| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Gran Torino | $1,555,238 | -28.9% | 263 | - | $5,913 | $8,145,094 | 3 | Warner Bros. | false | false |
| 2 | - | Marley & Me | $1,019,505 | - | 303 | - | $3,364 | $1,282,052 | 1 | 20th Century Fox International | true | false |
| 3 | - | Duplicity | $993,328 | - | 301 | - | $3,300 | $1,287,434 | 1 | United International Pictures | true | false |
| 4 | 3 | Bedtime Stories | $756,719 | -37% | 380 | -20 | $1,991 | $4,544,722 | 3 | Walt Disney Pictures | false | false |
| 5 | 2 | Underworld: Rise of the Lycans | $725,980 | -52.9% | 297 | - | $2,444 | $2,700,438 | 2 | Sony Pictures Releasing | false | false |
| 6 | 4 | Slumdog Millionaire | $683,031 | -28.1% | 252 | -1 | $2,710 | $10,561,235 | 6 | Filmax | false | false |
| 7 | 6 | Hotel for Dogs | $412,538 | -18.4% | 220 | - | $1,875 | $1,065,998 | 2 | Paramount Pictures International | false | false |
| 8 | 5 | Watchmen | $337,306 | -51.9% | 361 | -65 | $934 | $3,589,998 | 3 | Paramount Pictures International | false | false |
| 9 | 7 | The Code | $258,585 | -41.9% | 218 | -1 | $1,186 | $1,799,424 | 3 | DeAPlaneta | false | false |
| 10 | 8 | The Reader | $232,742 | -36.1% | 192 | -14 | $1,212 | $5,181,129 | 6 | On Pictures | false | false |
| 11 | 9 | The Curious Case of Benjamin Button | $199,816 | -42% | 216 | -92 | $925 | $15,071,816 | 7 | Warner Bros. | false | false |
| 12 | 10 | The Pink Panther 2 | $167,363 | -48.6% | 279 | -73 | $599 | $3,616,445 | 4 | Sony Pictures Releasing | false | false |
| 13 | 12 | Blindness | $162,702 | -42.1% | 119 | -1 | $1,367 | $544,904 | 2 | Notro Films | false | false |
| 14 | 11 | The Burning Plain | $157,961 | -49.8% | 101 | - | $1,563 | $588,706 | 2 | United International Pictures | false | false |
| 15 | 14 | The Visitor | $121,956 | -12.7% | 52 | - | $2,345 | $335,890 | 2 | Karma Films | false | false |
| 16 | 13 | Beverly Hills Chihuahua | $98,597 | -36.3% | 210 | -37 | $469 | $7,344,154 | 7 | Walt Disney Pictures | false | false |
| 17 | 15 | Doubt | $40,314 | -44.8% | 74 | -16 | $544 | $3,226,743 | 8 | Walt Disney Pictures | false | false |
| 18 | 16 | Push | $32,049 | -53.3% | 67 | -68 | $478 | $2,710,900 | 5 | - | false | false |
| 19 | - | Cloud 9 | $31,817 | - | 27 | - | $1,178 | $39,992 | 1 | Baditri | true | false |
| 20 | 21 | Cherry Blossoms | $26,460 | -34% | 30 | -5 | $882 | $177,354 | 3 | Wanda Visión S.A. | false | false |
| 21 | 22 | Welcome to the Sticks | $23,289 | -36.8% | 24 | -15 | $970 | $4,284,777 | 11 | Wanda Visión S.A. | false | false |
| 22 | 20 | In the Name of the King: A Dungeon Siege Tale | $22,676 | -51.2% | 64 | -51 | $354 | $1,150,471 | 4 | New World Pictures | false | false |
| 23 | 17 | Che: Part Two | $22,483 | -63.7% | 64 | -89 | $351 | $1,011,407 | 4 | 20th Century Fox International | false | false |
| 24 | 23 | Seven Pounds | $18,292 | -46.2% | 49 | -22 | $373 | $13,433,101 | 10 | Sony Pictures Releasing | false | false |
| 25 | 25 | The Class | $17,980 | -24% | 22 | -1 | $817 | $1,606,548 | 10 | Golem Distribución | false | false |
| 26 | 19 | Lost in Galicia | $17,926 | -63.3% | 46 | -2 | $389 | $86,078 | 2 | Walt Disney Pictures | false | false |
| 27 | 18 | The Baader Meinhof Complex | $17,789 | -64.9% | 61 | -28 | $291 | $90,214 | 2 | - | false | false |
| 28 | - | Captain Abu Raed | $15,522 | - | 19 | - | $816 | $21,493 | 1 | Golem Distribución | true | false |
| 29 | 24 | Revolutionary Road | $11,406 | -62.4% | 24 | -11 | $475 | $5,225,076 | 9 | Paramount Pictures International | false | false |
| 30 | 26 | Let it Rain | $10,865 | -49.7% | 15 | -7 | $724 | $200,081 | 4 | - | false | false |
| 31 | 32 | El libro de las aguas | $9,660 | +2.6% | 5 | - | $1,932 | $167,263 | 19 | Independent Films | false | false |
