| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Madagascar: Escape 2 Africa | $2,508,220 | - | 152 | - | $16,501 | $2,508,220 | 1 | Universal Pictures International (UPI) | true | false |
| 2 | 1 | Quantum of Solace | $394,803 | -39.3% | 122 | -39 | $3,236 | $9,557,769 | 5 | Walt Disney Pictures | false | false |
| 3 | 12 | Vicky Cristina Barcelona | $198,177 | +1,012.1% | 19 | +14 | $10,430 | $969,337 | 9 | Frenetic Films | false | false |
| 4 | 2 | Body of Lies | $186,299 | -36.2% | 51 | -6 | $3,652 | $863,807 | 3 | Warner Bros. | false | false |
| 5 | - | Four Christmases | $99,170 | - | 24 | - | $4,132 | $99,170 | 1 | Warner Bros. | true | false |
| 6 | 3 | Changeling | $86,432 | -19.5% | 25 | - | $3,457 | $560,420 | 4 | Universal Pictures International (UPI) | false | false |
| 7 | 7 | Welcome to the Sticks | $39,786 | -11.7% | 12 | - | $3,315 | $8,714,303 | 41 | Pathé | false | false |
| 8 | 5 | Gomorrah | $34,861 | -26.9% | 12 | -2 | $2,905 | $993,428 | 15 | Filmcoopi | false | false |
| 9 | 4 | Max Payne | $33,841 | -57.1% | 19 | -13 | $1,781 | $432,277 | 4 | 20th Century Fox International | false | false |
| 10 | 6 | Burn After Reading | $21,149 | -53.2% | 14 | -6 | $1,510 | $1,826,222 | 12 | Ascot Elite Entertainment Group | false | false |
| 11 | 8 | High School Musical 3: Senior Year | $20,601 | -41.1% | 31 | -6 | $664 | $2,027,229 | 7 | Walt Disney Pictures | false | false |
| 12 | - | RocknRolla | $16,628 | - | 6 | - | $2,771 | $16,628 | 1 | Warner Bros. | true | false |
| 13 | 10 | Mamma Mia! | $15,579 | -52.2% | 16 | -13 | $973 | $8,822,268 | 21 | Universal Pictures International (UPI) | false | false |
| 14 | - | The Boy in the Striped Pajamas | $13,154 | - | 7 | - | $1,879 | $39,711 | 2 | Walt Disney Pictures | false | false |
| 15 | - | Home | $12,359 | - | 7 | - | $1,765 | $447,975 | 8 | Filmcoopi | false | false |
| 16 | 11 | North Face | $11,864 | -51.8% | 9 | -15 | $1,318 | $846,227 | 9 | Rialto Distribution | false | false |
| 17 | - | The Duchess | $11,196 | - | 4 | - | $2,799 | $91,922 | 4 | Pathé | false | false |
| 18 | 17 | Fly Me to the Moon 3D | $2,378 | -3.8% | 2 | - | $1,189 | $31,472 | 6 | N/A | false | false |
| 19 | 19 | Eagle Eye | $281 | -86.2% | 1 | -5 | $281 | $1,085,790 | 10 | Universal Pictures International (UPI) | false | false |
| 20 | 18 | Hellboy II: The Golden Army | $271 | -87.8% | 1 | -6 | $271 | $691,077 | 21 | Universal Pictures International (UPI) | false | false |
| 21 | 16 | Kung Fu Panda | $166 | -96.5% | 8 | - | $20 | $5,005,434 | 23 | Universal Pictures International (UPI) | false | false |
