| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Bedtime Stories | $187,984 | +3.2% | 32 | - | $5,874 | $463,714 | 2 | Walt Disney Pictures | false | false |
| 2 | 3 | Slumdog Millionaire | $100,231 | +61.8% | 19 | - | $5,275 | $211,630 | 2 | Bazuca Films | false | false |
| 3 | 2 | Valkyrie | $84,369 | -24.5% | 42 | -1 | $2,008 | $529,426 | 3 | 20th Century Fox International | false | false |
| 4 | 4 | The Curious Case of Benjamin Button | $51,322 | -13.4% | 31 | -2 | $1,655 | $908,254 | 6 | Warner Bros. | false | false |
| 5 | - | Doubt | $26,479 | - | 6 | - | $4,413 | $28,313 | 1 | Walt Disney Pictures | true | false |
| 6 | 8 | Coraline | $26,442 | +8.5% | 18 | -4 | $1,469 | $184,113 | 4 | United International Pictures | false | false |
| 7 | 5 | Friday the 13th | $25,829 | -6.7% | 17 | -4 | $1,519 | $157,919 | 3 | United International Pictures | false | false |
| 8 | 6 | He's Just Not That Into You | $20,254 | -20.8% | 3 | -16 | $6,751 | $140,867 | 3 | Warner Bros. | false | false |
| 9 | 7 | Seven Pounds | $18,373 | -27.1% | 15 | - | $1,224 | $55,489 | 2 | Sony Pictures Releasing | false | false |
| 10 | - | The Bank Job | $17,189 | - | 12 | - | $1,432 | $17,189 | 1 | Transeuropa | true | false |
| 11 | 10 | Bolt | $15,708 | -19.2% | 16 | -7 | $981 | $1,637,369 | 10 | Walt Disney Pictures | false | false |
| 12 | 9 | Inkheart | $14,699 | -35.8% | 19 | -12 | $773 | $322,022 | 4 | Warner Bros. | false | false |
| 13 | - | Flawless | $11,445 | - | 10 | - | $1,144 | $11,445 | 1 | Bazuca Films | true | false |
| 14 | - | Rudo y Cursi | $11,380 | - | 31 | - | $367 | $11,380 | 1 | United International Pictures | true | false |
| 15 | 11 | The Duchess | $10,801 | -39.7% | 9 | -2 | $1,200 | $36,814 | 2 | United International Pictures | false | false |
| 16 | 14 | Hotel for Dogs | $9,573 | +6.1% | 7 | -7 | $1,367 | $215,332 | 6 | United International Pictures | false | false |
| 17 | 12 | Yes Man | $9,078 | -39.2% | 6 | -11 | $1,513 | $835,973 | 7 | Warner Bros. | false | false |
| 18 | 13 | Twilight | $8,862 | -14.6% | 14 | +1 | $633 | $1,240,197 | 9 | Bazuca Films | false | false |
| 19 | 28 | The Strangers | $5,141 | +648.3% | 4 | +3 | $1,285 | $86,186 | 6 | Bazuca Films | false | false |
| 20 | 19 | Quarantine | $5,088 | -9.2% | 6 | -5 | $848 | $183,926 | 5 | Sony Pictures Releasing | false | false |
| 21 | - | The Bottle | $3,951 | - | 7 | - | $564 | $3,951 | 1 | - | true | false |
| 22 | 24 | The Tale of Despereaux | $3,204 | +82.5% | 10 | +4 | $320 | $141,477 | 5 | United International Pictures | false | false |
| 23 | 22 | Beverly Hills Chihuahua | $2,986 | -20.6% | 5 | -2 | $597 | $533,240 | 8 | Walt Disney Pictures | false | false |
| 24 | 15 | The Women | $2,790 | -61.9% | 8 | -5 | $348 | $14,450 | 2 | CDI Films | false | false |
| 25 | 18 | Che: Part One | $2,758 | -54.6% | 1 | -2 | $2,758 | $110,118 | 5 | Bazuca Films | false | false |
| 26 | 17 | The Boy in the Striped Pajamas | $2,170 | -67.4% | 4 | -5 | $542 | $224,884 | 7 | Walt Disney Pictures | false | false |
| 27 | 20 | Family Hero | $1,440 | -70.8% | 1 | -2 | $1,440 | $19,948 | 3 | Andes Films | false | false |
| 28 | 16 | Revolutionary Road | $1,334 | -80.2% | 2 | -6 | $667 | $124,733 | 5 | United International Pictures | false | false |
| 29 | 25 | Bride Wars | $313 | -81.2% | 1 | -5 | $313 | $134,293 | 5 | 20th Century Fox International | false | false |
| 30 | 23 | The Pink Panther 2 | $294 | -85.5% | 2 | -5 | $147 | $76,184 | 4 | Sony Pictures Releasing | false | false |
| 31 | - | Irma Vap: O Retorno | $235 | - | 1 | - | $235 | $77,262 | 16 | Bazuca Films | false | false |
| 32 | - | Marley & Me | $228 | - | 1 | - | $228 | $167,017 | 7 | 20th Century Fox International | false | false |
| 33 | 27 | The Forbidden Kingdom | $192 | -74.5% | 1 | -3 | $192 | $45,675 | 4 | Andes Films | false | false |
