| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Body of Lies | $321,482 | - | 20 | - | $16,074 | $321,482 | 1 | N/A | true | false |
| 2 | - | Saw V | $248,998 | - | 20 | - | $12,449 | $248,998 | 1 | N/A | true | false |
| 3 | 1 | Quantum of Solace | $141,243 | -58.8% | 15 | -10 | $9,416 | $1,783,935 | 3 | N/A | false | false |
| 4 | 3 | Open Season 2 | $52,325 | -46.5% | 16 | - | $3,270 | $162,806 | 2 | N/A | false | false |
| 5 | - | Ghost Town | $39,593 | - | 16 | - | $2,474 | $39,593 | 1 | N/A | true | false |
| 6 | - | Igor | $36,079 | - | 12 | - | $3,006 | $36,079 | 1 | N/A | true | false |
| 7 | 2 | Hero Wanted | $35,194 | -79.4% | 19 | -1 | $1,852 | $243,301 | 2 | N/A | false | false |
| 8 | - | Pineapple Express | $33,842 | - | 12 | - | $2,820 | $33,842 | 1 | N/A | true | false |
| 9 | 5 | Over Her Dead Body | $16,551 | -69.2% | 14 | - | $1,182 | $86,813 | 2 | N/A | false | false |
| 10 | 10 | High School Musical 3: Senior Year | $8,696 | -64.2% | 3 | -5 | $2,898 | $636,249 | 5 | Walt Disney Pictures | false | false |
| 11 | 8 | Bangkok Dangerous | $6,598 | -74.6% | 3 | -5 | $2,199 | $642,629 | 4 | N/A | false | false |
| 12 | 12 | Eagle Eye | $5,891 | -45.6% | 1 | -2 | $5,891 | $1,081,745 | 7 | N/A | false | false |
| 13 | 11 | Taken | $5,834 | -63.4% | 2 | -1 | $2,917 | $332,601 | 4 | N/A | false | false |
| 14 | 4 | Mongol: The Rise of Genghis Khan | $5,705 | -93.7% | 4 | -15 | $1,426 | $125,662 | 2 | N/A | false | false |
| 15 | 6 | Nights in Rodanthe | $3,026 | -93.8% | 1 | -12 | $3,026 | $71,021 | 2 | N/A | false | false |
| 16 | 9 | Amaliyat Khassa | $2,819 | -88.5% | 4 | -11 | $704 | $34,955 | 2 | N/A | false | false |
| 17 | 7 | Timber Falls | $1,624 | -94.1% | 3 | -14 | $541 | $172,371 | 3 | N/A | false | false |
| 18 | 20 | Dragon Hunters | $1,402 | +84.5% | 1 | - | $1,402 | $129,342 | 8 | N/A | false | false |
| 19 | 14 | Chaos, This Is | $1,075 | -58.3% | 1 | - | $1,075 | $44,606 | 3 | N/A | false | false |
| 20 | 23 | Space Chimps | $644 | +8.2% | 1 | - | $644 | $176,664 | 17 | N/A | false | false |
| 21 | 16 | Mamma Mia! | $513 | -65.8% | 1 | - | $513 | $577,966 | 20 | N/A | false | false |
| 22 | 22 | Death Race | $368 | -40% | 1 | - | $368 | $1,088,030 | 8 | N/A | false | false |
| 23 | 18 | Deception | $230 | -80.7% | 1 | - | $230 | $126,695 | 5 | N/A | false | false |
| 24 | 19 | Hassan wa Morcus | $172 | -78.6% | 1 | - | $172 | $465,272 | 8 | N/A | false | false |
