| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Underworld: Rise of the Lycans | $181,379 | - | 31 | - | $5,850 | $181,379 | 1 | Sony Pictures Releasing | true | false |
| 2 | - | Inkheart | $155,522 | - | 26 | - | $5,981 | $155,522 | 1 | N/A | true | false |
| 3 | - | Confessions of a Shopaholic | $144,836 | - | 35 | - | $4,138 | $144,836 | 1 | Walt Disney Pictures | true | false |
| 4 | 1 | Paul Blart: Mall Cop | $140,883 | -28% | 35 | - | $4,025 | $761,727 | 3 | Sony Pictures Releasing | false | false |
| 5 | 2 | Bedtime Stories | $118,901 | -26.7% | 48 | +1 | $2,477 | $3,295,122 | 7 | Walt Disney Pictures | false | false |
| 6 | 3 | Gran Torino | $86,320 | -25.7% | 31 | +1 | $2,784 | $279,373 | 2 | Warner Bros. | false | false |
| 7 | 4 | Slumdog Millionaire | $55,379 | -25% | 11 | +1 | $5,034 | $703,457 | 5 | N/A | false | false |
| 8 | - | Captivity | $54,442 | - | 17 | - | $3,202 | $59,669 | 1 | N/A | true | false |
| 9 | 5 | The International | $46,163 | -27.9% | 24 | -1 | $1,923 | $454,246 | 4 | Sony Pictures Releasing | false | false |
| 10 | 9 | Dan in Real Life | $31,398 | -33.8% | 18 | -7 | $1,744 | $361,503 | 4 | N/A | false | false |
| 11 | 6 | Funny Games | $30,779 | -44.1% | 15 | - | $2,051 | $132,489 | 2 | N/A | false | false |
| 12 | 8 | The Nanny Diaries | $26,274 | -44.8% | 15 | - | $1,751 | $103,887 | 2 | N/A | false | false |
| 13 | 11 | The Pink Panther 2 | $18,403 | -45.2% | 25 | -4 | $736 | $981,304 | 6 | Sony Pictures Releasing | false | false |
| 14 | 13 | The Duchess | $16,992 | -36.3% | 9 | -1 | $1,888 | $66,609 | 2 | United International Pictures | false | false |
| 15 | 12 | Yes Man | $16,583 | -45% | 16 | +2 | $1,036 | $3,340,820 | 10 | Warner Bros. | false | false |
| 16 | 21 | Hotel for Dogs | $14,833 | +16.8% | 20 | +2 | $741 | $1,211,264 | 10 | N/A | false | false |
| 17 | 16 | Deception | $14,762 | -37.7% | 11 | -4 | $1,342 | $140,527 | 3 | N/A | false | false |
| 18 | 10 | The Curious Case of Benjamin Button | $12,253 | -66.7% | 13 | -11 | $942 | $1,806,223 | 8 | N/A | false | false |
| 19 | 18 | Doubt | $12,138 | -21.9% | 11 | - | $1,103 | $288,211 | 5 | Walt Disney Pictures | false | false |
| 20 | 7 | Watchmen | $11,421 | -78.4% | 21 | -21 | $543 | $528,056 | 4 | N/A | false | false |
| 21 | 22 | Vicky Cristina Barcelona | $10,233 | -7.4% | 7 | +3 | $1,461 | $258,086 | 7 | N/A | false | false |
| 22 | 23 | Wild Child | $9,461 | -6.2% | 10 | -2 | $946 | $223,017 | 6 | N/A | false | false |
| 23 | 15 | Death Sentence | $9,070 | -62.7% | 8 | -8 | $1,133 | $328,279 | 5 | N/A | false | false |
| 24 | 17 | Friday the 13th | $8,620 | -50.1% | 5 | -8 | $1,724 | $836,973 | 7 | N/A | false | false |
| 25 | 24 | .45 | $6,723 | -23.1% | 7 | -3 | $960 | $117,133 | 5 | N/A | false | false |
| 26 | 14 | Valkyrie | $6,585 | -73.4% | 3 | -14 | $2,195 | $1,262,858 | 6 | N/A | false | false |
| 27 | 20 | Tear This Heart Out | $6,327 | -51.9% | 3 | -8 | $2,109 | $69,975 | 2 | 20th Century Fox International | false | false |
| 28 | 25 | Quarantine | $5,369 | -33.7% | 2 | -1 | $2,684 | $329,192 | 10 | N/A | false | false |
| 29 | 19 | Bride Wars | $4,424 | -67% | 4 | -2 | $1,106 | $1,028,611 | 8 | N/A | false | false |
| 30 | 28 | Mad Money | $4,417 | +36.6% | 2 | - | $2,208 | $245,024 | 9 | N/A | false | false |
| 31 | 27 | Over Her Dead Body | $2,713 | -33.5% | 5 | - | $542 | $296,529 | 7 | N/A | false | false |
| 32 | 26 | Rudo y Cursi | $1,109 | -73% | 7 | -5 | $158 | $49,224 | 3 | N/A | false | false |
| 33 | 31 | Seven Pounds | $405 | -72.8% | 2 | - | $202 | $1,324,899 | 11 | N/A | false | false |
