| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Yes Man | $700,588 | -15.8% | 88 | - | $7,961 | $1,752,700 | 2 | Warner Bros. | false | false |
| 2 | 2 | Winter in Wartime | $432,627 | +7.9% | 100 | -1 | $4,326 | $6,523,586 | 8 | Benelux Film Distributors | false | false |
| 3 | 3 | Australia | $382,631 | +10.4% | 104 | +2 | $3,679 | $3,140,405 | 5 | Warner Bros. | false | false |
| 4 | - | Seven Pounds | $269,359 | - | 41 | - | $6,569 | $274,082 | 1 | Sony Pictures Releasing | true | false |
| 5 | 5 | Madagascar: Escape 2 Africa | $207,558 | +57.1% | 133 | -17 | $1,560 | $7,807,546 | 9 | Universal Pictures International (UPI) | false | false |
| 6 | 4 | The Silent Army | $178,001 | -5.3% | 89 | -2 | $2,000 | $2,477,126 | 6 | Independent Films | false | false |
| 7 | 9 | High School Musical 3: Senior Year | $109,214 | +23.5% | 107 | -6 | $1,020 | $2,544,871 | 6 | Walt Disney Pictures | false | false |
| 8 | 7 | Righteous Kill | $97,025 | -20.3% | 30 | - | $3,234 | $288,915 | 2 | Moonlight Films | false | false |
| 9 | 8 | Bedtime Stories | $91,569 | -18.1% | 60 | - | $1,526 | $1,239,798 | 4 | Walt Disney Pictures | false | false |
| 10 | 10 | Vicky Cristina Barcelona | $84,031 | +4.7% | 21 | -2 | $4,001 | $852,700 | 6 | Cinéart | false | false |
| 11 | 6 | Saw V | $80,597 | -38.8% | 58 | - | $1,389 | $393,171 | 2 | Benelux Film Distributors | false | false |
| 12 | - | Frost/Nixon | $64,771 | - | 29 | - | $2,233 | $67,703 | 1 | Universal Pictures International (UPI) | true | false |
| 13 | 13 | The Boy in the Striped Pajamas | $57,367 | +3.9% | 28 | +1 | $2,048 | $142,479 | 2 | Walt Disney Pictures | false | false |
| 14 | - | CC2C | $45,682 | - | 6 | - | $7,613 | $45,682 | 1 | Warner Bros. | true | false |
| 15 | 12 | Quantum of Solace | $44,658 | -23.6% | 45 | -12 | $992 | $9,251,862 | 11 | Sony Pictures Releasing | false | false |
| 16 | - | Mesrine: Killer Instinct | $43,926 | - | 30 | - | $1,464 | $87,252 | 1 | A-Film Distribution | true | false |
| 17 | 14 | Twilight | $39,639 | -12.8% | 33 | -7 | $1,201 | $1,215,557 | 7 | Independent Films | false | false |
| 18 | 16 | The Class | $31,751 | +21.7% | 19 | - | $1,671 | $567,328 | 8 | Cinéart | false | false |
| 19 | - | Piet Piraat en het zwaard van Zilvertand | $30,300 | - | 74 | - | $409 | $438,147 | 5 | Independent Films | false | false |
| 20 | 11 | The Day the Earth Stood Still | $26,836 | -61.5% | 38 | -36 | $706 | $2,188,225 | 6 | Warner Bros. | false | false |
| 21 | 19 | The Visitor | $26,617 | +41.3% | 8 | - | $3,327 | $65,999 | 2 | Wild Bunch Distribution | false | false |
| 22 | 15 | Changeling | $22,222 | -30.9% | 22 | -6 | $1,010 | $680,369 | 7 | Universal Pictures International (UPI) | false | false |
| 23 | - | Incendiary | $17,900 | - | 15 | - | $1,193 | $17,900 | 1 | RCV Film Distribution | true | false |
| 24 | - | A Woman in Berlin | $13,289 | - | 14 | - | $949 | $13,289 | 1 | A-Film Distribution | true | false |
| 25 | - | Hamlet 2 | $10,066 | - | 10 | - | $1,006 | $10,066 | 1 | A-Film Distribution | true | false |
| 26 | - | Youssou Ndour: I Bring What I Love | $4,378 | - | 6 | - | $729 | $4,378 | 1 | Cinemien | true | false |
| 27 | - | 12 | $3,279 | - | 3 | - | $1,093 | $3,279 | 1 | Filmmuseum Distributie | true | false |
