| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Madagascar: Escape 2 Africa | $113,097 | - | 9 | - | $12,566 | $113,097 | 1 | Universal Pictures International (UPI) | true | false |
| 2 | - | The Day the Earth Stood Still | $35,704 | - | 4 | - | $8,926 | $35,704 | 1 | Universal Pictures International (UPI) | true | false |
| 3 | 1 | Transporter 3 | $14,284 | -67.7% | 3 | - | $4,761 | $69,591 | 2 | ACME | false | false |
| 4 | - | Sex Drive | $9,202 | - | 2 | - | $4,601 | $9,202 | 1 | ACME | true | false |
| 5 | 2 | Vicky Cristina Barcelona | $8,539 | -32.9% | 2 | - | $4,269 | $125,557 | 5 | ACME | false | false |
| 6 | 3 | Twilight | $7,523 | -32.5% | 2 | - | $3,761 | $49,279 | 3 | ACME | false | false |
| 7 | 5 | Quantum of Solace | $5,032 | -43.3% | 6 | - | $838 | $385,814 | 6 | Universal Pictures International (UPI) | false | false |
| 8 | 4 | Quarantine | $5,022 | -50.9% | 3 | - | $1,674 | $20,502 | 2 | Universal Pictures International (UPI) | false | false |
| 9 | 8 | Body of Lies | $4,803 | -29.4% | 3 | - | $1,601 | $35,917 | 3 | Universal Pictures International (UPI) | false | false |
| 10 | 7 | My Best Friend's Girl | $4,086 | -42.3% | 2 | - | $2,043 | $108,241 | 6 | ACME | false | false |
| 11 | 9 | Fly Me to the Moon 3D | $3,037 | -39.3% | 1 | - | $3,037 | $66,433 | 5 | Universal Pictures International (UPI) | false | false |
| 12 | 6 | Journey to the Center of the Earth | $2,948 | -61.5% | 1 | - | $2,948 | $542,152 | 12 | Universal Pictures International (UPI) | false | false |
| 13 | 11 | The Ghost | $2,555 | -44.9% | 2 | - | $1,277 | $33,552 | 4 | ACME | false | false |
| 14 | 12 | Admiral | $2,002 | -45.9% | 3 | - | $667 | $98,918 | 6 | ACME | false | false |
| 15 | 14 | U2 3D | $1,524 | -47.2% | 1 | - | $1,524 | $37,425 | 5 | Universal Pictures International (UPI) | false | false |
