| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Slumdog Millionaire | $23,739 | -19.5% | 6 | - | $3,956 | $168,380 | 4 | N/A | false | false |
| 2 | - | Stranded | $17,918 | - | 6 | - | $2,986 | $17,918 | 1 | N/A | true | false |
| 3 | 2 | Seven Pounds | $11,570 | -21.5% | 6 | - | $1,928 | $33,607 | 2 | N/A | false | false |
| 4 | - | Bride Wars | $11,224 | - | 6 | - | $1,870 | $32,076 | 1 | 20th Century Fox International | true | false |
| 5 | 4 | The Pink Panther 2 | $6,976 | +0.7% | 10 | +5 | $697 | $82,893 | 4 | Sony Pictures Releasing | false | false |
| 6 | 3 | The Curious Case of Benjamin Button | $5,700 | -17.7% | 5 | - | $1,140 | $180,629 | 7 | N/A | false | false |
| 7 | 6 | Vicky Cristina Barcelona | $4,766 | -8.6% | 3 | -4 | $1,588 | $197,296 | 6 | N/A | false | false |
| 8 | 5 | Bedtime Stories | $3,994 | -33.9% | 5 | -1 | $798 | $116,406 | 6 | N/A | false | false |
| 9 | - | Wild Child | $3,757 | - | 5 | - | $751 | $3,757 | 1 | N/A | true | false |
| 10 | 7 | Milk | $3,470 | -29.3% | 5 | -1 | $694 | $40,997 | 5 | N/A | false | false |
| 11 | 8 | Marley & Me | $2,588 | -40.2% | 3 | -1 | $862 | $86,451 | 5 | N/A | false | false |
| 12 | 9 | The Wrestler | $1,866 | -33.9% | 3 | - | $622 | $16,803 | 3 | N/A | false | false |
| 13 | 11 | In Bruges | $1,592 | -29.6% | 2 | - | $796 | $26,238 | 5 | N/A | false | false |
| 14 | 10 | U2 3D | $1,555 | -41% | 1 | - | $1,555 | $33,128 | 5 | N/A | false | false |
| 15 | 12 | Bolt | $1,545 | -26.9% | 3 | - | $515 | $150,701 | 10 | N/A | false | false |
| 16 | 18 | Revolutionary Road | $1,153 | +9.6% | 2 | +1 | $576 | $40,530 | 6 | N/A | false | false |
| 17 | 17 | Doubt | $1,064 | -4% | 2 | - | $532 | $44,879 | 8 | N/A | false | false |
| 18 | 16 | Valkyrie | $927 | -36.6% | 1 | -2 | $927 | $83,545 | 7 | N/A | false | false |
| 19 | 15 | Changeling | $923 | -44.9% | 2 | - | $461 | $119,925 | 8 | N/A | false | false |
| 20 | 14 | The Tale of Despereaux | $919 | -47.9% | 3 | -3 | $306 | $14,830 | 3 | N/A | false | false |
| 21 | 13 | Yes Man | $608 | -70.3% | 2 | -1 | $304 | $139,346 | 8 | N/A | false | false |
| 22 | 21 | Che: Part One | $555 | +32.1% | 1 | - | $555 | $29,628 | 7 | N/A | false | false |
| 23 | 19 | Madagascar: Escape 2 Africa | $256 | -63% | 3 | - | $85 | $266,467 | 14 | Paramount Pictures International | false | false |
| 24 | 24 | Frost/Nixon | $253 | +1.2% | 1 | - | $253 | $7,729 | 4 | N/A | false | false |
| 25 | 22 | Tonky y Otros Amigos | $208 | -49.3% | 2 | -1 | $104 | $2,399 | 3 | N/A | false | false |
| 26 | 23 | My Brother is an Only Child | $198 | -37.1% | 1 | - | $198 | $16,932 | 14 | N/A | false | false |
| 27 | 26 | Frozen River | $154 | -20.6% | 1 | - | $154 | $2,512 | 5 | N/A | false | false |
