| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Bedtime Stories | $82,986 | -20.4% | 32 | -2 | $2,593 | $736,003 | 4 | Walt Disney Pictures | false | false |
| 2 | 2 | Slumdog Millionaire | $67,404 | -16.8% | 18 | -3 | $3,744 | $425,880 | 4 | Bazuca Films | false | false |
| 3 | - | Changeling | $62,915 | - | 32 | - | $1,966 | $62,915 | 1 | United International Pictures | true | false |
| 4 | 3 | Watchmen | $42,394 | -42% | 35 | -1 | $1,211 | $141,594 | 2 | United International Pictures | false | false |
| 5 | 4 | Valkyrie | $36,585 | -37.1% | 35 | -6 | $1,045 | $696,857 | 5 | 20th Century Fox International | false | false |
| 6 | 5 | Jonas Brothers: The 3D Concert Experience | $28,845 | -42% | 9 | +1 | $3,205 | $98,695 | 2 | Walt Disney Pictures | false | false |
| 7 | 7 | Impy's Island | $23,745 | -20.1% | 15 | -1 | $1,583 | $58,143 | 2 | Bazuca Films | false | false |
| 8 | 6 | The Curious Case of Benjamin Button | $18,849 | -47.7% | 23 | -4 | $819 | $1,022,604 | 8 | Warner Bros. | false | false |
| 9 | 8 | Righteous Kill | $15,754 | -43% | 17 | -1 | $926 | $51,423 | 2 | CDI Films | false | false |
| 10 | 10 | Friday the 13th | $15,747 | -20.9% | 15 | -2 | $1,049 | $222,505 | 5 | United International Pictures | false | false |
| 11 | 9 | Doubt | $15,477 | -31.2% | 7 | - | $2,211 | $78,750 | 3 | Walt Disney Pictures | false | false |
| 12 | 11 | He's Just Not That Into You | $13,808 | -25.3% | 8 | -3 | $1,726 | $196,833 | 5 | Warner Bros. | false | false |
| 13 | - | Death Defying Acts | $11,521 | - | 12 | - | $960 | $11,521 | 1 | Transeuropa | true | false |
| 14 | 15 | Hotel for Dogs | $7,834 | +10.6% | 10 | +1 | $783 | $233,514 | 8 | United International Pictures | false | false |
| 15 | 13 | Seven Pounds | $6,184 | -42% | 8 | -4 | $773 | $84,681 | 4 | Sony Pictures Releasing | false | false |
| 16 | 12 | The Bank Job | $5,438 | -49.3% | 3 | -9 | $1,812 | $54,382 | 3 | Transeuropa | false | false |
| 17 | 18 | The Strangers | $4,978 | -13.5% | 7 | - | $711 | $103,837 | 8 | Bazuca Films | false | false |
| 18 | 14 | The Duchess | $4,713 | -34.2% | 5 | +1 | $942 | $55,993 | 4 | United International Pictures | false | false |
| 19 | 16 | Coraline | $4,066 | -40.5% | 9 | -2 | $451 | $224,419 | 6 | United International Pictures | false | false |
| 20 | 23 | The Boy in the Striped Pajamas | $3,474 | +0.9% | 5 | +1 | $694 | $241,400 | 9 | Walt Disney Pictures | false | false |
| 21 | 20 | Bolt | $3,431 | -28.9% | 10 | -2 | $343 | $1,861,587 | 12 | Walt Disney Pictures | false | false |
| 22 | 17 | Inkheart | $2,722 | -57.4% | 6 | -7 | $453 | $346,993 | 6 | Warner Bros. | false | false |
| 23 | 24 | Che: Part One | $2,036 | -8.7% | 1 | - | $2,036 | $120,499 | 7 | Bazuca Films | false | false |
| 24 | 19 | Yes Man | $1,835 | -65.7% | 4 | -1 | $458 | $873,023 | 9 | Warner Bros. | false | false |
| 25 | 26 | Family Hero | $1,376 | -26.8% | 1 | - | $1,376 | $24,734 | 5 | Andes Films | false | false |
| 26 | 21 | Flawless | $846 | -78.2% | 3 | -5 | $282 | $22,229 | 3 | Bazuca Films | false | false |
| 27 | 22 | Twilight | $834 | -76.9% | 2 | -3 | $417 | $1,289,555 | 11 | Bazuca Films | false | false |
| 28 | 25 | The Tale of Despereaux | $613 | -70.9% | 3 | -6 | $204 | $154,734 | 7 | United International Pictures | false | false |
| 29 | - | The Spirit | $536 | - | 1 | - | $536 | $21,964 | 8 | Sony Pictures Releasing | false | false |
| 30 | 29 | Beverly Hills Chihuahua | $457 | -29% | 2 | -1 | $228 | $553,030 | 10 | Walt Disney Pictures | false | false |
| 31 | - | The Bottle | $180 | - | 1 | - | $180 | $5,615 | 3 | - | false | false |
