| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Madagascar: Escape 2 Africa | $819,984 | -21.4% | 192 | +7 | $4,270 | $2,539,641 | 2 | Universal Pictures International (UPI) | false | false |
| 2 | 2 | Quantum of Solace | $691,021 | -31.8% | 135 | - | $5,118 | $6,677,673 | 4 | Sony Pictures Releasing | false | false |
| 3 | - | Winter in Wartime | $421,317 | - | 95 | - | $4,434 | $442,844 | 1 | Benelux Film Distributors | true | false |
| 4 | 4 | Sinterklaas en het geheim van het grote boek | $231,580 | -12.2% | 101 | - | $2,292 | $2,208,348 | 8 | RCV Film Distribution | false | false |
| 5 | 3 | Body of Lies | $211,104 | -20.3% | 60 | - | $3,518 | $586,321 | 2 | Warner Bros. | false | false |
| 6 | - | The Women | $143,485 | - | 58 | - | $2,473 | $321,011 | 1 | Independent Films | true | false |
| 7 | 5 | Bride Flight | $125,688 | -31.6% | 94 | -2 | $1,337 | $2,763,769 | 7 | A-Film Distribution | false | false |
| 8 | 6 | Burn After Reading | $106,434 | -18.9% | 44 | -2 | $2,418 | $1,522,402 | 5 | Universal Pictures International (UPI) | false | false |
| 9 | - | The Class | $68,338 | - | 19 | - | $3,596 | $95,473 | 1 | Cinéart | true | false |
| 10 | 8 | The Baader Meinhof Complex | $36,103 | -23.4% | 2,727 | +2,700 | $13 | $112,318 | 2 | A-Film Distribution | false | false |
| 11 | 7 | Anubis en het Pad der 7 Zonden | $35,963 | -51% | 85 | -21 | $423 | $4,412,148 | 8 | Independent Films | false | false |
| 12 | 11 | The Ottoman Republic | $27,948 | -20% | - | - | - | $79,109 | 2 | N/A | false | false |
| 13 | 13 | Friendship | $21,144 | -33.1% | - | - | - | $114,301 | 3 | N/A | false | false |
| 14 | 15 | Blindness | $19,175 | -32.7% | 18 | +1 | $1,065 | $87,747 | 2 | RCV Film Distribution | false | false |
| 15 | 9 | Radeloos | $17,888 | -60.2% | 62 | -20 | $288 | $2,438,334 | 9 | RCV Film Distribution | false | false |
| 16 | 10 | Nights in Rodanthe | $17,532 | -56.7% | 31 | -5 | $565 | $189,215 | 3 | Warner Bros. | false | false |
| 17 | 12 | My Best Friend's Girl | $14,493 | -58.3% | 16 | -23 | $905 | $1,260,910 | 8 | RCV Film Distribution | false | false |
| 18 | 14 | Eagle Eye | $12,922 | -56.4% | 18 | -23 | $717 | $1,878,333 | 8 | Universal Pictures International (UPI) | false | false |
| 19 | 18 | Boy A | $12,214 | -34.2% | 10 | - | $1,221 | $78,719 | 3 | Cinemien | false | false |
| 20 | 17 | Mamma Mia! | $9,475 | -52.9% | 47 | - | $201 | $8,359,070 | 20 | Universal Pictures International (UPI) | false | false |
| 21 | 16 | How to Lose Friends & Alienate People | $9,051 | -67.7% | 14 | -10 | $646 | $145,004 | 3 | RCV Film Distribution | false | false |
| 22 | 19 | Welcome to the Sticks | $8,748 | -48.9% | 13 | -1 | $672 | $421,691 | 12 | Paradiso Entertainment | false | false |
| 23 | - | The Wave | $5,996 | - | 8 | - | $749 | $5,996 | 1 | Paradiso Entertainment | true | false |
| 24 | - | Cargo 200 | $1,147 | - | 3 | - | $382 | $1,147 | 1 | Filmmuseum Distributie | true | false |
