| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Slumdog Millionaire | $30,859 | +72% | 1 | -5 | $30,859 | $64,024 | 2 | N/A | false | false |
| 2 | 2 | The Pink Panther 2 | $21,624 | +63.7% | 10 | - | $2,162 | $46,936 | 2 | Sony Pictures Releasing | false | false |
| 3 | 3 | The Curious Case of Benjamin Button | $15,258 | +48.9% | 7 | - | $2,179 | $157,731 | 5 | N/A | false | false |
| 4 | 6 | Bedtime Stories | $12,848 | +70.2% | 6 | -1 | $2,141 | $99,215 | 4 | N/A | false | false |
| 5 | 4 | Vicky Cristina Barcelona | $9,986 | +5.5% | 7 | - | $1,426 | $183,852 | 4 | N/A | false | false |
| 6 | 5 | Marley & Me | $9,661 | +17.8% | 4 | -1 | $2,415 | $74,922 | 3 | N/A | false | false |
| 7 | - | The Tale of Despereaux | $7,112 | - | 6 | - | $1,185 | $7,112 | 1 | N/A | true | false |
| 8 | - | The Wrestler | $6,966 | - | 3 | - | $2,322 | $6,966 | 1 | N/A | true | false |
| 9 | 7 | Yes Man | $5,118 | -11.3% | 3 | -1 | $1,706 | $138,181 | 6 | N/A | false | false |
| 10 | 12 | Valkyrie | $3,887 | +27.6% | 3 | - | $1,295 | $80,585 | 5 | N/A | false | false |
| 11 | 8 | U2 3D | $3,762 | -16% | 1 | - | $3,762 | $24,872 | 3 | N/A | false | false |
| 12 | 14 | Bolt | $3,404 | +94.6% | 4 | - | $851 | $148,225 | 8 | N/A | false | false |
| 13 | 10 | Milk | $3,375 | +6.3% | 5 | - | $675 | $24,597 | 3 | N/A | false | false |
| 14 | 11 | In Bruges | $3,123 | +1.7% | 2 | -1 | $1,561 | $18,462 | 3 | N/A | false | false |
| 15 | 9 | Changeling | $2,683 | -25.8% | 3 | -2 | $894 | $117,207 | 6 | N/A | false | false |
| 16 | 15 | Frost/Nixon | $2,577 | +57% | 3 | - | $859 | $6,123 | 2 | N/A | false | false |
| 17 | - | Max Payne | $1,965 | - | 3 | - | $655 | $1,965 | - | N/A | - | false |
| 18 | 19 | Doubt | $1,815 | +92.3% | 2 | - | $907 | $40,256 | 6 | N/A | false | false |
| 19 | 18 | Madagascar: Escape 2 Africa | $1,767 | +60.1% | 3 | - | $589 | $274,921 | 12 | Paramount Pictures International | false | false |
| 20 | 17 | Revolutionary Road | $1,351 | -4.8% | 1 | -1 | $1,351 | $38,842 | 4 | N/A | false | false |
| 21 | 16 | Che: Part One | $1,109 | -22% | 2 | -2 | $554 | $28,316 | 5 | N/A | false | false |
| 22 | 13 | Twilight | $1,090 | -47.9% | 3 | - | $363 | $105,445 | 8 | N/A | false | false |
| 23 | - | Tonky y Otros Amigos | $1,002 | - | 3 | - | $334 | $1,002 | 1 | N/A | true | false |
| 24 | 20 | The Bank Job | $602 | +21.9% | 2 | +1 | $301 | $41,380 | 7 | N/A | false | false |
| 25 | 21 | My Brother is an Only Child | $317 | -0.3% | 1 | - | $317 | $16,635 | 12 | N/A | false | false |
| 26 | 22 | Frozen River | $206 | +28.8% | 1 | - | $206 | $1,900 | 3 | N/A | false | false |
| 27 | 24 | Space Chimps | $117 | -16.4% | 2 | - | $58 | $2,782 | 4 | N/A | false | false |