| 32 | 29 | The Wrestler | $9,236 | -29.8% | 26 | -2 | $355 | $1,009,805 | 5 | United International Pictures | false | false |
| 33 | 27 | Valkyrie | $5,894 | -64.1% | 22 | -16 | $267 | $7,556,176 | 8 | 20th Century Fox International | false | false |
| 34 | 28 | Friday the 13th | $5,771 | -58.6% | 24 | -13 | $240 | $1,808,429 | 6 | Paramount Pictures International | false | false |
| 35 | 30 | The Milk of Sorrow | $5,231 | -50.6% | 10 | -6 | $523 | $210,707 | 6 | Wanda Visión S.A. | false | false |
| 36 | 37 | The Missing Lynx | $4,615 | +2.4% | 18 | -4 | $256 | $1,441,501 | 13 | - | false | false |
| 37 | 31 | Waltz with Bashir | $4,084 | -60.7% | 9 | -4 | $453 | $183,820 | 5 | Golem Distribución | false | false |
| 38 | 35 | Milk | $3,350 | -54.2% | 7 | -4 | $478 | $1,688,084 | 11 | United International Pictures | false | false |
| 39 | 34 | El Zorro de San Adrian | $2,321 | -71.3% | 7 | -4 | $331 | $20,376 | 7 | Barton Films | false | false |
| 40 | - | The Wave | $2,080 | - | 5 | - | $416 | $1,683,147 | 17 | - | false | false |
| 41 | 40 | The Way | $1,833 | -33.9% | 3 | -1 | $611 | $2,148,884 | 23 | Alta Films | false | false |
| 42 | 38 | Bolt | $1,782 | -53.7% | 15 | -16 | $118 | $10,413,271 | 16 | Walt Disney Pictures | false | false |
| 43 | 44 | The Broken | $1,502 | +10.4% | 4 | +1 | $375 | $18,878 | 4 | Independent Films | false | false |
| 44 | 50 | The Tale of Despereaux | $1,436 | +58.5% | 6 | -4 | $239 | $3,746,050 | 14 | Universal Pictures International (UPI) | false | false |
| 45 | 39 | Frost/Nixon | $1,318 | -56.2% | 5 | - | $263 | $436,853 | 7 | Universal Pictures International (UPI) | false | false |
| 46 | 36 | In Search of a Midnight Kiss | $1,270 | -79.7% | 2 | -1 | $635 | $439,808 | 16 | Sherlock Films | false | false |
| 47 | 33 | The Hanged Man | $1,038 | -88.1% | 12 | +3 | $86 | $460,652 | 8 | Sony Pictures Releasing | false | false |
| 48 | 52 | El ratón Pérez 2 | $755 | -6.8% | 4 | -2 | $188 | $1,119,744 | 15 | Filmax | false | false |
| 49 | 51 | Ghost Town | $748 | -10.4% | 6 | -1 | $124 | $110,710 | 4 | Paramount Pictures International | false | false |
| 50 | 59 | The Last Deadly Mission | $689 | +167.1% | 4 | +2 | $172 | $5,434 | 4 | Versus Entertainment | false | false |
| 51 | 41 | The Equation of Love and Death | $658 | -73.7% | 2 | -1 | $329 | $4,232 | 2 | Barton Films | false | false |
| 52 | 48 | Madagascar: Escape 2 Africa | $616 | -46.3% | 6 | -6 | $102 | $19,605,368 | 17 | Paramount Pictures International | false | false |
| 53 | 43 | Julia | $599 | -62.4% | 6 | - | $99 | $71,181 | 4 | Vértigo Films | false | false |
| 54 | 46 | Vicky Cristina Barcelona | $454 | -63.7% | 5 | -1 | $90 | $9,862,445 | 27 | Warner Bros. | false | false |
| 55 | 57 | Easy Virtue | $400 | +37% | 2 | - | $200 | $1,868,900 | 12 | DeAPlaneta | false | false |
| 56 | 45 | Mediterranean Food | $317 | -76.1% | 3 | -5 | $105 | $819,738 | 7 | Alta Films | false | false |
| 57 | 58 | Rachel Getting Married | $291 | +10.2% | 1 | - | $291 | $284,952 | 21 | Sony Pictures Releasing | false | false |
| 58 | 42 | Role Models | $213 | -87% | 4 | -5 | $53 | $1,671,187 | 8 | Universal Pictures International (UPI) | false | false |
| 59 | 62 | The One-Handed Trick | $174 | -14.7% | 1 | -2 | $174 | $490,936 | 10 | Alta Films | false | false |
| 60 | 63 | Forever Waiting | $127 | -37.7% | 1 | -1 | $127 | $13,504 | 5 | Barton Films | false | false |
| 61 | 54 | Changeling | $126 | -71.6% | 1 | -1 | $126 | $10,714,946 | 14 | Universal Pictures International (UPI) | false | false |
| 62 | 66 | Cadillac Records | $117 | +33% | 1 | - | $117 | $39,313 | 5 | Sony Pictures Releasing | false | false |
| 63 | 60 | The Unborn | $94 | -62.2% | 1 | -1 | $94 | $3,325,684 | 10 | Universal Pictures International (UPI) | false | false |
