th Century Fox International | false | false |
| 6 | 6 | REC | $20,452 | -14% | 16 | +1 | $1,278 | $104,726 | 3 | CDI Films | false | false |
| 7 | - | Irma Vap: O Retorno | $19,401 | - | 15 | - | $1,293 | $19,401 | 1 | Bazuca Films | true | false |
| 8 | 7 | Space Chimps | $16,875 | -2.8% | 20 | - | $843 | $217,142 | 7 | Bazuca Films | false | false |
| 9 | 8 | The Other Boleyn Girl | $13,078 | -15.8% | 10 | -4 | $1,307 | $73,747 | 3 | Bazuca Films | false | false |
| 10 | 9 | Nim's Island | $11,109 | -20.9% | 12 | - | $925 | $57,285 | 3 | United International Pictures | false | false |
| 11 | 10 | Journey to the Center of the Earth | $9,137 | -30.1% | 20 | -4 | $456 | $1,449,590 | 15 | Warner Bros. | false | false |
| 12 | 11 | Blindness | $8,107 | -23.8% | 17 | -6 | $476 | $85,178 | 4 | 20th Century Fox International | false | false |
| 13 | 12 | Tropic Thunder | $7,806 | -15.4% | 19 | +4 | $410 | $188,507 | 6 | United International Pictures | false | false |
| 14 | 13 | 88 Minutes | $6,721 | -16.3% | 13 | -2 | $517 | $64,173 | 4 | Bazuca Films | false | false |
| 15 | - | A Secret | $6,520 | - | 5 | - | $1,304 | $6,520 | 1 | Transeuropa | true | false |
| 16 | - | Forbidden to Forbid 2008 Re-release | $5,146 | - | 5 | - | $1,029 | $5,146 | 1 | - | true | false |
| 17 | - | Chaos | $5,088 | - | 7 | - | $726 | $5,088 | 1 | Andes Films | true | false |
| 18 | 14 | Before the Devil Knows You're Dead | $4,312 | -32.5% | 5 | -4 | $862 | $89,124 | 6 | Bazuca Films | false | false |
| 19 | 17 | Awake | $4,120 | -28.7% | 11 | - | $374 | $63,755 | 5 | Bazuca Films | false | false |
| 20 | 15 | Nights in Rodanthe | $3,622 | -42.6% | 11 | -4 | $329 | $137,979 | 7 | Warner Bros. | false | false |
| 21 | 16 | My Blueberry Nights | $2,552 | -57.2% | 5 | -2 | $510 | $11,036 | 2 | Bazuca Films | false | false |
| 22 | 20 | The Mist | $2,443 | +47.2% | 6 | - | $407 | $200,783 | 10 | Bazuca Films | false | false |
| 23 | - | The Price to Pay | $2,095 | - | 5 | - | $419 | $6,601 | 2 | Impacto Cine | false | false |
| 24 | 18 | Babylon A.D. | $1,898 | -14.5% | 4 | -2 | $474 | $105,467 | 9 | 20th Century Fox International | false | false |
| 25 | 21 | Death at a Funeral | $1,056 | +4.2% | 1 | - | $1,056 | $161,783 | 13 | Impacto Cine | false | false |
| 26 | - | Eagle Eye | $283 | - | 1 | - | $283 | $88,953 | 8 | United International Pictures | false | false |
| 27 | - | The Orphanage | $206 | - | 1 | - | $206 | $733,144 | 29 | CDI Films | false | false |
| 28 | - | Horton Hears a Who! | $180 | - | 1 | - | $180 | $441,526 | 36 | 20th Century Fox International | false | false |
| 29 | - | The Mummy: Tomb of the Dragon Emperor | $144 | - | 1 | - | $144 | $1,434,116 | 16 | United International Pictures | false | false |
| 30 | - | Taken | $129 | - | 1 | - | $129 | $230,039 | 11 | 20th Century Fox International | false | false |
| 31 | - | Alvin and the Chipmunks | $112 | - | 1 | - | $112 | $608,834 | 48 | 20th Century Fox International | false | false |
| 32 | - | WALL·E | $108 | - | 2 | - | $54 | $3,312,300 | 21 | Walt Disney Pictures | false | false |
| 33 | - | 31 Minutos: La Película | $95 | - | 1 | - | $95 | $1,063,451 | 34 | MC Film | false | false |
| 34 | - | P2 | $61 | - | 1 | - | $61 | $41,312 | 25 | Bazuca Films | false | false |
| 35 | - | Star Wars: The Clone Wars | $20 | - | 1 | - | $20 | $241,004 | 14 | Warner Bros. | false | false |
| 36 | - | Meet Dave | $8 | - | 1 | - | $8 | $228,434 | 13 | 20th Century Fox International | false | false |
