| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Madagascar: Escape 2 Africa | $729,504 | -55.9% | 155 | -1 | $4,706 | $2,693,529 | 2 | Paramount Pictures International | false | false |
| 2 | 2 | High School Musical 3: Senior Year | $99,457 | -54.8% | 124 | +36 | $802 | $960,395 | 3 | Walt Disney Pictures | false | false |
| 3 | 3 | Body of Lies | $82,554 | -45.8% | 47 | +1 | $1,756 | $551,744 | 3 | Warner Bros. | false | false |
| 4 | - | The Duchess | $55,698 | - | 15 | - | $3,713 | $55,698 | 1 | United International Pictures | true | false |
| 5 | 4 | Quarantine | $50,345 | -49.5% | 30 | - | $1,678 | $166,309 | 2 | Sony Pictures Releasing | false | false |
| 6 | 5 | Righteous Kill | $34,108 | -50.4% | 44 | +4 | $775 | $450,192 | 4 | CDI Films | false | false |
| 7 | - | Planet Terror | $27,351 | - | 24 | - | $1,139 | $27,351 | 1 | Pachamama Cine | true | false |
| 8 | 6 | Death Sentence | $23,366 | -61.5% | 36 | +5 | $649 | $93,513 | 2 | Distribution Company | false | false |
| 9 | - | RocknRolla | $21,703 | - | 13 | - | $1,669 | $21,703 | 1 | Warner Bros. | true | false |
| 10 | - | Deception | $21,165 | - | 13 | - | $1,628 | $21,165 | 1 | Alfa Films | true | false |
| 11 | 7 | Quantum of Solace | $19,400 | -62% | 22 | -21 | $881 | $1,165,350 | 6 | Sony Pictures Releasing | false | false |
| 12 | 8 | Che: Part One | $18,944 | -60.6% | 34 | -10 | $557 | $570,597 | 5 | Alfa Films | false | false |
| 13 | 18 | Death Defying Acts | $17,867 | +100.9% | 18 | +5 | $992 | $100,036 | 3 | Alfa Films | false | false |
| 14 | 10 | Saw V | $14,154 | -51.7% | 33 | -6 | $428 | $1,004,619 | 7 | Walt Disney Pictures | false | false |
| 15 | - | Ira & Abby | $13,733 | - | 10 | - | $1,373 | $13,733 | 1 | CDI Films | true | false |
| 16 | 11 | Elegy | $12,406 | -40% | 20 | -2 | $620 | $143,887 | 4 | Distribution Company | false | false |
| 17 | 12 | Max Payne | $10,580 | -43.9% | 31 | +10 | $341 | $148,156 | 4 | 20th Century Fox International | false | false |
| 18 | 24 | My Mom's New Boyfriend | $10,191 | +204.6% | 20 | +15 | $509 | $114,585 | 5 | - | false | false |
| 19 | 9 | The Boy in the Striped Pajamas | $8,808 | -72.8% | 12 | -1 | $734 | $48,150 | 2 | Walt Disney Pictures | false | false |
| 20 | 14 | The Bank Job | $8,244 | -47.8% | 23 | -3 | $358 | $593,231 | 9 | Alfa Films | false | false |
| 21 | 13 | Flawless | $7,963 | -53.6% | 24 | +2 | $331 | $220,700 | 6 | Distribution Company | false | false |
| 22 | 16 | Beverly Hills Chihuahua | $7,873 | -38.6% | 32 | -22 | $246 | $1,499,338 | 10 | Walt Disney Pictures | false | false |
| 23 | 15 | Late Bloomers | $7,762 | -43.9% | 4 | - | $1,940 | $38,789 | 3 | Primer Plano Film Group | false | false |
| 24 | 22 | Journey to the Center of the Earth | $5,692 | +38.2% | 2 | +1 | $2,846 | $1,314,003 | 22 | Distribution Company | false | false |
| 25 | - | La leyenda | $5,258 | - | 24 | - | $219 | $194,795 | 4 | United International Pictures | false | false |
| 26 | 19 | Red Like the Sky 2008 Re-release | $4,222 | -42.1% | 3 | -1 | $1,407 | $12,769 | 2 | Primer Plano Film Group | false | false |
| 27 | 28 | The Nightmare Before Christmas 2009 3D Release | $3,422 | +150.3% | 2 | +1 | $1,711 | $207,899 | 7 | Walt Disney Pictures | false | false |
