| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Madagascar: Escape 2 Africa | $553,500 | -32.5% | 192 | - | $2,882 | $3,253,267 | 3 | Universal Pictures International (UPI) | false | false |
| 2 | 3 | Winter in Wartime | $524,625 | +24.5% | 95 | - | $5,522 | $1,111,709 | 2 | Benelux Film Distributors | false | false |
| 3 | 2 | Quantum of Solace | $495,348 | -28.3% | 135 | - | $3,669 | $7,266,241 | 5 | Sony Pictures Releasing | false | false |
| 4 | - | Twilight | $255,634 | - | 60 | - | $4,260 | $261,084 | 1 | Independent Films | true | false |
| 5 | 5 | Body of Lies | $128,738 | -39% | 60 | - | $2,145 | $780,039 | 3 | Warner Bros. | false | false |
| 6 | - | A.R.O.G | $113,187 | - | - | - | - | $113,187 | 1 | N/A | true | false |
| 7 | - | Changeling | $107,462 | - | 30 | - | $3,582 | $128,510 | 1 | Universal Pictures International (UPI) | true | false |
| 8 | 6 | The Women | $91,576 | -36.2% | 58 | - | $1,578 | $465,828 | 2 | Independent Films | false | false |
| 9 | 7 | Bride Flight | $84,284 | -32.9% | 86 | -8 | $980 | $2,906,135 | 8 | A-Film Distribution | false | false |
| 10 | 8 | Burn After Reading | $72,127 | -32.2% | 40 | -4 | $1,803 | $1,624,755 | 6 | Universal Pictures International (UPI) | false | false |
| 11 | - | Pride and Glory | $70,793 | - | 30 | - | $2,359 | $97,532 | 1 | RCV Film Distribution | true | false |
| 12 | 9 | The Class | $62,953 | -7.9% | 19 | - | $3,313 | $189,710 | 2 | Cinéart | false | false |
| 13 | 4 | Sinterklaas en het geheim van het grote boek | $46,640 | -79.9% | 98 | -3 | $475 | $2,455,690 | 9 | RCV Film Distribution | false | false |
| 14 | - | Muro: Nalet Olsun Içimdeki Insan Sevgisine | $33,594 | - | - | - | - | $33,594 | 1 | N/A | true | false |
| 15 | 11 | Anubis en het Pad der 7 Zonden | $33,272 | -7.5% | 75 | -10 | $443 | $4,463,068 | 9 | Independent Films | false | false |
| 16 | 10 | The Baader Meinhof Complex | $25,819 | -28.5% | 23 | -2,704 | $1,122 | $152,512 | 3 | A-Film Distribution | false | false |
| 17 | - | Cherry Blossoms | $15,470 | - | 17 | - | $910 | $20,281 | 1 | Cinemien | true | false |
| 18 | 22 | Welcome to the Sticks | $14,268 | +63.1% | 15 | +2 | $951 | $442,788 | 13 | Paradiso Entertainment | false | false |
| 19 | 14 | Blindness | $10,467 | -45.4% | 17 | -1 | $615 | $119,455 | 3 | RCV Film Distribution | false | false |
| 20 | 13 | Friendship | $10,228 | -51.6% | - | - | - | $133,529 | 4 | N/A | false | false |
| 21 | 19 | Boy A | $9,099 | -25.5% | 10 | - | $909 | $100,621 | 4 | Cinemien | false | false |
| 22 | 15 | Radeloos | $8,562 | -52.1% | 41 | -21 | $208 | $2,587,354 | 10 | RCV Film Distribution | false | false |
| 23 | 20 | Mamma Mia! | $8,163 | -13.8% | 49 | +2 | $166 | $9,743,100 | 21 | Universal Pictures International (UPI) | false | false |
| 24 | - | Jagdhunde | $1,129 | - | 3 | - | $376 | $1,129 | 1 | Filmmuseum Distributie | true | false |
