| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Marley & Me | $43,564 | - | 8 | - | $5,445 | $51,262 | 1 | Universal Pictures International (UPI) | true | false |
| 2 | 1 | Bolt | $27,222 | -37.5% | 9 | -1 | $3,024 | $236,267 | 3 | Universal Pictures International (UPI) | false | false |
| 3 | - | Watchmen | $21,151 | - | 6 | - | $3,525 | $21,151 | 1 | Universal Pictures International (UPI) | true | false |
| 4 | 2 | Slumdog Millionaire | $19,418 | -33.7% | 4 | - | $4,854 | $211,115 | 5 | ACME | false | false |
| 5 | 3 | The Unborn | $12,573 | -55.7% | 7 | - | $1,796 | $64,419 | 2 | Universal Pictures International (UPI) | false | false |
| 6 | - | The Crimson Wing: Mystery of the Flamingos | $6,403 | - | 4 | - | $1,600 | $6,710 | 1 | Universal Pictures International (UPI) | true | false |
| 7 | 6 | He's Just Not That Into You | $6,069 | -41.6% | 6 | - | $1,011 | $127,520 | 4 | - | false | false |
| 8 | 4 | The International | $5,565 | -58.5% | 7 | - | $795 | $28,761 | 2 | ACME | false | false |
| 9 | 5 | Inkheart | $4,344 | -60.6% | 6 | - | $724 | $26,095 | 2 | - | false | false |
| 10 | 11 | Fly Me to the Moon 3D | $2,330 | +9.9% | 1 | - | $2,330 | $120,994 | 8 | Universal Pictures International (UPI) | false | false |
| 11 | 9 | The Curious Case of Benjamin Button | $2,103 | -46.1% | 5 | - | $420 | $180,325 | 6 | Garsu Pasaulio Irasai | false | false |
| 12 | 8 | Seven Pounds | $2,089 | -50.6% | 4 | -1 | $522 | $35,855 | 3 | ACME | false | false |
| 13 | 7 | Role Models | $1,792 | -74.2% | 3 | - | $597 | $29,716 | 3 | Universal Pictures International (UPI) | false | false |
| 14 | 10 | Valkyrie | $1,340 | -63.9% | 4 | -1 | $335 | $70,565 | 4 | Universal Pictures International (UPI) | false | false |
| 15 | 12 | The Pink Panther 2 | $420 | -72.1% | 2 | -2 | $210 | $68,428 | 4 | ACME | false | false |
| 16 | 14 | U2 3D | $270 | -56.1% | 1 | - | $270 | $57,784 | 8 | Universal Pictures International (UPI) | false | false |
| 17 | 17 | Yes Man | $212 | -51.6% | 6 | +4 | $35 | $461,082 | 10 | Garsu Pasaulio Irasai | false | false |
| 18 | - | Bedtime Stories | $144 | - | 2 | - | $72 | $58,194 | 10 | Universal Pictures International (UPI) | false | false |
| 19 | 19 | Revolutionary Road | $120 | +7.1% | 1 | - | $120 | $49,708 | 7 | Universal Pictures International (UPI) | false | false |
| 20 | - | RocknRolla | $43 | - | 2 | - | $21 | $63,298 | 9 | Garsu Pasaulio Irasai | false | false |
