| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Body of Lies | $33,732 | - | 7 | - | $4,818 | $36,391 | 1 | Garsu Pasaulio Irasai | true | false |
| 2 | 1 | Quantum of Solace | $24,633 | -50.1% | 10 | - | $2,463 | $245,392 | 3 | ACME | false | false |
| 3 | 2 | Vicky Cristina Barcelona | $24,309 | -34.2% | 7 | +3 | $3,472 | $84,624 | 2 | ACME | false | false |
| 4 | - | The Ghost | $16,393 | - | 5 | - | $3,278 | $16,393 | 1 | ACME | true | false |
| 5 | 3 | The House Bunny | $9,980 | -36.7% | 6 | - | $1,663 | $106,405 | 4 | ACME | false | false |
| 6 | 4 | Nights in Rodanthe | $6,791 | -45.1% | 6 | - | $1,131 | $95,672 | 4 | Garsu Pasaulio Irasai | false | false |
| 7 | 7 | Sex Drive | $6,487 | -32.7% | 5 | -1 | $1,297 | $134,582 | 5 | ACME | false | false |
| 8 | 9 | Burn After Reading | $4,685 | +49.5% | 2 | - | $2,342 | $137,956 | 8 | ACME | false | false |
| 9 | 6 | Saw V | $4,195 | -65.1% | 7 | - | $599 | $162,678 | 4 | ACME | false | false |
| 10 | 5 | Lakeview Terrace | $3,558 | -70.9% | 3 | - | $1,186 | $20,052 | 2 | ACME | false | false |
| 11 | 8 | How to Lose Friends & Alienate People | $2,794 | -20.7% | 1 | - | $2,794 | $9,146 | 2 | N/A | false | false |
| 12 | 11 | Garfield: A Tail of Two Kitties | $1,310 | -34.4% | 2 | - | $655 | $358,900 | 122 | Universal Pictures International (UPI) | false | false |
| 13 | 12 | My Best Friend's Girl | $953 | -45.8% | 2 | -2 | $476 | $193,142 | 7 | ACME | false | false |
| 14 | - | Ice Age: The Meltdown | $791 | - | 3 | - | $263 | $605,405 | 138 | Universal Pictures International (UPI) | false | false |
| 15 | - | Ratatouille | $718 | - | 1 | - | $718 | $651,004 | 67 | Universal Pictures International (UPI) | false | false |
| 16 | - | Elegy | $674 | - | 1 | - | $674 | $22,236 | 5 | ACME | false | false |
| 17 | 15 | Sukiyaki Western Django | $645 | -51.6% | 1 | - | $645 | $5,612 | 3 | Universal Pictures International (UPI) | false | false |
| 18 | 16 | WALL·E | $580 | -50.4% | 1 | -1 | $580 | $409,571 | 19 | Universal Pictures International (UPI) | false | false |
| 19 | 18 | Max Payne | $426 | -57.2% | 3 | - | $142 | $156,927 | 6 | Universal Pictures International (UPI) | false | false |
| 20 | 14 | Admiral | $420 | -72.1% | 1 | -1 | $420 | $68,746 | 7 | ACME | false | false |
| 21 | 13 | Pineapple Express | $351 | -77.3% | 2 | +1 | $175 | $89,957 | 6 | ACME | false | false |
