| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Curious Case of Benjamin Button | $389,986 | - | 33 | - | $11,817 | $389,986 | 1 | Warner Bros. | true | false |
| 2 | - | Underworld: Rise of the Lycans | $315,456 | - | 26 | - | $12,132 | $435,474 | 1 | N/A | true | false |
| 3 | 2 | Bride Wars | $127,785 | -52% | 27 | - | $4,732 | $703,191 | 2 | N/A | false | false |
| 4 | 1 | The Wedding Game | $116,395 | -58.6% | 26 | -11 | $4,476 | $1,000,065 | 3 | N/A | false | false |
| 5 | 3 | Love Matters | $99,175 | -60% | 25 | -11 | $3,967 | $1,010,690 | 3 | N/A | false | false |
| 6 | - | Defiance | $62,624 | - | 11 | - | $5,693 | $79,205 | 1 | N/A | true | false |
| 7 | 4 | Inkheart | $56,874 | -73.4% | 26 | -4 | $2,187 | $910,703 | 3 | N/A | false | false |
| 8 | 6 | Red Cliff II | $48,254 | -55.5% | 17 | -7 | $2,838 | $2,055,917 | 5 | N/A | false | false |
| 9 | 5 | All's Well, Ends Well 2009 | $28,662 | -83.5% | 8 | -11 | $3,582 | $525,290 | 3 | N/A | false | false |
| 10 | 9 | The Reader | $27,276 | -13.6% | 4 | +1 | $6,819 | $108,735 | 3 | Golden Village Pictures | false | false |
| 11 | - | Look for a Star | $23,851 | - | 21 | - | $1,135 | $23,851 | - | N/A | - | false |
| 12 | 8 | Doubt | $16,455 | -51.8% | 4 | - | $4,113 | $67,843 | 2 | N/A | false | false |
| 13 | 10 | Changeling | $9,491 | -69.2% | 5 | -2 | $1,898 | $265,379 | 4 | N/A | false | false |
| 14 | - | The Wrestler | $5,669 | - | 1 | - | $5,669 | $9,479 | - | Cathay-Keris Films | - | false |
| 15 | 14 | Milk | $4,247 | -44.8% | 2 | - | $2,123 | $86,651 | 5 | N/A | false | false |
| 16 | 17 | Rachel Getting Married | $1,424 | -61.9% | 2 | -1 | $712 | $67,683 | 5 | N/A | false | false |
| 17 | 13 | CC2C | $1,388 | -84.6% | 2 | -3 | $694 | $144,899 | 4 | N/A | false | false |
| 18 | 19 | Elegy | $1,330 | -57.7% | 1 | - | $1,330 | $38,531 | 6 | N/A | false | false |
| 19 | 20 | Twilight | $1,144 | -56.2% | 1 | - | $1,144 | $1,774,300 | 8 | N/A | false | false |
| 20 | 23 | Bedtime Stories | $531 | -23.7% | 1 | - | $531 | $1,534,899 | 7 | N/A | false | false |
| 21 | 7 | Punisher: War Zone | $247 | -99.3% | 1 | -16 | $247 | $164,685 | 3 | N/A | false | false |
