| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Madagascar: Escape 2 Africa | $1,309,273 | -12.3% | 147 | +8 | $8,906 | $6,310,004 | 3 | Universal Pictures International (UPI) | false | false |
| 2 | 2 | The Day the Earth Stood Still | $188,776 | -42.5% | 60 | -3 | $3,146 | $591,014 | 2 | 20th Century Fox International | false | false |
| 3 | 3 | Quantum of Solace | $166,492 | -25.9% | 67 | -24 | $2,484 | $10,060,815 | 7 | Walt Disney Pictures | false | false |
| 4 | 4 | Vicky Cristina Barcelona | $149,040 | -14% | 20 | -4 | $7,452 | $1,443,416 | 11 | Frenetic Films | false | false |
| 5 | 5 | Burn After Reading | $123,423 | -26.3% | 19 | -7 | $6,495 | $2,205,327 | 14 | Ascot Elite Entertainment Group | false | false |
| 6 | - | 1½ Knights - In Search of the Ravishing Princess Herzelinde | $119,878 | - | 31 | - | $3,867 | $119,878 | 1 | Warner Bros. | true | false |
| 7 | - | The Heir Apparent: Largo Winch | $73,283 | - | 14 | - | $5,234 | $81,504 | 1 | Frenetic Films | true | false |
| 8 | 6 | Four Christmases | $69,513 | -14.9% | 24 | - | $2,896 | $301,936 | 3 | Warner Bros. | false | false |
| 9 | 7 | Body of Lies | $65,880 | +20.8% | 25 | +7 | $2,635 | $1,081,303 | 5 | Warner Bros. | false | false |
| 10 | - | Natale a Rio | $64,784 | - | 13 | - | $4,983 | $64,784 | 1 | - | true | false |
| 11 | - | Wild Child | $56,217 | - | 34 | - | $1,653 | $56,217 | 1 | Universal Pictures International (UPI) | true | false |
| 12 | 8 | Inkheart | $45,542 | -10.4% | 24 | -4 | $1,897 | $96,373 | 2 | Warner Bros. | false | false |
| 13 | 9 | Changeling | $40,140 | -18.8% | 24 | - | $1,672 | $673,705 | 6 | Universal Pictures International (UPI) | false | false |
| 14 | 10 | Welcome to the Sticks | $37,107 | +6.3% | 10 | - | $3,710 | $8,798,103 | 43 | Pathé | false | false |
| 15 | 11 | Gomorrah | $28,030 | -12.8% | 9 | -2 | $3,114 | $1,083,729 | 17 | Filmcoopi | false | false |
| 16 | - | The Crimson Wing: Mystery of the Flamingos | $13,549 | - | 15 | - | $903 | $14,495 | 1 | Walt Disney Pictures | true | false |
| 17 | 15 | Mamma Mia! | $8,617 | +20.7% | 13 | -3 | $662 | $8,841,117 | 23 | Universal Pictures International (UPI) | false | false |
