| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Slumdog Millionaire | $20,165 | -15.1% | 6 | - | $3,360 | $198,759 | 5 | N/A | false | false |
| 2 | 2 | Stranded | $17,498 | -2.3% | 8 | +2 | $2,187 | $42,398 | 2 | N/A | false | false |
| 3 | 3 | Seven Pounds | $10,053 | -13.1% | 6 | - | $1,675 | $49,147 | 3 | N/A | false | false |
| 4 | 4 | Bride Wars | $9,347 | -16.7% | 5 | -1 | $1,869 | $45,205 | 2 | 20th Century Fox International | false | false |
| 5 | - | Coraline | $7,260 | - | 7 | - | $1,037 | $7,260 | 1 | N/A | true | false |
| 6 | - | Saw V | $7,165 | - | 5 | - | $1,433 | $7,165 | 1 | Walt Disney Pictures | true | false |
| 7 | - | Reasons for Not Falling in Love | $6,812 | - | 4 | - | $1,703 | $6,812 | 1 | N/A | true | false |
| 8 | 7 | Vicky Cristina Barcelona | $4,539 | -4.8% | 4 | +1 | $1,134 | $204,121 | 7 | N/A | false | false |
| 9 | 5 | The Pink Panther 2 | $4,411 | -36.8% | 5 | -5 | $882 | $88,970 | 5 | Sony Pictures Releasing | false | false |
| 10 | - | Death Defying Acts | $3,912 | - | 4 | - | $978 | $3,912 | 1 | N/A | true | false |
| 11 | 8 | Bedtime Stories | $2,930 | -26.6% | 4 | -1 | $732 | $119,927 | 7 | N/A | false | false |
| 12 | 6 | The Curious Case of Benjamin Button | $2,544 | -55.4% | 4 | -1 | $636 | $185,937 | 8 | N/A | false | false |
| 13 | 14 | U2 3D | $2,223 | +43% | 1 | - | $2,223 | $36,832 | 6 | N/A | false | false |
| 14 | 10 | Milk | $1,796 | -48.2% | 3 | -2 | $598 | $43,995 | 6 | N/A | false | false |
| 15 | 9 | Wild Child | $1,299 | -65.4% | 4 | -1 | $324 | $5,765 | 2 | N/A | false | false |
| 16 | 16 | Revolutionary Road | $1,293 | +12.1% | 2 | - | $646 | $42,243 | 7 | N/A | false | false |
| 17 | 17 | Doubt | $1,116 | +4.9% | 2 | - | $558 | $46,392 | 9 | N/A | false | false |
| 18 | 19 | Changeling | $1,056 | +14.4% | 1 | -1 | $1,056 | $163,468 | 9 | N/A | false | false |
| 19 | 11 | Marley & Me | $743 | -71.3% | 2 | -1 | $371 | $87,936 | 6 | N/A | false | false |
| 20 | 13 | In Bruges | $665 | -58.2% | 1 | -1 | $665 | $27,221 | 6 | N/A | false | false |
| 21 | 20 | The Tale of Despereaux | $559 | -39.2% | 3 | - | $186 | $15,572 | 4 | N/A | false | false |
| 22 | 18 | Valkyrie | $519 | -44% | 1 | - | $519 | $85,002 | 8 | N/A | false | false |
| 23 | 22 | Che: Part One | $423 | -23.8% | 1 | - | $423 | $31,047 | 8 | N/A | false | false |
| 24 | 23 | Madagascar: Escape 2 Africa | $346 | +35.2% | 3 | - | $115 | $266,814 | 15 | Paramount Pictures International | false | false |
| 25 | 24 | Frost/Nixon | $244 | -3.6% | 1 | - | $244 | $8,083 | 5 | N/A | false | false |
