| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Friday the 13th | $219,987 | - | 20 | - | $10,999 | $219,987 | 1 | United International Pictures | true | false |
| 2 | - | He's Just Not That Into You | $180,290 | - | 20 | - | $9,014 | $180,290 | 1 | Italian International Film | true | false |
| 3 | - | Mnahy | $97,506 | - | 20 | - | $4,875 | $97,506 | 1 | N/A | true | false |
| 4 | 1 | Race to Witch Mountain | $93,505 | -58.6% | 18 | -2 | $5,194 | $366,611 | 2 | N/A | false | false |
| 5 | 3 | Hotel for Dogs | $78,836 | -36% | 17 | -2 | $4,637 | $221,415 | 2 | United International Pictures | false | false |
| 6 | 4 | Nims Bond | $43,274 | -52.1% | 14 | - | $3,091 | $165,189 | 2 | N/A | false | false |
| 7 | 2 | Gran Torino | $41,534 | -71.5% | 9 | -10 | $4,614 | $225,430 | 2 | N/A | false | false |
| 8 | - | Trade | $35,902 | - | 8 | - | $4,487 | $35,902 | 1 | N/A | true | false |
| 9 | 8 | Slumdog Millionaire | $31,642 | -23.9% | 12 | +1 | $2,636 | $1,259,005 | 9 | Gulf Film | false | false |
| 10 | 6 | Marley & Me | $23,780 | -63.6% | 5 | -7 | $4,756 | $366,715 | 3 | N/A | false | false |
| 11 | - | Jonas Brothers: The 3D Concert Experience | $22,812 | - | 8 | - | $2,851 | $22,812 | 1 | N/A | true | false |
| 12 | 7 | Watchmen | $15,245 | -74% | 14 | -10 | $1,088 | $487,972 | 3 | United International Pictures | false | false |
| 13 | 5 | The Midnight Meat Train | $10,762 | -87.1% | 12 | -6 | $896 | $115,880 | 2 | N/A | false | false |
| 14 | 9 | The Pink Panther 2 | $10,352 | -57.6% | 2 | -3 | $5,176 | $829,372 | 6 | N/A | false | false |
| 15 | 12 | The Curious Case of Benjamin Button | $4,566 | -51.4% | 1 | -1 | $4,566 | $615,943 | 5 | N/A | false | false |
| 16 | 10 | What Just Happened | $4,329 | -79.2% | 2 | -12 | $2,164 | $134,022 | 3 | Gulf Film | false | false |
| 17 | 15 | Confessions of a Shopaholic | $3,506 | -38.7% | 1 | - | $3,506 | $361,219 | 5 | N/A | false | false |
| 18 | 18 | My Mom's New Boyfriend | $1,806 | -13.1% | 1 | - | $1,806 | $163,146 | 8 | N/A | false | false |
| 19 | 20 | Madagascar: Escape 2 Africa | $1,538 | -10.1% | 1 | - | $1,538 | $1,906,696 | 17 | N/A | false | false |
| 20 | 17 | Garfield's Fun Fest | $1,399 | -42.4% | 1 | - | $1,399 | $121,299 | 5 | N/A | false | false |
| 21 | 14 | Bella | $1,139 | -80.3% | 1 | -3 | $1,139 | $9,122 | 2 | N/A | false | false |
| 22 | 22 | Twilight | $1,109 | -21.3% | 1 | - | $1,109 | $1,254,666 | 16 | N/A | false | false |
| 23 | 21 | Role Models | $494 | -66.9% | 1 | - | $494 | $135,192 | 6 | N/A | false | false |
| 24 | 19 | The Unborn | $400 | -77.5% | 1 | - | $400 | $512,033 | 7 | N/A | false | false |
| 25 | 23 | Day of the Dead | $65 | -92.9% | 1 | -2 | $65 | $223,460 | 4 | N/A | false | false |
