| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Madagascar: Escape 2 Africa | $1,899,031 | -38.8% | 501 | -77 | $3,790 | $8,070,003 | 2 | Paramount Pictures International | false | false |
| 2 | - | Twilight | $1,439,320 | - | 321 | - | $4,483 | $1,580,538 | 1 | Paris Filmes | true | false |
| 3 | 2 | Burn After Reading | $161,611 | -33.7% | 101 | -2 | $1,600 | $1,690,451 | 4 | Universal Pictures International (UPI) | false | false |
| 4 | 4 | Body of Lies | $128,242 | -34.1% | 101 | +1 | $1,269 | $1,447,649 | 4 | Warner Bros. | false | false |
| 5 | 3 | Transporter 3 | $126,948 | -44% | 100 | - | $1,269 | $501,883 | 2 | Imagem Filmes | false | false |
| 6 | 5 | Vicky Cristina Barcelona | $68,153 | -36.8% | 77 | -3 | $885 | $2,120,459 | 6 | Imagem Filmes | false | false |
| 7 | - | Gomorrah | $54,649 | - | 32 | - | $1,707 | $62,679 | 1 | Paris Filmes | true | false |
| 8 | 9 | The Boy in the Striped Pajamas | $44,658 | -36.9% | 20 | - | $2,232 | $147,406 | 2 | Walt Disney Pictures | false | false |
| 9 | 7 | Between the Sheets | $41,928 | -50.9% | 96 | -16 | $436 | $433,397 | 3 | Imagem Filmes | false | false |
| 10 | 6 | Quantum of Solace | $28,829 | -69.8% | 100 | -100 | $288 | $7,318,636 | 7 | Sony Pictures Releasing | false | false |
| 11 | 10 | High School Musical 3: Senior Year | $26,030 | -51.7% | 164 | -39 | $158 | $5,439,130 | 9 | Walt Disney Pictures | false | false |
| 12 | 8 | College | $23,179 | -72.7% | 73 | -59 | $317 | $523,811 | 3 | California Filmes | false | false |
| 13 | 11 | Max Payne | $23,098 | -50.4% | 80 | -19 | $288 | $989,378 | 5 | 20th Century Fox International | false | false |
| 14 | 16 | Be Kind Rewind | $19,804 | -32.3% | 10 | - | $1,980 | $77,675 | 2 | Europa Filmes | false | false |
| 15 | 14 | Once Upon a Time in Rio | $18,466 | -48.6% | 38 | -9 | $485 | $461,490 | 5 | Walt Disney Pictures | false | false |
| 16 | 15 | Romance | $17,750 | -48.3% | 56 | -10 | $316 | $827,360 | 6 | Walt Disney Pictures | false | false |
| 17 | 18 | Dan in Real Life | $14,888 | -37.6% | 37 | -1 | $402 | $802,529 | 8 | Europa Filmes | false | false |
| 18 | 12 | The Strangers | $14,456 | -65.6% | 53 | -19 | $272 | $987,512 | 5 | Paris Filmes | false | false |
| 19 | 17 | The Duchess | $11,554 | -55.5% | 28 | -4 | $412 | $421,309 | 5 | Paramount Pictures International | false | false |
| 20 | 22 | Traitor | $7,052 | -26.4% | 19 | -4 | $371 | $213,071 | 6 | PlayArte Pictures | false | false |
| 21 | 19 | Saw V | $6,316 | -54.5% | 41 | -32 | $154 | $2,412,716 | 8 | Walt Disney Pictures | false | false |
| 22 | 21 | Blindness | $5,541 | -47.7% | 26 | -9 | $213 | $3,275,342 | 15 | 20th Century Fox International | false | false |
| 23 | 20 | Last Stop 174 | $5,273 | -52.9% | 35 | -17 | $150 | $1,574,933 | 9 | Paramount Pictures International | false | false |
| 24 | 13 | Deception | $4,394 | -88.4% | 17 | -20 | $258 | $206,559 | 3 | Paris Filmes | false | false |
| 25 | 32 | December | $3,557 | +19.1% | 10 | +1 | $355 | $66,637 | 5 | Europa Filmes | false | false |
| 26 | 23 | Appaloosa | $2,867 | -56.3% | 3 | -3 | $955 | $30,291 | 3 | PlayArte Pictures | false | false |
| 27 | 30 | Fly Me to the Moon 3D | $2,048 | -37.9% | 21 | -16 | $97 | $1,601,725 | 11 | PlayArte Pictures | false | false |
| 28 | 37 | The House Bunny | $1,888 | -11.7% | 5 | +1 | $377 | $317,987 | 11 | Sony Pictures Releasing | false | false |
| 29 | 36 | Disaster Movie | $1,583 | -27.3% | 9 | -3 | $175 | $2,906,463 | 12 | Imagem Filmes | false | false |
| 30 | 33 | Mamma Mia! | $1,248 | -56.6% | 7 | -6 | $178 | $2,980,656 | 15 | Paramount Pictures International | false | false |
| 31 | 43 | Step Brothers | $1,212 | -21.6% | 10 | -2 | $121 | $215,623 | 9 | Sony Pictures Releasing | false | false |
| 32 | 35 | A Guerra dos Rocha | $1,180 | -46.6% | 10 | -4 | $118 | $1,003,833 | 11 | 20th Century Fox International | false | false |
| 33 | 38 | Death Race | $1,046 | -49.7% | 8 | -6 | $130 | $518,275 | 10 | Paramount Pictures International | false | false |
| 34 | 53 | Leonera | $766 | +12.8% | 3 | - | $255 | $30,531 | 7 | Walt Disney Pictures | false | false |
| 35 | 24 | Scar | $745 | -87.1% | 2 | -9 | $372 | $129,576 | 5 | PlayArte Pictures | false | false |
| 36 | 52 | Linha de Passe | $642 | -6% | 4 | +1 | $160 | $610,665 | 16 | Paramount Pictures International | false | false |
| 37 | 54 | When Did You Last See Your Father? | $178 | -73.1% | 2 | - | $89 | $8,534 | 3 | Sony Pictures Releasing | false | false |
| 38 | - | Nights in Rodanthe | $145 | - | 2 | - | $72 | $1,318,500 | 12 | Warner Bros. | false | false |
| 39 | 48 | RocknRolla | $103 | -87.6% | 1 | -4 | $103 | $241,242 | 8 | Warner Bros. | false | false |
| 40 | 75 | Once Upon a Time... | $53 | - | 1 | - | $53 | $2,814,071 | 22 | Sony Pictures Releasing | false | false |