| 28 | 17 | Burn After Reading | $3,388 | -68.6% | 11 | -6 | $308 | $845,121 | 8 | United International Pictures | false | false |
| 29 | - | Madagascar | $3,105 | - | 3 | - | $1,035 | $4,933,447 | 180 | United International Pictures | false | false |
| 30 | 21 | Fados | $3,072 | -51.7% | 3 | -1 | $1,024 | $23,879 | 3 | Distribution Company | false | false |
| 31 | 23 | Tear This Heart Out | $2,234 | -43.4% | 7 | - | $319 | $25,761 | 3 | 20th Century Fox International | false | false |
| 32 | 20 | Black Christmas | $2,119 | -70% | 7 | -10 | $302 | $89,723 | 5 | Distribution Company | false | false |
| 33 | 25 | Manual of Love 2008 Re-release | $1,701 | -37.2% | 3 | -2 | $567 | $127,847 | 12 | Notro Films | false | false |
| 34 | - | Furtivo | $1,428 | - | 3 | - | $476 | $1,428 | 1 | Notro Films | true | false |
| 35 | 27 | Aniceto | $1,346 | -30.5% | 2 | -1 | $673 | $123,139 | 27 | Primer Plano Film Group | false | false |
| 36 | - | Mirrors | $941 | - | 7 | - | $134 | $612,930 | 11 | 20th Century Fox International | false | false |
| 37 | - | Nights in Rodanthe | $671 | - | 6 | - | $111 | $885,885 | 11 | Warner Bros. | false | false |
| 38 | 29 | Shara | $586 | -24.5% | 3 | +1 | $195 | $43,271 | 7 | Zeta Films | false | false |
| 39 | 43 | Don't Look Down | $501 | +902% | 1 | - | $501 | $17,773 | 7 | Primer Plano Film Group | false | false |
| 40 | - | Blindness | $458 | - | 4 | - | $114 | $177,728 | 7 | 20th Century Fox International | false | false |
| 41 | 31 | The Women | $420 | -26.3% | 2 | - | $210 | $128,103 | 7 | CDI Films | false | false |
| 42 | - | Camera Obscura 2008 Re-release | $231 | - | 1 | - | $231 | $63,790 | 9 | Distribution Company | false | false |
| 43 | 41 | Days of Darkness | $212 | +103.8% | 2 | +1 | $106 | $14,893 | 9 | Alfa Films | false | false |
| 44 | 34 | You Don't Mess with the Zohan | $146 | -54.5% | 2 | -1 | $73 | $653,687 | 13 | Sony Pictures Releasing | false | false |
| 45 | 32 | The Paranoids | $138 | -68.3% | 1 | - | $138 | $40,488 | 8 | Primer Plano Film Group | false | false |
| 46 | 38 | The Magic Flute | $134 | -10.7% | 1 | - | $134 | $24,182 | 8 | Distribution Company | false | false |
| 47 | - | Kung Fu Panda | $129 | - | 1 | - | $129 | $5,038,274 | 24 | United International Pictures | false | false |
| 48 | - | Fast Food Nation | $118 | - | 1 | - | $118 | $41,608 | 8 | Impacto Cine | false | false |
| 49 | 33 | Four Minutes | $111 | -71.3% | 1 | - | $111 | $158,726 | 16 | Alfa Films | false | false |
| 50 | 46 | Hellboy II: The Golden Army | $107 | +205.7% | 1 | - | $107 | $298,988 | 10 | United International Pictures | false | false |
| 51 | 35 | My Brother is an Only Child | $94 | -64.9% | 1 | - | $94 | $223,627 | 13 | Alfa Films | false | false |
| 52 | 39 | Mamma Mia! | $70 | -47.4% | 1 | - | $70 | $1,463,325 | 17 | United International Pictures | false | false |
| 53 | - | Appaloosa | $51 | - | 1 | - | $51 | $339,178 | 10 | Distribution Company | false | false |
| 54 | - | Taken | $38 | - | 1 | - | $38 | $521,001 | 13 | 20th Century Fox International | false | false |
| 55 | - | 100% lucha, la película | $7 | - | 1 | - | $7 | $874,285 | 23 | Primer Plano Film Group | false | false |
| 56 | - | El cine de Maite | $6 | - | 1 | - | $6 | $4,155 | 9 | Primer Plano Film Group | false | false |
