| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Slumdog Millionaire | $22,903 | -23.6% | 2 | - | $11,451 | $134,162 | 3 | ACME | false | false |
| 2 | - | Friday the 13th | $13,359 | - | 2 | - | $6,679 | $13,359 | 1 | Universal Pictures International (UPI) | true | false |
| 3 | 3 | Bolt | $12,513 | -11.5% | 8 | - | $1,564 | $163,651 | 5 | - | false | false |
| 4 | - | Race to Witch Mountain | $10,808 | - | 3 | - | $3,602 | $10,808 | 1 | - | true | false |
| 5 | 2 | Watchmen | $9,332 | -47.6% | 4 | +1 | $2,333 | $35,569 | 2 | Universal Pictures International (UPI) | false | false |
| 6 | 4 | He's Just Not That Into You | $9,016 | -10.4% | 3 | - | $3,005 | $107,559 | 5 | Universal Pictures International (UPI) | false | false |
| 7 | - | Seven Pounds | $7,208 | - | 1 | - | $7,208 | $7,208 | 1 | Universal Pictures International (UPI) | true | false |
| 8 | 5 | The Pink Panther 2 | $6,056 | -17% | 4 | - | $1,514 | $64,638 | 4 | Universal Pictures International (UPI) | false | false |
| 9 | 7 | The Curious Case of Benjamin Button | $5,149 | -15.6% | 4 | - | $1,287 | $150,175 | 7 | Universal Pictures International (UPI) | false | false |
| 10 | 6 | The International | $4,337 | -40.5% | 1 | -1 | $4,337 | $28,940 | 3 | Universal Pictures International (UPI) | false | false |
| 11 | 11 | Hotel for Dogs | $3,603 | -1.9% | 2 | - | $1,801 | $14,459 | 3 | Universal Pictures International (UPI) | false | false |
| 12 | 10 | Yes Man | $3,077 | -32.4% | 4 | - | $769 | $212,804 | 10 | Universal Pictures International (UPI) | false | false |
| 13 | 12 | My Bloody Valentine | $2,428 | +44.7% | 1 | - | $2,428 | $213,431 | 9 | ACME | false | false |
| 14 | 9 | The Heir Apparent: Largo Winch | $2,207 | -52.6% | 1 | - | $2,207 | $8,811 | 2 | ACME | false | false |
| 15 | 8 | First Love: It's the Music! | $1,918 | -59.8% | 2 | - | $959 | $8,811 | 2 | ACME | false | false |
| 16 | 15 | Madagascar: Escape 2 Africa | $1,242 | +19.5% | 9 | - | $138 | $345,264 | 14 | Universal Pictures International (UPI) | false | false |
| 17 | 14 | Doubt | $1,223 | -11.3% | 1 | - | $1,223 | $7,616 | 3 | Universal Pictures International (UPI) | false | false |
